Effect of non-Newtonian and pulsatile blood flow on mass transport in the human aorta

Journal of Biomechanics

Volumn 44, Issue 6, 2011, Pages 1123-1131

  Liu, Xiao ^a   Fan, Yubo ^a   Deng, Xiaoyan ^a   Zhan, Fan ^a  

^a BEIHANG UNIVERSITY   (China)

Author keywords

Atherosclerosis; Low density lipoprotein; Non Newtonian; Oxygen transport; Pulsatile flow

Indexed keywords

AORTA MODEL; ATHEROSCLEROSIS; BLOOD FLOW; DIFFUSIVITIES; FLOW CONDITION; IN-VIVO; LOW DENSITY LIPOPROTEINS; LOW OXYGEN; MASS TRANSPORT; MRI IMAGE; NEWTONIANS; NON-NEWTONIAN; NON-NEWTONIAN BEHAVIORS; NON-NEWTONIAN MODELS; OXYGEN FLUXES; OXYGEN TRANSPORT; PULSATILE BLOOD FLOW; SHEAR THINNING; WALL SHEAR STRESS;

BLOOD; BLOOD VESSELS; CONCENTRATION (PROCESS); DISEASES; FLOW SIMULATION; HEMODYNAMICS; MAGNETIC RESONANCE IMAGING; OXYGEN; PULSATILE FLOW; SHEAR FLOW; STEADY FLOW;

NON NEWTONIAN FLOW;

LOW DENSITY LIPOPROTEIN;

ADULT; AORTA FLOW; ARTICLE; ATHEROGENESIS; BLOOD VISCOSITY; COMPUTER MODEL; CONTROLLED STUDY; DIFFUSION COEFFICIENT; HEMODYNAMIC MONITORING; HUMAN; HUMAN EXPERIMENT; IN VIVO STUDY; INTERMETHOD COMPARISON; ISCHEMIA; LIPOPROTEIN BLOOD LEVEL; MALE; NORMAL DISTRIBUTION; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OXYGEN TRANSPORT; PRIORITY JOURNAL; PROCESS MODEL; PULSATILE FLOW; SHEAR STRESS; STATISTICAL MODEL; STEADY STATE; SURFACE PROPERTY; THREE DIMENSIONAL IMAGING;

AORTA; ATHEROSCLEROSIS; BIOLOGICAL TRANSPORT; BLOOD FLOW VELOCITY; HUMANS; LIPOPROTEINS, LDL; MODELS, CARDIOVASCULAR; OXYGEN;

EID: 79953028211     PISSN: 00219290     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2011.01.024     Document Type: Article

References (42)

1. Ai L., Vafai K. A coupling model for macromolecule transport in a stenosed arterial wall. International Journal of Heat and Mass Transfer 2006, 49:1568-1591.
2. Caro C.G., Fitz-Gerald J.M., Schroter R.C. Atheroma and arterial wall shear. Observation, correlation, and proposal for a shear dependent mass transfer mechanism for atherogenesis. Proceedings of the Royal Society B: Biological Sciences 1971, 117:109-159.
3. Chen J., Lu X.Y. Numerical investigation of the non-Newtonian pulsatile blood flow in a bifurcation model with a non-planar branch. Journal of Biomechanics 2006, 39:818-832.
4. Chen Z., Fan Y., Deng X., Xu Z. Swirling flow can suppress flow disturbances in endovascular stents: a numerical study. Journal of the American Society for Artificial Internal Organs 2009, 55:543-549.
5. Deng X., Marois Y., How T., Merhi Y., King M., Guidoin R., Karino T. Luminal surface concentration of lipoprotein (LDL) and its effect on the wall uptake of cholesterol by canine carotid arteries. Journal of Vascular Surgery 1995, 21:135-145.
6. Friedman M.H. Geometric risk factors for arteriosclerosis. Johns Hopkins APL Technical Digest (Appl. Phys. Lab.) 1983, 4:85-95.
7. Hope T.A., Markl M., Wigström L., Alley M.T., Miller D.C., Herfkens R.J. Comparison of flow patterns in ascending aortic aneurysms and volunteers using four-dimensional magnetic resonance velocity mapping. Journal of Magnetic Resonance Imaging 2007, 26:1471-1479.
8. Hultén L.M., Levin M. The role of hypoxia in atherosclerosis. Current Opinion in Lipidology 2009, 20:409-414.
9. Jin S., Oshinski J., Giddens D.P. Effects of wall motion and compliance on flow patterns in the ascending aorta. Journal of Biomechanical Engineering 2003, 125:347-354.
10. Johnston B.M., Johnston P.R., Corney S., Kilpatrick D. Non-Newtonian blood flow in human right coronary arteries: steady state simulations. Journal of Biomechanics 2004, 37:709-720.
11. Khakpour M., Vafai k. A comprehensive analytical solution of macromolecular transport within an artery. International Journal of Heat and Mass Transfer 2008, 51:2905-2913.
12. Khakpour M., Vafai K. Critical assessment of arterial transport models. International Journal of Heat and Mass Transfer 2008, 51:807-822.
13. Khakpour M., Vafai k. Effects of gender-related geometrical characteristics of aorta-iliac bifurcation on hemodynamics and macromolecule concentration distribution. International Journal of Heat and Mass Transfer 2008, 51:5542-5551.
14. Kilner P.J., Yang G.Z., Mohiaddin R.H., Firmin D.N., Longmore D.B. Helical and retrograde secondary flow patterns in the aortic arch studied by three-directional magnetic resonance velocity mapping. Circulation 1993, 88:2235-2247.
15. Ku D.N., Giddens D.P., Zarins C.K., Glagov S. Pulsatile flow and atherosclerosis in the human carotid bifurcation. Positive correlation between plaque location and low oscillating shear stress. Arteriosclerosis 1985, 5:293-302.
16. Lee S.W., Steinman D.A. On the relative importance of rheology for image-based CFD models of the carotid bifurcation. Journal of Biomechanical Engineering 2007, 129:273-278.
17. Liu X., Fan Y., Deng X. Effect of spiral flow on the transport of oxygen in the aorta: a numerical study. Annals of Biomedical Engineering 2010, 38:917-926.
18. Liu X., Pu F., Fan Y., Deng X., Li D., Li S. A numerical study on the flow of blood and the transport of LDL in the human aorta: the physiological significance of the helical flow in the aortic arch. American Journal of Physiology-Heart and Circulatory Physiology 2009, 297:H163-H170.
19. Matsushita H., Morishita R., Nata T., Aoki M., Nakagami H., Taniyama Y., Yamamoto K., Higaki J., Yasufumi K., Ogihara T. Hypoxia-induced endothelial apoptosis through nuclear factor-kappaB (NF-kappaB)-mediated bcl-2 suppression: in vivo evidence of the importance of NF-kappaB in endothelial cell regulation. Circulation Research 2000, 12:974-981.
20. Morbiducci U., Ponzini R., Grigioni M., Redaelli A. Helical flow as fluid dynamic signature for atherogenesis risk in aortocoronary bypass. A numeric study. Journal of Biomechanics 2007, 2007(40):519-534.
21. Morbiducci U., Ponzini R., Rizzo G., Cadioli M., Esposito A., De Cobelli F., Del Maschio A., Montevecchi F.M., Redaelli A. In vivo quantification of helical blood flow in human aorta by time-resolved three-dimensional cine phase contrast magnetic resonance imaging. Annals of Biomedical Engineering 2009, 37:516-531.
22. Morbiducci U., Gallo D., Massai D., Consolo F., Ponzini R., Antiga L., Bignardi C., Deriu M.A., Redaelli A. Outflow conditions for image-based hemodynamic models of the carotid bifurcation: implications for indicators of abnormal flow. Journal of Biomechanical Engineering 2010, 132:910051-9100511.
23. Morbiducci U., Gallo D., Ponzini R., Massai D., Antiga L., Montevecchi F.M., Redaelli A. Quantitative analysis of bulk flow in image-based hemodynamic models of the carotid bifurcation: the influence of outflow conditions as test case. Annals of Biomedical Engineering 2010, 38:3688-3705.
24. Morbiducci, U., Ponzini, R., Rizzo, G., Cadioli, M., Esposito, A., Montevecchi, F.M., Redaelli, A.. Mechanistic insight into the physiological relevance of helical blood flow in the human aorta: an in vivo study. Biomechanics and Modeling in Mechanobiology, in press, DOI: 10.1007/s10237-010-0238-2.
25. Moyle K.R., Antiga L., Steinman D.A. Inlet conditions for image-based CFD models of the carotid bifurcation: is it reasonable to assume fully-developed flow?. Journal of Biomechanical Engineering 2006, 128:371-379.
26. O'Callaghan S., Walsh M., McGloughlin T. Numerical modelling of Newtonian and non-Newtonian representation of blood in a distal end-to-side vascular bypass graft anastomosis. Medical Engineering and Physics 2006, 28:70-74.
27. Ogawa S., Gerlach H., Esposito C., Pasagian-Macaulay A., Brett J., Stern D. Hypoxia modulates the barrier and coagulant function of cultured bovine endothelium. Increased monolayer permeability and induction of procoagulant properties. The Journal of Clinical Investigation 1990, 85:1090-1098.
28. Okamoto R., Hatani M., Tsukitani M., Suehiro A., Fujino M., Imai N., Takano S., Watanabe Y., Fukuzaki H. The effect of oxygen on the development of atherosclerosis in WHHL rabbits. Atherosclerosis 1983, 47:47-53.
29. Rappitsch G., Perktold K. Pulsatile albumin transport in large arteries: a numerical simulation study. Journal of Biomechanical Engineering 1996, 118:511-519.
30. Santilli S.M., Stevens R.B., Anderson J.G., Payne W.D., Caldwell M.D. Transarterial wall oxygen gradients at the dog carotid bifurcation. American Journal of Physiology 1995, 268:H155-161.
31. Schneiderman G., Mockros L.F., Goldstick T.K. Effect of pulsatility on oxygen transport to the human arterial wall. Journal of Biomechanics 1982, 15:849-858.
32. Shahcheraghi N., Dwyer H.A., Cheer A.Y., Barakat A.I., Rutaganira T. Unsteady and three-dimensional simulation of blood flow in the human aortic arch. Journal of Biomechanical Engineering 2002, 124:378-387.
33. Stary H.C. Evolution and progression of atherosclerotic lesions in coronary arteries of children and young adults. Arteriosclerosis 1989, 9(Suppl. 1):I19-32.
34. Sun A., Fan Y., Deng X. Numerical investigation of blood flow in the distal end of an axis-deviated arterial bypass model. Biorheology 2009, 46:83-92.
35. Sun N., Wood N.B., Hughes A.D., Thom S.A.M., Xu X.Y. Fluid-wall modelling of mass transfer in an axisymmetric stenosis: effects of shear-dependent transport properties. Annals of Biomedical Engineering 2006, 34:1119-1128.
36. Tada S., Tarbell J.M. Oxygen mass transport in a compliant carotid bifurcation model. Annals of Biomedical Engineering 2006, 34:1389-1399.
37. Tarbell J.M. Mass transport in arteries and the localization of atherosclerosis. Annual Review of Biomedical Engineering 2003, 5:79-118.
38. Thomas J.B., Milner J.S., Rutt B.K., Steinman D.A. Reproducibility of image-based computational fluid dynamics models of the human carotid bifurcation. Annals of Biomedical Engineering 2003, 31:132-141.
39. Wang G., Deng X., Guidoin R. Concentration polarization of macromolecules in canine carotid arteries and its implication for the localization of atherogenesis. Journal of Biomechanics 2003, 36:45-51.
40. Yang N., Vafai K. Modeling of low-density lipoprotein (LDL) transport in the artery-effects of hypertension. International Journal of Heat and Mass Transfer 2006, 49:850-867.
41. Yang N., Vafai k. Low density lipoprotein (LDL) transport in an artery-a simplified analytical solution. International Journal of Heat and Mass Transfer 2008, 51:497-505.
42. Zhan F., Fan Y., Deng X. Swirling flow created in a glass tube suppressed platelet adhesion to the surface of the tube: its implication in the design of small-caliber arterial grafts. Thrombosis Research 2010, 125:413-418.