Approaches to immunotherapies for Japanese cedar pollinosis

Auris Nasus Larynx

Volumn 38, Issue 4, 2011, Pages 431-438

  Sakaguchi, Masahiro ^a   Hirahara, Kazuki ^b   Fujimura, Takashi ^c   Toda, Masako ^d  

^a AZABU UNIVERSITY   (Japan)

^b DAIICHI SANKYO CO   (Japan)

^c Institute of Physical and Chemical Research   (Japan)

^d PAUL EHRLICH INSTITUT   (Germany)

Author keywords

Allergen; CpG; Immunotherapy; Peptide; Pollen; Vaccine

Indexed keywords

ANTIALLERGIC AGENT; CPG OLIGODEOXYNUCLEOTIDE; CRYPTOMERIA JAPONICA EXTRACT; DNA VACCINE; EPITOPE; IMMUNOLOGICAL ADJUVANT; JAPANESE CEDAR ALLERGEN; PEPTIDE VACCINE; PLACEBO; PLANT ANTIGEN; PLANT EXTRACT; PLASMID DNA; POLLEN ANTIGEN; PULLULAN; UNCLASSIFIED DRUG;

CELL BASED GENE THERAPY; CYTOKINE PRODUCTION; DOSE RESPONSE; DRUG DOSE INCREASE; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG SAFETY; EXPRESSION VECTOR; GENE INACTIVATION; HUMAN; IMMUNE RESPONSE; IMMUNOTHERAPY; INOCULATION; INSECT ALLERGY; JAPANESE CEDAR; NONHUMAN; POLLEN ALLERGY; REVIEW; RICE; T LYMPHOCYTE; TRANSGENIC PLANT; UNSPECIFIED SIDE EFFECT; VACCINE PRODUCTION;

ADMINISTRATION, ORAL; ADMINISTRATION, SUBLINGUAL; ALLERGENS; ANIMALS; CRYPTOMERIA; EPITOPES, T-LYMPHOCYTE; HUMANS; IMMUNOTHERAPY; MICE; MICE, TRANSGENIC; RHINITIS, ALLERGIC, SEASONAL; VACCINES, CONJUGATE; VACCINES, DNA;

EID: 79953047279     PISSN: 03858146     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.anl.2010.12.002     Document Type: Review

References (36)

1. Noon L. Prophylactic inoculation against hay fever. Lancet 1911, i:1572-1573.
2. Nelson H.S. Immunotherapy for the inhalant allergens. Allergy 2009, Elsevier, Philadelphia, PA, pp1455-1473.
3. Yasueda H., Yui Y., Shimizu T., Shida T. Isolation and partial characterization of the major allergen from Japanese cedar (Cryptomeria japonica) pollen. J Allergy Clin Immunol 1983, 71:77-86.
4. Sakaguchi M., Inouye S., Taniai M., Ando S., Usui M., Matuhasi T. Identification of the second major allergen of Japanese cedar pollen. Allergy 1990, 45:309-312.
5. Fujimura T., Futamura N., Midoro-Horiuti T., Togawa A., Goldblum R.M., Yasueda H., et al. Isolation and characterization of native Cry j 3 from Japanese cedar (Cryptomeria japonica) pollen. Allergy 2007, 62:547-553.
6. Horiguchi S., Okamoto Y., Yonekura S., Okawa T., Yamamoto H., Kunii N., et al. A randomized controlled trial of sublingual immunotherapy for Japanese cedar pollinosis. Int Arch Allergy Immunol 2008, 146:76-84.
7. Takagi H., Hiroi T., Yang L., Tada Y., Yuki Y., Takamura K., et al. A rice-based edible vaccine expressing multiple T cell epitopes induces oral tolerance for inhibition of Th2-mediated IgE responses. Proc Natl Acad Sci USA 2005, 102:17525-17530.
8. Hirahara K., Saito S., Serizawa N., Sasaki R., Sakaguchi M., Inouye S., et al. Oral administration of a dominant T-cell determinant peptide inhibits allergen-specific TH1 and TH2 cell responses in Cry j 2-primed mice. J Allergy Clin Immunol 1998, 102:961-967.
9. Hirahara K., Tatuta T., Takatori T., Ohtsuki M., Kirinaka H., Kawaguchi J., et al. Preclinical evaluation of an immunotherapeutic peptide comprising 7 T-cell determinants of Cry j 1 and Cry j 2, the major Japanese cedar pollen allergens. J Allergy Clin Immunol 2001, 108:94-100.
10. Toda M., Sato H., Takebe Y., Taniguchi Y., Saito S., Inouye S., et al. Inhibition of immunoglobulin E response to Japanese cedar pollen allergen (Cry j 1) in mice by DNA immunization: different outcomes dependent on the plasmid DNA inoculation method. Immunology 2000, 99:179-186.
11. + T cell epitope peptide derived from Japanese cedar pollen allergen inhibits allergen-specific IgE response. Eur J Immunol 2002, 32:1631-1639.
12. Kaburaki Y, Fujimura, T, Kurata, K, Matsuda, K, Toda, M, Yasueda H, Chida K, Kawarai S, Sakaguchi M. Induction of Th1 immune response to Japanese cedar pollen allergen (Cry j 1) in mice immunized with CpG oligodeoxynucleotide-conjugated Cry j 1. Comp Immunol Micob Infect Dis; in press.
13. Okuda M., Shida T., Konno A., Fujita Y., Nakano K., Sakakura Y., et al. Comparative study of Japanese cedar pollen allergen-pullulan conjugate in immunotherapy with pollen extract. Otalogia Fukuoka 2002, 48:99-116. (in Japanese).
14. Okubo K., Gotoh M., Fujieda S., Okano M., Yoshida H., Morikawa H., et al. A randomized double-blind comparative study of sublingual immunotherapy for cedar pollinosis. Allergol Int 2008, 57:265-275.
15. + leukocytes, is a potential therapeutic biomarker for sublingual immunotherapy: a preliminary report. Int Arch Allergy Immunol 2010, 153:378-387.
16. Yamanaka K., Yuta A., Kakeda M., Sasaki R., Kitagawa H., Gabazza E.C., et al. Induction of IL-10-producing regulatory T cells with TCR diversity by epitope-specific immunotherapy in pollinosis. J Allergy Clin Immunol 2009, 124:842-845.
17. Müller U.R. Peptide immunotherapy. Allergy 1999, 54:45-46.
18. Norman P.S., Ohman J.L., Long A.A., Creticos P.S., Gefter M.A., Shaked Z., et al. Treatment of cat allergy with T-cell epitopes. Am J Respir Crit Care Med 1996, 154:1623-1628.
19. Oldfield W.L., Larché M., Kay A.B. Effect of T-cell peptides derived from Fel d 1 on allergic reactions and cytokine production in patients sensitive to cats: a randomized controlled trial. Lancet 2002, 360:47-53.
20. Müller U., Akdis C.A., Fricker M., Akdis M., Blesken T., Bettens F., et al. Successful immunotherapy with T-cell epitope peptides of bee venom phospholipase A2 induces specific T-cell anergy in patients allergic to bee venom. J Allergy Clin Immunol 1998, 101:747-754.
21. Sone T., Komiyama N., Shimizu K., Kusakabe T., Morikubo K., Kino K. Cloning and sequencing of cDNA coding for Cry j I, a major allergen of Japanese cedar pollen. Biochem Biophys Res Commun 1994, 199:619-625.
22. Namba M., Kurose M., Torigoe K., Hino K., Taniguchi Y., Fukuda S., et al. Molecular cloning of the second major allergen, Cry j II, from Japanese cedar pollen. FEBS Lett 1994, 353:124-128.
23. Saito S., Hirahara K., Kawaguchi J., Serizawa N., Hino K., Taniguchi Y., et al. Identification of T cell Determinants in Cry j 1 and Cry j 2 of size suitable for peptide immunotherapy against Japanese cedar pollinosis. An Rep Sankyo Res Lab 2000, 52:49-58.
24. Spiegeberg H.L., Raz E. DNA vaccines. Allergy 1999, 54:47-48.
25. Hsu C.H., Chua K.Y., Tao M.H., Lai Y.L., Wu H.D., Huang S.K., et al. Immunoprophylaxis of allergen-induced immunoglobulin E synthesis and airway hyperresponsiveness in vivo by genetic immunization. Nat Med 1996, 2:540-544.
26. Roy K., Mao H.Q., Huang S.K., Leong K.W. Oral gene delivery with chitosan - DNA nanoparticles generates immunologic protection in a murine model of peanut allergy. Nat Med 1999, 5:387-391.
27. Yamamoto S., Yamamoto T., Kataoka T., Kuramoto E., Yano O., Tokunaga T. Unique palindromic sequences in synthetic oligonucleotides are required to induce IFN and augment IFN-mediated natural killer activity. J Immunol 1992, 148:4072-4076.
28. Roman M., Martin-Orozco E., Goodman J.S., Nguyen M.D., Sato Y., Ronaghy A., et al. Immunostimulatory DNA sequences function as T helper-1-promoting adjuvants. Nat Med 1997, 3:849-854.
29. Busch R., Doebele R.C., Patil N.S., Pashine A., Mellins E.D. Accessory molecules for MHC class II peptide loading. Curr Opin Immunol 2000, 12:99-106.
30. Bakke O., Nordeng T.W. Intracellular traffic to compartments for MHC class II peptide loading: signals for endosomal and polarized sorting. Immunol Rev 1999, 172:171-187.
31. Tighe H., Takabayashi K., Schwartz D., Van Nest G., Tuck S., Eiden J.J., et al. Conjugation of immunostimulatory DNA to the short ragweed allergen Amb a 1 enhances its immunogenicity and reduces its allergenicity. J Allergy Clin Immunol 2000, 106:124-134.
32. Creticos P.S., Schroeder J.T., Hamilton R.G., Balcer-Whaley S.L., Khattignavong A.P., Lindblad R., et al. Immunotherapy with a ragweed-toll-like receptor 9 agonist vaccine for allergic rhinitis. N Engl J Med 2006, 355:1445-1455.
33. Horner A.A., Takabayashi K., Beck L., Sharma B., Zubeldia J., Baird S., et al. Optimized conjugation ratios lead to allergen immunostimulatory oligodeoxynucleotide conjugates with retained immunogenicity and minimal anaphylactogenicity. J Allergy Clin Immunol 2002, 110:413-420.
34. Suzuki M., Ohta N., Min W.P., Matsumoto T., Min R., Zhang X., et al. Immunotherapy with CpG DNA conjugated with T-cell epitope peptide of an allergenic Cry j 2 protein is useful for control of allergic condition in mice. Int Immunopharmacol 2007, 7:46-54.
35. Kawahara M., Mizutani K., Suzuki S., Kitamura S., Fukada H., Yui T., et al. Dependence of the mechanical properties of a pullulan film on the preparation temperature. Biosci Biotechnol Biochem 2003, 67:893-895.
36. Kohno K., Ohtsuki T., Suemoto Y., Inoue T., Taniguchi Y., Usui M., et al. Regulation of cytokine production by sugi allergen-pullulan conjugate. Cell Immunol 1996, 168:211-219.