Genetic variants on chromosome 8q24 and colorectal neoplasia risk: A case-control study in China and a meta-analysis of the published literature

PLoS ONE

Volumn 6, Issue 3, 2011, Pages

  Li, Mian ^a   Zhou, Yanhong ^b   Chen, Peizhan ^a   Yang, Huan ^b   Yuan, Xiaoyan ^b   Tajima, Kazuo ^c   Cao, Jia ^b   Wang, Hui ^a  

^a Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

^c AICHI CANCER CENTER HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CASE CONTROL STUDY; CHINA; CHROMOSOME 8Q; COLORECTAL CANCER; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENE LOCUS; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; HETEROZYGOTE; HOMOZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL LITERATURE; SINGLE NUCLEOTIDE POLYMORPHISM; CHROMOSOME 8; COLORECTAL TUMOR; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; META ANALYSIS; MIDDLE AGED; RISK;

ADULT; AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; CHINA; CHROMOSOMES, HUMAN, PAIR 8; COLORECTAL NEOPLASMS; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MIDDLE AGED; ODDS RATIO; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 79953046330     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0018251     Document Type: Article

References (41)

1. Jemal A, Siegel R, Xu J, Ward E, (2010) Cancer statistics, 2010. CA Cancer J Clin 60: 277-300.
2. Tenesa A, Farrington SM, Prendergast JG, Porteous ME, Walker M, et al. (2008) Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. Nat Genet 40: 631-637.
3. Xu Y, Pasche B, (2007) TGF-beta signaling alterations and susceptibility to colorectal cancer. Hum Mol Genet 16(Spec No 1): R14-20.
4. Haiman CA, Le Marchand L, Yamamato J, Stram DO, Sheng X, et al. (2007) A common genetic risk factor for colorectal and prostate cancer. Nat Genet 39: 954-956.
5. Tomlinson I, Webb E, Carvajal-Carmona L, Broderick P, Kemp Z, et al. (2007) A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21. Nat Genet 39: 984-988.
6. Zanke BW, Greenwood CM, Rangrej J, Kustra R, Tenesa A, et al. (2007) Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24. Nat Genet 39: 989-994.
7. Tomlinson IP, Webb E, Carvajal-Carmona L, Broderick P, Howarth K, et al. (2008) A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. Nat Genet 40: 623-630.
8. Jaeger E, Webb E, Howarth K, Carvajal-Carmona L, Rowan A, et al. (2008) Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk. Nat Genet 40: 26-28.
9. Broderick P, Carvajal-Carmona L, Pittman AM, Webb E, Howarth K, et al. (2007) A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk. Nat Genet 39: 1315-1317.
10. Haiman CA, Patterson N, Freedman ML, Myers SR, Pike MC, et al. (2007) Multiple regions within 8q24 independently affect risk for prostate cancer. Nat Genet 39: 638-644.
11. Poynter JN, Figueiredo JC, Conti DV, Kennedy K, Gallinger S, et al. (2007) Variants on 9p24 and 8q24 are associated with risk of colorectal cancer: results from the Colon Cancer Family Registry. Cancer Res 67: 11128-11132.
12. Berndt SI, Potter JD, Hazra A, Yeager M, Thomas G, et al. (2008) Pooled analysis of genetic variation at chromosome 8q24 and colorectal neoplasia risk. Hum Mol Genet17: 2665-2672.
13. Tuupanen S, Niittymaki I, Nousiainen K, Vanharanta S, Mecklin JP, et al. (2008) Allelic imbalance at rs6983267 suggests selection of the risk allele in somatic colorectal tumor evolution. Cancer Res 68: 14-17.
14. Ghoussaini M, Song H, Koessler T, Al Olama AA, Kote-Jarai Z, et al. (2008) Multiple loci with different cancer specificities within the 8q24 gene desert. J Natl Cancer Inst 100: 962-966.
15. Sung JJ, Lau JY, Goh KL, Leung WK, (2005) Increasing incidence of colorectal cancer in Asia: implications for screening. Lancet Oncol 6: 871-876.
16. Yang H, Zhou Y, Zhou Z, Liu J, Yuan X, et al. (2009) A novel polymorphism rs1329149 of CYP2E1 and a known polymorphism rs671 of ALDH2 of alcohol metabolizing enzymes are associated with colorectal cancer in a southwestern Chinese population. Cancer Epidemiol Biomarkers Prev 18: 2522-2527.
17. Gruber SB, Moreno V, Rozek LS, Rennerts HS, Lejbkowicz F, et al. (2007) Genetic variation in 8q24 associated with risk of colorectal cancer. Cancer Biol Ther 6: 1143-1147.
18. White KL, Sellers TA, Fridley BL, Vierkant RA, Phelan CM, et al. (2010) Variation at 8q24 and 9p24 and risk of epithelial ovarian cancer. Twin Res Hum Genet 13: 43-56.
19. Wokolorczyk D, Gliniewicz B, Sikorski A, Zlowocka E, Masojc B, et al. (2008) A range of cancers is associated with the rs6983267 marker on chromosome 8. Cancer Res 68: 9982-9986.
20. Zheng SL, Sun J, Wiklund F, Smith S, Stattin P, et al. (2008) Cumulative association of five genetic variants with prostate cancer. N Engl J Med 358: 910-919.
21. Garcia-Closas M, Lubin JH, (1999) Power and sample size calculations in case-control studies of gene-environment interactions: comments on different approaches. Am J Epidemiol 149: 689-692.
22. Lubin JH, Gail MH, (1990) On power and sample size for studying features of the relative odds of disease. Am J Epidemiol 131: 552-566.
23. Egger M, Davey Smith G, Schneider M, Minder C, (1997) Bias in meta-analysis detected by a simple, graphical test. BMJ 315: 629-634.
24. Begg CB, Mazumdar M, (1994) Operating characteristics of a rank correlation test for publication bias. Biometrics 50: 1088-1101.
25. Li L, Plummer SJ, Thompson CL, Merkulova A, Acheson LS, et al. (2008) A common 8q24 variant and the risk of colon cancer: a population-based case-control study. Cancer Epidemiol Biomarkers Prev 17: 339-342.
26. Curtin K, Lin WY, George R, Katory M, Shorto J, et al. (2009) Meta association of colorectal cancer confirms risk alleles at 8q24 and 18q21. Cancer Epidemiol Biomarkers Prev 18: 616-621.
27. Matsuo K, Suzuki T, Ito H, Hosono S, Kawase T, et al. (2009) Association between an 8q24 locus and the risk of colorectal cancer in Japanese. BMC Cancer 9: 379.
28. Schafmayer C, Buch S, Volzke H, von Schonfels W, Egberts JH, et al. (2009) Investigation of the colorectal cancer susceptibility region on chromosome 8q24.21 in a large German case-control sample. Int J Cancer 124: 75-80.
29. Middeldorp A, Jagmohan-Changur S, van Eijk R, Tops C, Devilee P, et al. (2009) Enrichment of low penetrance susceptibility loci in a Dutch familial colorectal cancer cohort. Cancer Epidemiol Biomarkers Prev 18: 3062-3067.
30. Kupfer SS, Anderson JR, Hooker S, Skol A, Kittles RA, et al. (2010) Genetic heterogeneity in colorectal cancer associations between African and European americans. Gastroenterology: 139: 1677-1685, 1685 e1671-1678.
31. von Holst S, Picelli S, Edler D, Lenander C, Dalen J, et al. (2010) Association studies on 11 published colorectal cancer risk loci. Br J Cancer 103: 575-580.
32. Xiong F, Wu C, Bi X, Yu D, Huang L, et al. (2010) Risk of genome-wide association study-identified genetic variants for colorectal cancer in a Chinese population. Cancer Epidemiol Biomarkers Prev 19: 1855-1861.
33. Hutter CM, Slattery ML, Duggan DJ, Muehling J, Curtin K, et al. (2010) Characterization of the association between 8q24 and colon cancer: gene-environment exploration and meta-analysis. BMC Cancer 10: 670.
34. Cui R, Okada Y, Jang SG, Ku JL, Park JG, et al. (2011) Common variant in 6q26-q27 is associated with distal colon cancer in an Asian population. Gut [Epub ahead of print].
35. Cicek MS, Slager SL, Achenbach SJ, French AJ, Blair HE, et al. (2009) Functional and clinical significance of variants localized to 8q24 in colon cancer. Cancer Epidemiol Biomarkers Prev 18: 2492-2500.
36. He J, Wilkens LR, Stram DO, Kolonel LN, Henderson BE, et al. (2011) Generalizability and epidemiologic characterization of eleven colorectal cancer GWAS hits in multiple populations. Cancer Epidemiol Biomarkers Prev 20: 70-81.
37. Pittman AM, Broderick P, Sullivan K, Fielding S, Webb E, et al. (2008) CASP8 variants D302H and-652 6N ins/del do not influence the risk of colorectal cancer in the United Kingdom population. Br J Cancer 98: 1434-1436.
38. Kupfer SS, Torres JB, Hooker S, Anderson JR, Skol AD, et al. (2009) Novel single nucleotide polymorphism associations with colorectal cancer on chromosome 8q24 in African and European Americans. Carcinogenesis 30: 1353-1357.
39. Niittymaki I, Kaasinen E, Tuupanen S, Karhu A, Jarvinen H, et al. (2010) Low-penetrance susceptibility variants in familial colorectal cancer. Cancer Epidemiol Biomarkers Prev 19: 1478-1483.
40. Pomerantz MM, Ahmadiyeh N, Jia L, Herman P, Verzi MP, et al. (2009) The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer. Nat Genet 41: 882-884.
41. Tuupanen S, Turunen M, Lehtonen R, Hallikas O, Vanharanta S, et al. (2009) The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling. Nat Genet 41: 885-890.