Tumor necrosis factor-α antibody eluting stents reduce vascular smooth muscle cell proliferation in saphenous vein organ culture

Experimental and Molecular Pathology

Volumn 73, Issue 2, 2002, Pages 104-111

  Javed, Qamar ^a   Swanson, Neil ^a   Vohra, Hunaid ^a   Thurston, Herbert ^b   Gershlick, Anthony H ^a  

^a GLENFIELD HOSPITAL   (United Kingdom)

^b Robert Kilpatrick Clinical Sciences Building ^*  (United Kingdom)

Author keywords

Drug eluting stents; Restenosis; TNF expression; Venous organ culture

Indexed keywords

CYCLINE; CYTOKINE; TRANSFORMING GROWTH FACTOR ALPHA;

ADSORPTION; ARTICLE; CELL LYSATE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; ELUTION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MOLECULAR BIOLOGY; ORGAN CULTURE; SAPHENOUS VEIN; SMOOTH MUSCLE FIBER; STENT; VASCULAR SMOOTH MUSCLE;

EID: 0036382590     PISSN: 00144800     EISSN: None     Source Type: Journal    
DOI: 10.1006/exmp.2002.2450     Document Type: Article

References (28)

1. Aggarwal, R. K., Ireland, D. C., Azrin, M. A., Ezekowitz, M. D., de Bono, D. P., and Gershlick, A. H. (1996). Antithrombotic potential of polymer-coated stents eluting platelet glycoprotein IIb/IIIa receptor antibody. Circulation 94(12), 3311-3317.
2. Barath, P., Fisfbien, M. C., Cao, J., Berenson, J., Helfant, R. H., and Forrester, J. S. (1990). Detection and localisation of tumour necrosis factor in human atheroma. Am. J. Cardiol. 65, 297-302.
3. Barath, P., Fishbien, M. C., Cao, J., Berenson, J., Helfant, R. H., and Forrester, J. S. (1990). Tumour necrosis factor gene expression in human vascular intimal smooth muscle cells detected by in situ hybridisation. Am. J. Pathol. 137, 503-509.
4. Baron, J. H., Gershlick, A. H., Hogrefe, K., Armstrong, J., Holt, C. M., Aggarwal, R. K., Azrin, M., Ezekowitz, M., and de Bono, D. P. (2000). In vitro evaluation of c7E3-Fab (ReoPro) eluting polymer-coated coronary stents. Cardiovasc. Res. 46(3), 585-594.
5. Bradford, M. M. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
6. Clausell, N., de Lima, V. C., Molossi, S., Liu, P., Turley, E., Gotleib, A. I., Adelman, A. G., and Rabinovitch, M. (1995). Expression of tumour necrosis factor-α and accumulation of fibronectin in coronary artery restenotic lesions retrieved by atherectomy. Br. Heart. J. 73, 534-539.
7. Clausell, N., Molossi, S., Sett, S., and Rabinovitch, M. (1994). In vivo blockade of tumor necrosis factor-alpha in cholesterol-fed rabbits after cardiac transplant inhibits acute coronary artery neointimal formation. Circulation 89(6), 2468-2779.
8. Farb, A., Sangiorgi, G., Carter, A. J., Walley, V. M., Edwards, W. D., Schwartz, R. S., and Virmani, R. (1999). Pathology of acute and chronic coronary stenting in humans. Circulation 99, 44-52.
9. Ferns, G. A., Raines, E. W., Sprugel, K. H., Motani, A. S., Reidy, M. A., and Ross, R. (1991). Inhibition of intimal smooth muscle accumulation after angioplasty by an antibody to PDGF. Science 253, 1129-1132.
10. Foo, R. S. Y., Gershlick, A. H., Hogrefe, K., Baron, J. H., Johnston, T. W., Hussey, A. J., Garner, I., and de Bono, D. P. (1999). Inhibition of platelet thrombosis using an Activated Protein C-loaded stent: In vitro and in vivo results. Thromb. Haemostasis 83, 496-502.
11. Goetze, S., Xi, X. P., Kawano, Y., Kawano, H., Fleck, E., Hsueh, W. A., and Law, R. E. (1999). TNF-alpha-induced migration of vascular smooth muscle cells is MAPK dependent. Hypertension 33(1 Pt. 2), 183-189.
12. Heldman, A. W., Cheng, L., Jenkins, G. M., Heller, P. F., Kim, D. W., Ware, M., Jr., Nater, C., Hruban, R. H., Rezai, B., Abella, B. S., Bunge, K. E., Kinsella, J. L., Sollott, S. J., Lakatta, E. G., Brinker, J. A., Hunter, W. L., and Froehlich, J. P. (2001). Paclitaxel stent coating inhibits neointimal hyperolasia at 4 weeks in a porcine model of coronary restenosis. Circulation 103, 2289-2295.
13. Javed, Q., Swanson, N., Warner, E. L., Gershlick, A. H., and de Bono, D. P. (2001). Plasminogen activator and plasminogen activator inhibitor gene expression in human saphenous vein organ culture. Exp. Mol. Pathol. 70, 146-153.
14. Jovinge, S., Hultgardh-Nilsson, A., Regnstrom, J., and Nilsson, J. (1997). Tumour necrosis factor-alpha activates smooth muscle cell migration in culture and is expressed in the balloon-injured rat aorta. Arterioscler. Thromb. Vasc. Biol. 17(3), 490-497.
15. Kearney, M., Pieczek, A., Haley, L., Losordo, D. W., Andres, V., Schain-feld, R., Rosenfield, K., and Isner, J. M. (1997). Histopathology of in-stent restenosis in patients with peripheral artery disease. Circulation 95, 1998-2002.
16. Klugherz, B. D., DeAngelo, D. L., Kim, B. K., Herrmann, H. C., Hirshfeld, J. W., and Kolansky, D. M. (1996). Three-year clinical follow-up after Palmaz-Schatz stenting. JACC 27, 1185-1191.
17. Komatsu, R., Ueda, M., Naruko, T., Kojima, A., and Becker, A. E. (1998). Neointimal tissue response at sites of coronary stenting in humans: Macroscopic, histological, and immunohistochemical analyses. Circulation 98, 224-233.
18. Kranzhofer, A., Baker, A. H., George, S. J., and Newby, A. C. (1999). Expression of tissue inhibitor of metalloproteinases-1, -2, and -3 during neointimal formation in organ cultures of human saphenous vein. Arterioscler. Thromb. Vasc. Biol. 17(3), 490-497.
19. Majesky, M. W., Linder, V., Twardzik, D. R., Schwartz, S. M., and Reidy, M. A. (1991). Production of transforming growth factor beta 1 during repair of arterial injury. J. Clin. Invest. 88, 904-910.
20. Moiseeva, E. P., Javed, Q., Spring, E. L., and de Bono, D. P. (2000). Galectin 1 is involved in vascular smooth muscle cell proliferation. Cardiovasc. Res. 45, 493-502.
21. Porter, K. E., Varty, K., Jones, L., Bell, P. R., and London, N. J. (1996). Human saphenous vein organ culture: A useful model of intimal hyperplasia? Eur. J. Vasc. Endovasc. Surg. 11, 48-58.
22. Rus, H. G., Niculescu, F., and Vlaicu, R. (1991). Tumour necrosis factor-alpha in human arterial wall with atherosclerosis. Atherosclerosis 89, 247-254.
23. Spyridopoulos, I., Principe, N., Krasinski, K. L., Xu, S. H., Kearney, M., Magner, M., Isner, J. M., and Losordo, D. W. (1998). Restoration of E2F expression rescues vascular endothelial cells from tumor necrosis factor-alpha-induced apoptosis. Circulation 98, 2883-2890.
24. Swanson, N. M., Baron, J. H., Hogrefe, K., Javed, Q., and Gershlick, A. H. (2000). Novel delivery of vascular endothelial growth factor using polymer-coated stents: Loading and elution characteristics. Heart 83, P28.
25. Swanson, N., Hogrefe, K., Javed, Q., Azrin, M. A., and Gershlick, A. H. (2001). VEGF-eluting stents stimulate endothelial cell growth in vitro. JACC. 37(Suppl.), P1A(1038-12).
26. Tanaka, H., Sukhova, G., Schwartz, D., and Libby, P. (1996). Original contributions proliferating arterial smooth muscle cells after balloon injury express TNF-alpha but not interleukin-1 or basic fibroblast growth factor. Arterioscler. Thromb. Vasc. Biol. 16, 12-18.
27. Voisard, R., Osswald, M., Baur, R., Jakob, U., Susa, M., Mattfeldt, T., Hemmer, W., Hannekum, A., Koenig, W., and Hombach, V. (1998). Expression of intercellular adhesion molecule-1 in human coronary endothelial and smooth muscle cells after stimulation with tumor necrosis factor-alpha. Coronary artery disease 9(11), 737-745.
28. Wilson, Y. G., Davies, A. H., Southgate, K., Currie, I. C., Knight, D., Patton, D., and Baird, R. N., Lamont, P. M., and Angelini, G. D. (1996). Influence of angioscopic vein graft preparation on developmental of neointimal hyperplasia in an organ culture model of human saphenous vein. J. Endovasc. Surg. 3, 436-444.