Variation at 8q24 and 9p24 and risk of epithelial ovarian cancer

Twin Research and Human Genetics

Volumn 13, Issue 1, 2010, Pages 43-56

  White, Kristin L ^a   Sellers, Thomas A ^b   Fridley, Brooke L ^a   Vierkant, Robert A ^a   Phelan, Catherine M ^b   Tsai, Ya Yu ^b   Kalli, Kimberly R ^a   Berchuck, Andrew ^c   Iversen Jr , Edwin S ^c   Hartmann, Lynn C ^a   Liebow, Mark ^a   Armasu, Sebastian ^a   Fredericksen, Zachary ^a   Larson, Melissa C ^a   Duggan, David ^d   Couch, Fergus J ^a   Schildkraut, Joellen M ^c   Cunningham, Julie M ^a   Goode, Ellen L ^a  

^a Mayo Clinic   (United States)

^b H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^c DUKE UNIVERSITY   (United States)

^d TRANSLATIONAL GENOMICS RESEARCH INSTITUTE   (United States)

Author keywords

Genome wide association study; Molecular epidemiology; Neoplasms; Polymorphisms

Indexed keywords

ADULT; ARTICLE; CANCER INVASION; CANCER RISK; CHROMOSOME 8Q; CHROMOSOME 9P; CONTROLLED STUDY; EPITHELIUM TUMOR; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENETIC RISK; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MICROARRAY ANALYSIS; NUCLEOTIDE SEQUENCE; OVARY CANCER; POPULATION STRUCTURE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; ALLELE; CASE CONTROL STUDY; CHI SQUARE DISTRIBUTION; CHROMOSOME 8; CHROMOSOME 9; CLINICAL TRIAL; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENETICS; MIDDLE AGED; MULTICENTER STUDY; OVARY TUMOR; RISK FACTOR; STATISTICAL MODEL;

ADULT; ALLELES; CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; CHROMOSOMES, HUMAN, PAIR 8; CHROMOSOMES, HUMAN, PAIR 9; FEMALE; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; LOGISTIC MODELS; MIDDLE AGED; OVARIAN NEOPLASMS; RISK FACTORS;

EID: 77953265316     PISSN: 18324274     EISSN: None     Source Type: Journal    
DOI: 10.1375/twin.13.1.43     Document Type: Article

References (43)

1. Antoniou, A., Pharoah, P. D., Narod, S., Risch, H. A., Eyfjord, J. E., Hopper, J. L., Loman, N., Olsson, H., Johannsson, O., Borg, A., Pasini, B., Radice, P., Manoukian, S., Eccles, D. M., Tang, N., Olah, E., Anton-Culver, H., Warner, E., Lubinski, J., Gronwald, J., Gorski, B., Tulinius, H., Thorlacius, S., Eerola, H., Nevanlinna, H., Syrjakoski, K., Kallioniemi, O. P., Thompson, D., Evans, C., Peto, J., Lalloo, F., Evans, D. G., & Easton, D. F. (2003). Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: A combined analysis of 22 studies. American Journal of Human Genetics, 72, 1117-1130.
2. Barrett, J. C., Fry, B., Maller, J., & Daly, M. J. (2005). Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics, 21, 263-265. (Pubitemid 40202029)
3. Cher, M. L., Bova, G. S., Moore, D. H., Small, E. J., Carroll, P. R., Pin, S. S., Epstein, J. I., Isaacs, W. B., & Jensen, R. H. (1996). Genetic alterations in untreated metastases and androgen-independent prostate cancer detected by comparative genomic hybridization and allelotyping. Cancer Research, 56, 3091-3102.
4. Cunningham, J. M., Sellers, T. A., Schildkraut, J. M., Fredericksen, Z. S., Vierkant, R. A., Kelemen, L. E., Gadre, M., Phelan, C. M., Huang, Y., Meyer, J. G., Pankratz, V. S., & Goode, E. L. (2008). Performance of amplified DNA in an Illumina GoldenGate BeadArray assay. Cancer Epidemiology Biomarkers & Prevention, 17, 1781-1789.
5. Fasching, P. A., Gayther, S., Pearce, L., Schildkraut, J. M., Goode, E., Thiel, F., Chenevix-Trench, G., Chang-Claude, J., Wang-Gohrke, S., Ramus, S., Pharoah, P., & Berchuck, A. (2009). Role of genetic polymorphisms and ovarian cancer susceptibility. Molecular Oncology, 3, 171-181.
6. Garcia-Closas, M., Hall, P., Nevanlinna, H., Pooley, K., Morrison, J., Richesson, D. A., Bojesen, S. E., Nordestgaard, B. G., Axelsson, C. K., Arias, J. I., Milne, R. L., Ribas, G., Gonzalez-Neira, A., Benitez, J., Zamora, P., Brauch, H., Justenhoven, C., Hamann, U., Ko, Y. D., Bruening, T., Haas, S., Dork, T., Schurmann, P., Hillemanns, P., Bogdanova, N., Bremer, M., Karstens, J. H., Fagerholm, R., Aaltonen, K., Aittomaki, K., von Smitten, K., Blomqvist, C., Mannermaa, A., Uusitupa, M., Eskelinen, M., Tengstrom, M., Kosma, V. M., Kataja, V., Chenevix-Trench, G., Spurdle, A. B., Beesley, J., Chen, X., Australian Ovarian Cancer Management, G., Kathleen Cuningham Foundation Consortium For Research Into Familial Breast, C., Devilee, P., van Asperen, C. J., Jacobi, C. E., Tollenaar, R. A., Huijts, P. E., Klijn, J. G., Chang-Claude, J., Kropp, S., Slanger, T., Flesch-Janys, D., Mutschelknauss, E., Salazar, R., Wang-Gohrke, S., Couch, F., Goode, E. L., Olson, J. E., Vachon, C., Fredericksen, Z. S., Giles, G. G., Baglietto, L., Severi, G., Hopper, J. L., English, D. R., Southey, M. C., Haiman, C. A., Henderson, B. E., Kolonel, L. N., Le Marchand, L., Stram, D. O., Hunter, D. J., Hankinson, S. E., Cox, D. G., Tamimi, R., Kraft, P., Sherman, M. E., Chanock, S. J., Lissowska, J., Brinton, L. A., Peplonska, B., Klijn, J. G., Hooning, M. J., Meijers-Heijboer, H., Collee, J. M., van den Ouweland, A., Uitterlinden, A. G., Liu, J., Lin, L. Y., Yuqing, L., Humphreys, K., Czene, K., Cox, A., Balasubramanian, S. P., Cross, S. S., Reed, M. W., Blows, F., Driver, K., Dunning, A., Tyrer, J., Ponder, B. A., Sangrajrang, S., Brennan, P., McKay, J., Odefrey, F., Gabrieau, V., Sigurdson, A., Doody, M., Struewing, J. P., Alexander, B., Easton, D. F., & Pharoah, P. D. (2008). Heterogeneity of breast cancer associations with five susceptibility Loci by clinical and pathological characteristics. PLoS Genetics, 4, e1000054.
7. Gayther, S. A., Song, H., Ramus, S. J., Kjaer, S. K., Whittemore, A. S., Quaye, L., Tyrer, J., Shadforth, D., Hogdall, E., Hogdall, C., Blaeker, J., DiCioccio, R., McGuire, V., Webb, P. M., Beesley, J., Green, A. C., Whiteman, D. C., Goodman, M. T., Lurie, G., Carney, M. E., Modugno, F., Ness, R. B., Edwards, R. P., Moysich, K. B., Goode, E. L., Couch, F. J., Cunningham, J. M., Sellers, T. A., Wu, A. H., Pike, M. C., Iversen, E. S., Marks, J. R., Garcia-Closas, M., Brinton, L., Lissowska, J., Peplonska, B., Easton, D. F., Jacobs, I., Ponder, B. A., Schildkraut, J., Pearce, C. L., Chenevix-Trench, G., Berchuck, A., & Pharoah, P. D. (2007). Tagging single nucleotide polymorphisms in cell cycle control genes and susceptibility to invasive epithelial ovarian cancer. Cancer Research, 67, 3027-3035.
8. Ghoussaini, M., Song, H., Koessler, T., Al Olama, A. A., Kote-Jarai, Z., Driver, K. E., Pooley, K. A., Ramus, S. J., Kjaer, S. K., Hogdall, E., DiCioccio, R. A., Whittemore, A. S., Gayther, S. A., Giles, G. G., Guy, M., Edwards, S. M., Morrison, J., Donovan, J. L., Hamdy, F. C., Dearnaley, D. P., Ardern-Jones, A. T., Hall, A. L., O'Brien, L. T., Gehr-Swain, B. N., Wilkinson, R. A., Brown, P. M., Hopper, J. L., Neal, D. E., Pharoah, P. D., Ponder, B. A., Eeles, R. A., Easton, D. F., & Dunning, A. M. (2008). Multiple loci with different cancer specificities within the 8q24 gene desert. Journal of the National Cancer Institute, 100, 962-966.
9. Goode, E. L., Fridley, B. L., Vierkant, R. A., Cunningham, J. M., Phelan, C. M., Anderson, S., Rider, D. N., White, K. L., Pankratz, V. S., Song, H., Hogdall, E., Kjaer, S. K., Whittemore, A. S., DiCioccio, R., Ramus, S. J., Gayther, S. A., Schildkraut, J. M., Pharaoh, P. P., & Sellers, T. A. (2009). Candidate gene analysis using imputed genotypes: cell cycle single-nucleotide polymorphisms and ovarian cancer risk. Cancer Epidemiology Biomarkers & Prevention, 18, 935-944.
10. Gruber, S. B., Moreno, V., Rozek, L. S., Rennerts, H. S., Lejbkowicz, F., Bonner, J. D., Greenson, J. K., Giordano, T. J., Fearson, E. R., & Rennert, G. (2007). Genetic variation in 8q24 associated with risk of colorectal cancer. Cancer Biology and Therapy, 6, 1143-1147. (Pubitemid 351574969)
11. Gudmundsson, J., Sulem, P., Manolescu, A., Amundadottir, L. T., Gudbjartsson, D., Helgason, A., Rafnar, T., Bergthorsson, J. T., Agnarsson, B. A., Baker, A., Sigurdsson, A., Benediktsdottir, K. R., Jakobsdottir, M., Xu, J., Blondal, T., Kostic, J., Sun, J., Ghosh, S., Stacey, S. N., Mouy, M., Saemundsdottir, J., Backman, V. M., Kristjansson, K., Tres, A., Partin, A. W., Albers-Akkers, M. T., Godino-Ivan Marcos, J., Walsh, P. C., Swinkels, D. W., Navarrete, S., Isaacs, S. D., Aben, K. K., Graif, T., Cashy, J., Ruiz-Echarri, M., Wiley, K. E., Suarez, B. K., Witjes, J. A., Frigge, M., Ober, C., Jonsson, E., Einarsson, G. V., Mayordomo, J. I., Kiemeney, L. A., Isaacs, W. B., Catalona, W. J., Barkardottir, R. B., Gulcher, J. R., Thorsteinsdottir, U., Kong, A., & Stefansson, K. (2007). Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. Nature Genetics, 39, 631-637.
12. Haiman, C. A., Patterson, N., Freedman, M. L., Myers, S. R., Pike, M. C., Waliszewska, A., Neubauer, J., Tandon, A., Schirmer, C., McDonald, G. J., Greenway, S. C., Stram, D. O., Le Marchand, L., Kolonel, L. N., Frasco, M., Wong, D., Pooler, L. C., Ardlie, K., Oakley-Girvan, I., Whittemore, A. S., Cooney, K. A., John, E. M., Ingles, S. A., Altshuler, D., Henderson, B. E., & Reich, D. (2007). Multiple regions within 8q24 independently affect risk for prostate cancer. Nature Genetics, 39, 638-644.
13. Harismendy, O., & Frazer, K. A. (2009). Elucidating the role of 8q24 in colorectal cancer. Nature Genetics, 41, 868-869.
14. Kelemen, L. E., Sellers, T. A., Schildkraut, J. M., Cunningham, J. M., Vierkant, R. A., Pankratz, V. S., Fredericksen, Z. S., Gadre, M. K., Rider, D. N., Liebow, M., & Goode, E. L. (2008). Genetic variation in the one-carbon transfer pathway and ovarian cancer risk. Cancer Research, 68, 2498-2506. (Pubitemid 351521826)
15. Kiemeney, L. A., Thorlacius, S., Sulem, P., Geller, F., Aben, K. K., Stacey, S. N., Gudmundsson, J., Jakobsdottir, M., Bergthorsson, J. T., Sigurdsson, A., Blondal, T., Witjes, J. A., Vermeulen, S. H., Hulsbergen-van de Kaa, C. A., Swinkels, D. W., Ploeg, M., Cornel, E. B., Vergunst, H., Thorgeirsson, T. E., Gudbjartsson, D., Gudjonsson, S. A., Thorleifsson, G., Kristinsson, K. T., Mouy, M., Snorradottir, S., Placidi, D., Campagna, M., Arici, C., Koppova, K., Gurzau, E., Rudnai, P., Kellen, E., Polidoro, S., Guarrera, S., Sacerdote, C., Sanchez, M., Saez, B., Valdivia, G., Ryk, C., de Verdier, P., Lindblom, A., Golka, K., Bishop, D. T., Knowles, M. A., Nikulasson, S., Petursdottir, V., Jonsson, E., Geirsson, G., Kristjansson, B., Mayordomo, J. I., Steineck, G., Porru, S., Buntinx, F., Zeegers, M. P., Fletcher, T., Kumar, R., Matullo, G., Vineis, P., Kiltie, A. E., Gulcher, J. R., Thorsteinsdottir, U., Kong, A., Rafnar, T., & Stefansson, K. (2008). Sequence variant on 8q24 confers susceptibility to urinary bladder cancer. Nature Genetics, 40, 1307-1312.
16. Morch, L. S., Lokkegaard, E., Andreasen, A. H., Kruger-Kjaer, S., & Lidegaard, O. (2009). Hormone Therapy and Ovarian Cancer. JAMA, 302, 298-305.
17. Oliphant, A., Barker, D. L., Stuelpnagel, J. R., & Chee, M. S. (2002). BeadArray technology: enabling an accurate, cost-effective approach to high-throughput genotyping. Biotechniques, Suppl, 56-58, 60-51.
18. Pearce, C. L., Wu, A. H., Gayther, S. A., Bale, A. E., Beck, P. A., Beesley, J., Chanock, S., Cramer, D. W., Dicioccio, R., Edwards, R., Fredericksen, Z. S., Garcia-Closas, M., Goode, E. L., Green, A. C., Hartmann, L. C., Hogdall, E., Kjaer, S. K., Lissowska, J., McGuire, V., Modugno, F., Moysich, K., Ness, R. B., Ramus, S. J., Risch, H. A., Sellers, T. A., Song, H., Stram, D. O., Terry, K. L., Webb, P. M., Whiteman, D. C., Whittemore, A. S., Zheng, W., Pharoah, P. D., Chenevix-Trench, G., Pike, M. C., Schildkraut, J., Berchuck, A., & on behalf of the Ovarian Cancer Association Consortium (OCAC). (2008). Progesterone receptor variation and risk of ovarian cancer is limited to the invasive endometrioid subtype: results from the ovarian cancer association consortium pooled analysis. British Journal of Cancer, 98, 282-288.
19. Pharoah, P. D., & Ponder, B. A. (2002). The genetics of ovarian cancer. Best Practice and Research: Clinical Obstetrics and Gynaecology, 16, 449-468.
20. Pomerantz, M. M., Ahmadiyeh, N., Jia, L., Herman, P., Verzi, M. P., Doddapaneni, H., Beckwith, C. A., Chan, J. A., Hills, A., Davis, M., Yao, K., Kehoe, S. M., Lenz, H. J., Haiman, C. A., Yan, C., Henderson, B. E., Frenkel, B., Barretina, J., Bass, A., Tabernero, J., Baselga, J., Regan, M. M., Manak, J. R., Shivdasani, R., Coetzee, G. A., & Freedman, M. L. (2009). The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer. Nature Genetics, 41, 882-884.
21. Poynter, J. N., Figueiredo, J. C., Conti, D. V., Kennedy, K., Gallinger, S., Siegmund, K. D., Casey, G., Thibodeau, S. N., Jenkins, M. A., Hopper, J. L., Byrnes, G. B., Baron, J. A., Goode, E. L., Tiirikainen, M., Lindor, N., Grove, J., Newcomb, P., Jass, J., Young, J., Potter, J. D., Haile, R. W., Duggan, D. J., & Le Marchand, L. (2007). Variants on 9p24 and 8q24 are associated with risk of colorectal cancer: results from the Colon Cancer Family Registry. Cancer Research, 67, 11128-11132.
22. Price, A. L., Patterson, N. J., Plenge, R. M., Weinblatt, M. E., Shadick, N. A., & Reich, D. (2006). Principal components analysis corrects for stratification in genome-wide association studies. Nature Genetics, 38, 904-909. (Pubitemid 44141658)
23. Ramus, S. J., Harrington, P. A., Pye, C., DiCioccio, R. A., Cox, M. J., Garlinghouse-Jones, K., Oakley-Girvan, I., Jacobs, I. J., Hardy, R. M., Whittemore, A. S., Ponder, B. A., Piver, M. S., Pharoah, P. D., & Gayther, S. A. (2007). Contribution of BRCA1 and BRCA2 mutations to inherited ovarian cancer. Human Mutation, 28, 1207-1215.
24. Salinas, C. A., Kwon, E., Carlson, C. S., Koopmeiners, J. S., Feng, Z., Karyadi, D. M., Ostrander, E. A., & Stanford, J. L. (2008). Multiple independent genetic variants in the 8q24 region are associated with prostate cancer risk. Cancer Epidemiology Biomarkers & Prevention, 17, 1203-1213.
25. Schildkraut, J. M., Goode, E. L., Clyde, M. A., Iversen, E. S., Moorman, P. G., Berchuck, A., Marks, J. R., Lissowska, J., Brinton, L., Peplonska, B., Cunningham, J. M., Vierkant, R. A., Rider, D. N., Chenevix-Trench, G., Webb, P. M., Beesley, J., Chen, X., Phelan, C., Sutphen, R., Sellers, T. A., Pearce, L., Wu, A. H., Van Den Berg, D., Conti, D., Elund, C. K., Anderson, R., Goodman, M. T., Lurie, G., Carney, M. E., Thompson, P. J., Gayther, S. A., Ramus, S. J., Jacobs, I., Kruger Kjaer, S., Hogdall, E., Blaakaer, J., Hogdall, C., Easton, D. F., Song, H., Pharoah, P. D., Whittemore, A. S., McGuire, V., Quaye, L., Anton-Culver, H., Ziogas, A., Terry, K. L., Cramer, D. W., Hankinson, S. E., Tworoger, S. S., Calingaert, B., Chanock, S., Sherman, M., & Garcia-Closas, M. (2009). Single nucleotide polymorphisms in the TP53 region and susceptibility to invasive epithelial ovarian cancer. Cancer Research, 69, 2349-2357.
26. Schumacher, F. R., Feigelson, H. S., Cox, D. G., Haiman, C. A., Albanes, D., Buring, J., Calle, E. E., Chanock, S. J., Colditz, G. A., Diver, W. R., Dunning, A. M., Freedman, M. L., Gaziano, J. M., Giovannucci, E., Hankinson, S. E., Hayes, R. B., Henderson, B. E., Hoover, R. N., Kaaks, R., Key, T., Kolonel, L. N., Kraft, P., Le Marchand, L., Ma, J., Pike, M. C., Riboli, E., Stampfer, M. J., Stram, D. O., Thomas, G., Thun, M. J., Travis, R., Virtamo, J., Andriole, G., Gelmann, E., Willett, W. C., & Hunter, D. J. (2007). A Common 8q24 Variant in Prostate and Breast Cancer from a Large Nested Case-Control Study. Cancer Research, 67, 2951-2956.
27. Sellers, T. A., Schildkraut, J. M., Pankratz, V. S., Vierkant, R. A., Fredericksen, Z. S., Olson, J. E., Cunningham, J. M., Taylor, W., Liebow, M., McPherson, C. P., Hartmann, L. C., Pal, T., & Adjei, A. A. (2005). Estrogen bioactivation, genetic polymorphisms, and ovarian cancer. Cancer Epidemiology Biomarkers & Prevention, 14, 2536-2543. (Pubitemid 41752712)
28. Setiawan, V. W., Ursin, G., Horn-Ross, P. L., Van Den Berg, D., Le Marchand, L., Henderson, B. E., Bernstein, L., & Haiman, C. A. (2007). Germ line variation at 8q24 and endometrial cancer risk. Cancer Epidemiology Biomarkers & Prevention, 16, 2166-2168. (Pubitemid 47621197)
29. Sole, X., Hernandez, P., de Heredia, M. L., Armengol, L., Rodriguez-Santiago, B., Gomez, L., Maxwell, C. A., Aguilo, F., Condom, E., Abril, J., Perez-Jurado, L., Estivill, X., Nunes, V., Capella, G., Gruber, S. B., Moreno, V., & Pujana, M. A. (2008). Genetic and genomic analysis modeling of germline c-MYC overexpression and cancer susceptibility. BMC Genomics, 9, 12.
30. Song, H., Ramus, S. J., Kjaer, S. K., DiCioccio, R. A., Chenevix-Trench, G., Pearce, C. L., Hogdall, E., Whittemore, A. S., McGuire, V., Hogdall, C., Blaakaer, J., Wu, A. H., Van Den Berg, D. J., Stram, D. O., Menon, U., Gentry-Maharaj, A., Jacobs, I. J., Webb, P. M., Beesley, J., Chen, X., Rossing, M. A., Doherty, J. A., Chang-Claude, J., Wang-Gohrke, S., Goodman, M. T., Lurie, G., Thompson, P. J., Carney, M. E., Ness, R. B., Moysich, K., Goode, E. L., Vierkant, R. A., Cunningham, J. M., Anderson, S., Schildkraut, J. M., Berchuck, A., Iversen, E. S., Moorman, P. G., Garcia-Closas, M., Chanock, S., Lissowska, J., Brinton, L., Anton-Culver, H., Ziogas, A., Brewster, W. R., Ponder, B. A., Easton, D. F., Gayther, S. A., & Pharoah, P. D. (2009). Association between invasive ovarian cancer susceptibility and 11 best candidate SNPs from breast cancer genome-wide association study. Human Molecular Genetics, 18, 2297-2304.
31. Song, H., Ramus, S. J., Quaye, L., Dicioccio, R. A., Tyrer, J., Lomas, E., Shadforth, D., Hogdall, E., Hogdall, C., McGuire, V., Whittemore, A. S., Easton, D. F., Ponder, B. A., Kjaer, S. K., Pharoah, P. D., & Gayther, S. A. (2006). Common variants in mismatch repair genes and risk of invasive ovarian cancer. Carcinogenesis, 27, 2235-2242. (Pubitemid 44644812)
32. Song, H., Ramus, S. J., Tyrer, J., Bolton, K. L., Gentry-Maharaj, A., Wozniak, E., Anton-Culver, H., Chang-Claude, J., Cramer, D. W., Dicioccio, R., Dork, T., Goode, E. L., Goodman, M. T., Schildkraut, J. M., Sellers, T., Baglietto, L., Beckmann, M. W., Beesley, J., Blaakaer, J., Carney, M. E., Chanock, S., Chen, Z., Cunningham, J. M., Dicks, E., Doherty, J. A., Durst, M., Ekici, A. B., Fenstermacher, D., Fridley, B. L., Giles, G., Gore, M. E., De Vivo, I., Hillemanns, P., Hogdall, C., Hogdall, E., Iversen, E. S., Jacobs, I. J., Jakubowska, A., Li, D., Lissowska, J., Lubinski, J., Lurie, G., McGuire, V., McLaughlin, J., Medrek, K., Moorman, P. G., Moysich, K., Narod, S., Phelan, C., Pye, C., Risch, H., Runnebaum, I. B., Severi, G., Southey, M., Stram, D. O., Thiel, F. C., Terry, K. L., Tsai, Y. Y., Tworoger, S. S., Van Den Berg, D. J., Vierkant, R. A., Wang-Gohrke, S., Webb, P. M., Wilkens, L. R., Wu, A. H., Yang, H., Brewster, W., Ziogas, A., Houlston, R., Tomlinson, I., Whittemore, A. S., Rossing, M. A., Ponder, B. A., Pearce, C. L., Ness, R. B., Menon, U., Kjaer, S. K., Gronwald, J., Garcia-Closas, M., Fasching, P. A., Easton, D. F., Chenevix-Trench, G., Berchuck, A., Pharoah, P. D., & Gayther, S. A. (2009). A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2. Nature Genetics.
33. Suuriniemi, M., Agalliu, I., Schaid, D. J., Johanneson, B., McDonnell, S. K., Iwasaki, L., Stanford, J. L., & Ostrander, E. A. (2007). Confirmation of a positive association between prostate cancer risk and a locus at chromosome 8q24. Cancer Epidemiology Biomarkers & Prevention, 16, 809-814. (Pubitemid 46650586)
34. Tenesa, A., Farrington, S. M., Prendergast, J. G., Porteous, M. E., Walker, M., Haq, N., Barnetson, R. A., Theodoratou, E., Cetnarskyj, R., Cartwright, N., Semple, C., Clark, A. J., Reid, F. J., Smith, L. A., Kavoussanakis, K., Koessler, T., Pharoah, P. D., Buch, S., Schafmayer, C., Tepel, J., Schreiber, S., Volzke, H., Schmidt, C. O., Hampe, J., Chang-Claude, J., Hoffmeister, M., Brenner, H., Wilkening, S., Canzian, F., Capella, G., Moreno, V., Deary, I. J., Starr, J. M., Tomlinson, I. P., Kemp, Z., Howarth, K., Carvajal-Carmona, L., Webb, E., Broderick, P., Vijayakrishnan, J., Houlston, R. S., Rennert, G., Ballinger, D., Rozek, L., Gruber, S. B., Matsuda, K., Kidokoro, T., Nakamura, Y., Zanke, B. W., Greenwood, C. M., Rangrej, J., Kustra, R., Montpetit, A., Hudson, T. J., Gallinger, S., Campbell, H., & Dunlop, M. G. (2008). Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. Nature Genetics, 40, 631-637.
35. Tuupanen, S., Turunen, M., Lehtonen, R., Hallikas, O., Vanharanta, S., Kivioja, T., Bjorklund, M., Wei, G., Yan, J., Niittymaki, I., Mecklin, J. P., Jarvinen, H., Ristimaki, A., Di-Bernardo, M., East, P., Carvajal-Carmona, L., Houlston, R. S., Tomlinson, I., Palin, K., Ukkonen, E., Karhu, A., Taipale, J., & Aaltonen, L. A. (2009). The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling. Nature Genetics, 41, 885-890.
36. van Duin, M., van Marion, R., Vissers, K., Watson, J. E., van Weerden, W. M., Schroder, F. H., Hop, W. C., van der Kwast, T. H., Collins, C., & van Dekken, H. (2005). High-resolution array comparative genomic hybridization of chromosome arm 8q: evaluation of genetic progression markers for prostate cancer. Genes, Chromosomes and Cancer, 44, 438-449.
37. Visakorpi, T., Kallioniemi, A. H., Syvanen, A. C., Hyytinen, E. R., Karhu, R., Tammela, T., Isola, J. J., & Kallioniemi, O. P. (1995). Genetic changes in primary and recurrent prostate cancer by comparative genomic hybridization. Cancer Research, 55, 342-347.
38. Weir, B. S. (1996). Genetic data analysis II: methods for discrete population genetic data. Sunderland MA: Sinauer Associates, Inc.
39. Witte, J. S. (2007). Multiple prostate cancer risk variants on 8q24. Nature Genetics, 39, 579-580. (Pubitemid 46676095)
40. Wokolorczyk, D., Gliniewicz, B., Sikorski, A., Zlowocka, E., Masojc, B., Debniak, T., Matyjasik, J., Mierzejewski, M., Medrek, K., Oszutowska, D., Suchy, J., Gronwald, J., Teodorczyk, U., Huzarski, T., Byrski, T., Jakubowska, A., Gorski, B., van de Wetering, T., Walczak, S., Narod, S. A., Lubinski, J., & Cybulski, C. (2008). A range of cancers is associated with the rs6983267 marker on chromosome 8. Cancer Research, 68, 9982-9986.
41. Wokolorczyk, D., Lubinski, J., Narod, S. A., & Cybulski, C. (2009). Genetic heterogeneity of 8q24 region in susceptibility to cancer. Journal of the National Cancer Institute, 101, 278-279.
42. Yeager, M., Orr, N., Hayes, R. B., Jacobs, K. B., Kraft, P., Wacholder, S., Minichiello, M. J., Fearnhead, P., Yu, K., Chatterjee, N., Wang, Z., Welch, R., Staats, B. J., Calle, E. E., Feigelson, H. S., Thun, M. J., Rodriguez, C., Albanes, D., Virtamo, J., Weinstein, S., Schumacher, F. R., Giovannucci, E., Willett, W. C., Cancel-Tassin, G., Cussenot, O., Valeri, A., Andriole, G. L., Gelmann, E. P., Tucker, M., Gerhard, D. S., Fraumeni, J. F., Jr., Hoover, R., Hunter, D. J., Chanock, S. J., & Thomas, G. (2007). Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. Nature Genetics, 39, 645-649.
43. Zanke, B. W., Greenwood, C. M., Rangrej, J., Kustra, R., Tenesa, A., Farrington, S. M., Prendergast, J., Olschwang, S., Chiang, T., Crowdy, E., Ferretti, V., Laflamme, P., Sundararajan, S., Roumy, S., Olivier, J. F., Robidoux, F., Sladek, R., Montpetit, A., Campbell, P., Bezieau, S., O'Shea A, M., Zogopoulos, G., Cotterchio, M., Newcomb, P., McLaughlin, J., Younghusband, B., Green, R., Green, J., Porteous, M. E., Campbell, H., Blanche, H., Sahbatou, M., Tubacher, E., Bonaiti-Pellie, C., Buecher, B., Riboli, E., Kury, S., Chanock, S. J., Potter, J., Thomas, G., Gallinger, S., Hudson, T. J., & Dunlop, M. G. (2007). Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24. Nature Genetics, 39, 989-994. (Pubitemid 47185183)