Expression of Ets-1, Ang-2 and maspin in ovarian cancer and their role in tumor angiogenesis

Journal of Experimental and Clinical Cancer Research

Volumn 30, Issue 1, 2011, Pages

  Lin, Zijing ^a   Liu, Yu ^a   Sun, Yuhui ^a   He, Xiuping ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN 2; MASPIN; TRANSCRIPTION FACTOR ETS 1; ETS1 PROTEIN, HUMAN; SERINE PROTEINASE INHIBITOR; SERPIN B5; SERPIN-B5;

ADULT; AGED; ARTICLE; CARCINOGENESIS; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENERAL PATHOLOGICAL PARAMETERS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; OVARY CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; CANCER STAGING; GENE EXPRESSION PROFILING; GENETICS; MIDDLE AGED; NEOPLASM; NEOVASCULARIZATION (PATHOLOGY); OVARY TUMOR; PATHOLOGY; PROGNOSIS; VASCULARIZATION;

ADULT; ANGIOPOIETIN-2; FEMALE; GENE EXPRESSION PROFILING; HUMANS; MIDDLE AGED; NEOPLASM STAGING; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; OVARIAN NEOPLASMS; PROGNOSIS; PROTO-ONCOGENE PROTEIN C-ETS-1; SERPINS;

EID: 79953079029     PISSN: None     EISSN: 17569966     Source Type: Journal    
DOI: 10.1186/1756-9966-30-31     Document Type: Article

References (23)

1. Expression of angiogenesis-related genes in ovarian carcinoma-A clinicopathologic study. B Davidson I Goldberg J Kopolovic WH Gotlieb V Givant-Horwitz JM Nesland A Berner G Ben-Baruch M Bryne R Reich, Clin Exp Metastasis 2000 18 501 507 10.1023/A:1011858225144 11592307 (Pubitemid 32844251)
2. Vasculogenesis and angiogenesis as mechanisms of vascular network formation, growth and remodeling. S Patan, J Neurooncol 2000 50 1 15 10.1023/A:1006493130855 11245270 (Pubitemid 32166287)
3. Angiogenesis in epithelian ovarian cancer. ES Bamberger CW Perrett, Clin Pathol: Mol Pathol 2002 55 348 359 10.1136/mp.55.6.348 (Pubitemid 35454510)
4. Angiogenesis and ovarian cancer. C Gámez-Raposo M Mendiola J Barriuso E Casado D Hardisson A Redondo, Clin Transl Oncol 2009 11 564 571 19775995
5. Tumor-derived vascular endothelial growth factor up-regulates angiopoietin-2 in host endothelium and destabilizes host vasculature, supporting angiogenesis in ovarian cancer. L Zhang N Yang JW Park D Katsaros S Fracchioli G Cao A O'Brien-Jenkins TC Randall SC Rubin G Coukos, Cancer Res 2003 63 3403 3412 12810677 (Pubitemid 36735901)
6. Role of ETS family transcription factors in vascular development and angiogenesis. Y Sato, Cell Struct Funct 2001 26 19 24 10.1247/csf.26.19 11345500 (Pubitemid 32421948)
7. The Ets family contains transcriptional activators and repressors involved in angiogenesis. E Lelièvre F Lionneton F Soncin B Vandenbunder, Int J Biochem Cell Biol 2001 33 391 407 11312108 (Pubitemid 32324006)
8. c-ets proto-oncogene is a transcription factor expressed in endothelial cells during tumor vascularization and other forms of angiogenesis in humans. N Wernert MB Rase P Lassalle MP Dehouck B Gosselin B Vandenbunder D Stehelin, Am J Pathol 1992 140 119 127 1370594
9. Clinical implications of expression of ETS-1 in relation to angiogenesis in ovarian cancers. S Khatun J Fujimoto H Toyoki T Tamaya, Cancer Sci 2003 94 769 773 10.1111/j.1349-7006.2003.tb01517.x 12967474 (Pubitemid 37258774)
10. Angiopoietin 2 is a partial agonist/antagonist of tie2 signaling in the endothelium. HT Yuan EV Khankin SA Karumanchi SM Parikh, Mol cell Biol 2009 29 2011 2022 10.1128/MCB.01472-08 19223473
11. The temporal-spatial expression of VEGF, angiopoietin-1 and 2, and Tie-2 during tumor angiogenesis and their functional correlation with tumor neovascular architecture. V Tse L Xu YC Yung JG Santarelli D Juan K Fabel G Silverberg G Harsh, Neurol Res 2003 25 729 738 10.1179/016164103101202084 14579791 (Pubitemid 37266696)
12. Expression of maspin in non-muscle invasive bladder carcinoma; correlation with tumor angiogenesis and prognosis. MG Friedrich MI Toma S Petri JC Cheng P Hammerer A Erbersdobler H Huland, Eur Urol 2004 45 737 743 10.1016/j.eururo.2003.12.005 15149745 (Pubitemid 38638393)
13. Maspin overexpression correlates with increased expression of vascular endothelial growth factors A, C, and D in human ovarian carcinoma. F Bolat D Gumurdulu S Erkanli F Kayaselcuk H Zeren M Ali Vardar E Kuscu, Pathol Res Pract 2008 204 379 387 10.1016/j.prp.2008.01.011 18343598
14. Maspin expression in epithelial ovarian cancer and associations with poor prognosis: a gynecologic oncology group study. Gynecologic oncology group AA Secord PS Lee KM Darcy LJ Havrilesky LA Grace JR Marks A Berchuck, Gynecol Oncol 2006 101 390 397 10.1016/j.ygyno.2006.02.014 16551475 (Pubitemid 43744562)
15. Anatomic site-related expression of cancer-associated molecules in ovarian carcinoma. B Davidson, Curr cancer drug targets 2007 7 109 120 10.2174/156800907780006904 17305482 (Pubitemid 46345512)
16. Estrogen receptor analyses. Correlation of biochemical and immunohistochemical methods using monoclonal antireceptor antibodies. KS McCarty Jr LS Miller EB Cox J Konrath KS McCarty Sr, Arch Pathol Lab Med 1985 109 716 721 3893381 (Pubitemid 16237466)
17. Expression of angiopoietin-1, angiopoietin-2, and Tie2 genes in normal ovary with corpus luteum and in ovarian cancer. K Hata J Udagawa R Fujiwaki K Nakayama H Otani K Miyazaki, Oncology 2002 62 340 348 10.1159/000065066 12138242 (Pubitemid 34914103)
18. In Vivo evidence of angiogenesis induced by transcription factor Ets-1: Ets-1 is located upstream of angiogenesis cascade. N Hashiya N Jo M Aoki K Matsumoto T Nakmura Y Sato N Ogata T Ogihara Y Kaneda R Morishita, Circulation 2004 109 3035 3041 10.1161/01.CIR.0000130643.41587.DB 15173033 (Pubitemid 38811459)
19. c-Ets-1 is a promising marker in epithelial ovarian cancer. N Takai T Miyazaki M Nishida K Nasu I Miyakawa, Int J Mol Med 2002 9 287 292 11836635
20. The human myoepithelial cell is a natural tumor suppressor. MD Sternlicht P Kedeshian ZM Shao S Safarians SH Barsky, Clin Cancer Res 1997 3 1949 1958 9815584 (Pubitemid 27505120)
21. De-mystifying the mechanism of maspin. MJ Hendrix, Nat Med 2000 6 374 376 10.1038/74624 10742136
22. Transactivation through Ets and Ap1 Transcription sites determines the expression of the tumor-suppressing gene maspin. M Zhang N Maass D Magit R Sager, Cell growth differ 1997 8 179 186 9040939 (Pubitemid 27068895)
23. The paradoxical expression of maspin in ovarian carcinoma. AK Sood MS Fletcher LM Gruman JE Coffin S Jabbari Z Khalkhali-Ellis N Arbour EA Seftor MJ Hendrix, Clin Cancer Res 2002 8 2924 2932 12231537 (Pubitemid 35025740)