Cyclic stretch of human lung cells induces an acidification and promotes bacterial growth

American Journal of Respiratory Cell and Molecular Biology

Volumn 38, Issue 3, 2008, Pages 362-370

  Pugin, Jérôme ^a,b   Dunn Siegrist, Irène ^a,b   Dufour, Julien ^a,b   Tissières, Pierre ^a,b   Charles, Pierre Emmanuel ^a,b   Comte, Rachel ^a,b  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^b UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

Cyclic stretch; Lactic acidosis; Pulmonary epithelial cells; Sodium pumps; Ventilator associated pneumonia

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); LACTIC ACID; OUABAIN; ANTIMETABOLITE; CYCLIC AMP; DEOXYGLUCOSE; FORMAZAN; GLUCOSE; LACTIC ACID DERIVATIVE; OXAMIC ACID;

ACIDIFICATION; ALKALINIZATION; ARTICLE; ARTIFICIAL VENTILATION; BACTERIAL GROWTH; BACTERIUM CULTURE; CELL ACTIVITY; CELL CYLIC STRETCH; ESCHERICHIA COLI; FIBROBLAST; HUMAN; HUMAN CELL; LUNG ALVEOLUS CELL; MACROPHAGE; NONHUMAN; PH; SUPERNATANT; VENTILATOR ASSOCIATED PNEUMONIA; ACIDOSIS; BACTERIAL COUNT; BIOLOGICAL MODEL; CELL LINE; CELL SURVIVAL; CHEMISTRY; COMPARATIVE STUDY; CULTURE MEDIUM; CYTOLOGY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; EPITHELIUM CELL; ESCHERICHIA COLI K 12; GROWTH, DEVELOPMENT AND AGING; LACTIC ACIDOSIS; LUNG ALVEOLUS; MECHANICAL STRESS; METABOLISM; TIME;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; MURINAE; STROPHANTHUS GRATUS;

ACIDOSIS; ACIDOSIS, LACTIC; ANTIMETABOLITES; CELL LINE; CELL SURVIVAL; COLONY COUNT, MICROBIAL; CULTURE MEDIA, CONDITIONED; CYCLIC AMP; DEOXYGLUCOSE; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; ESCHERICHIA COLI K12; FORMAZANS; GLUCOSE; HUMANS; HYDROGEN-ION CONCENTRATION; LACTATES; LACTIC ACID; MODELS, BIOLOGICAL; OUABAIN; OXAMIC ACID; PNEUMONIA, VENTILATOR-ASSOCIATED; PULMONARY ALVEOLI; RESPIRATION, ARTIFICIAL; SODIUM-POTASSIUM-EXCHANGING ATPASE; STRESS, MECHANICAL; TIME FACTORS;

EID: 40649097757     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2007-0114OC     Document Type: Article

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