A robust in vivo positive-readout system for monitoring siRNA delivery to xenograft tumors

RNA

Volumn 17, Issue 4, 2011, Pages 603-612

  Lin, Xiaoyu ^a   Li, Leiming ^a   Wang, Rongqi ^a   Wilcox, Denise ^a   Zhao, Xiaobin ^a   Song, Jingfeng ^a   Huang, Xiaoli ^a   Hansen, T Matthew ^a   Dande, Prasad ^a   Wada, Carol ^a   Hubbard, Robert D ^a   Kohlbrenner, William M ^a   Fesik, Stephen W ^a   Shen, Yu ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

Cancer; Delivery; RNAi; siRNA; Therapy

Indexed keywords

BETA GALACTOSIDASE; LIPID NANOPARTICLE; LIPOSOME; LUCIFERASE; NANOPARTICLE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL MODEL; ARTICLE; BRAIN TUMOR; BREAST CANCER; CANCER THERAPY; CONTROLLED STUDY; DRUG FORMULATION; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIPOSOMAL GENE DELIVERY SYSTEM; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; REPORTER GENE; STRUCTURE ACTIVITY RELATION; TUMOR; TUMOR CELL; TUMOR CELL CULTURE; TUMOR XENOGRAFT;

ANIMALS; BASE SEQUENCE; BETA-GALACTOSIDASE; CELL LINE, TUMOR; FEMALE; GENE KNOCKDOWN TECHNIQUES; GENES, REPORTER; GENETIC VECTORS; LIPOSOMES; MICE; MICE, SCID; MOLECULAR SEQUENCE DATA; MONITORING, PHYSIOLOGIC; NANOPARTICLES; NEOPLASMS; RNA, SMALL INTERFERING; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 79953002512     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.2546011     Document Type: Article

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