Microsphere-integrated drug-eluting stents: PLGA microsphere integration in hydrogel coating for local and prolonged delivery of hydrophilic antirestenosis agents

Journal of Biomedical Materials Research - Part A

Volumn 97 A, Issue 2, 2011, Pages 201-211

  Indolfi, Laura ^a   Causa, Filippo ^a   Giovino, Concetta ^a   Ungaro, Francesca ^a   Quaglia, Fabiana ^a   Netti, Paolo Antonio ^a,b  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

Author keywords

controlled drug release; hydrogel; microsphere; stent

Indexed keywords

BIPHASIC; COATING LAYER; CONTROLLED DRUG RELEASE; DRUG-ELUTING STENTS; FLEXIBLE PLATFORMS; FULLY INTEGRATED; HYDROGEL SURFACES; HYDROPHILIC MODEL; MICRO-PARTICLES; PLGA MICROSPHERES; POLY(D ,L-LACTIDE-CO- GLYCOLIDE); PROOF OF PRINCIPLES; RELEASE KINETICS; RELEASE PROFILES; RELEASE RATE; RESTENOSIS; STENT; SUSTAINED RELEASE;

ARTIFICIAL ORGANS; COATINGS; CONTROLLED DRUG DELIVERY; DEXTRAN; DRUG PRODUCTS; GLUCOSE; HYDROGELS; HYDROPHILICITY; INTEGRATION; ORGANIC POLYMERS;

MICROSPHERES;

DEXTRAN; MICROSPHERE; POLY(2 HYDROXY ETHYL METHACRYLATE); POLY(DEXTRO,LEVO LACTIDE CO GLYCOLIDE); UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG ELUTING STENT; DRUG RELEASE; HYDROGEL; HYDROPHILICITY; IN-STENT RESTENOSIS; MICROENCAPSULATION; MICROPARTICLE ENZYME IMMUNOASSAY;

ANIMALS; CHEMISTRY, PHARMACEUTICAL; CORONARY RESTENOSIS; DEXTRANS; DRUG DELIVERY SYSTEMS; DRUG-ELUTING STENTS; HUMANS; HYDROGELS; KINETICS; LACTIC ACID; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; POLYGLYCOLIC ACID; POLYMERS; SOLVENTS;

EID: 79953062808     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.33039     Document Type: Article

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