Regulation of CD1, Ki-67, PCNA mRNA expression, and Akt activation in estrogen-responsive human breast adenocarcinoma cell line, MCF-7 cells, by griffonianone C, an isoflavone derived from Millettia griffoniana

Pharmaceutical Biology

Volumn 49, Issue 4, 2011, Pages 341-347

  Magloire Ketcha Wanda, Germain Jean ^a,b   Njamen, Dieudonné ^a   Tagatsing, Fotsing Maurice ^a   Yankep, Emmanuel ^a   Vollmer, Günter ^b  

^a UNIVERSITY OF YAOUNDÉ I   (Cameroon)

^b DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Akt; gene expression regulation; Phytoestrogens; real time PCR; western blot analysis

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ANTINEOPLASTIC AGENT; CHLOROFORM; CYCLIN D1; CYCLINE; ESTROGEN; FULVESTRANT; GRIFFONIANONE C; ISOFLAVONE DERIVATIVE; KI 67 ANTIGEN; MESSENGER RNA; MILLETTIA GRIFFONIANA EXTRACT; PHOSPHATIDYLINOSITOL 3 KINASE; PLANT EXTRACT; PROTEIN KINASE B; SERINE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BREAST ADENOCARCINOMA; CANCER CELL CULTURE; CARCINOMA CELL; CELL PROLIFERATION; CELL STRAIN MCF 7; CELL SURVIVAL; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ESTROGEN RESPONSIVE ELEMENT; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MILLETTIA; MILLETTIA GRIFFONIANA; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

ADENOCARCINOMA; ANTIGENS, CD1; BREAST; BREAST NEOPLASMS; CELL LINE, TUMOR; CHROMONES; ENZYME INHIBITORS; FEMALE; GENE EXPRESSION PROFILING; GRIFFONIA; HUMANS; KI-67 ANTIGEN; MILLETTIA; MORPHOLINES; ONCOGENE PROTEIN V-AKT; PHYTOTHERAPY; PLANT PREPARATIONS; PLANT ROOTS; PROLIFERATING CELL NUCLEAR ANTIGEN; RNA, MESSENGER; TUMOR CELLS, CULTURED;

FABACEAE; MILLETTIA GRIFFONIANA;

EID: 79953077144     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880209.2010.517210     Document Type: Article

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