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Volumn 151, Issue 4, 2011, Pages 671-681

A randomized trial of brimonidine versus timolol in preserving visual function: Results from the low-pressure glaucoma treatment study

Author keywords

[No Author keywords available]

Indexed keywords

BRIMONIDINE; TIMOLOL MALEATE;

EID: 79952984499     PISSN: 00029394     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajo.2010.09.026     Document Type: Article
Times cited : (322)

References (59)
  • 2
    • 2442643730 scopus 로고    scopus 로고
    • Primary open-angle glaucoma
    • DOI 10.1016/S0140-6736(04)16257-0, PII S0140673604162570
    • R.N. Weinreb, and P.T. Khaw Primary open-angle glaucoma Lancet 363 9422 2004 1711 1720 (Pubitemid 38670330)
    • (2004) Lancet , vol.363 , Issue.9422 , pp. 1711-1720
    • Weinreb, R.N.1    Tee Khaw, P.2
  • 3
    • 0001471319 scopus 로고    scopus 로고
    • Normal-tension glaucoma
    • nd ed. 1996 Mosby - Year Book, Inc St.Louis 769 797
    • (1996) The Glaucomas , pp. 769-797
    • Werner, E.B.1
  • 4
    • 0026409550 scopus 로고
    • Relationship between intraocular pressure and primary open angle glaucoma among white and black Americans: The Baltimore Eye Survey
    • A. Sommer, J.M. Tielsch, and J. Katz Relationship between intraocular pressure and primary open angle glaucoma among white and black Americans The Baltimore Eye Survey Arch Ophthalmol 109 8 1991 1090 1095
    • (1991) Arch Ophthalmol , vol.109 , Issue.8 , pp. 1090-1095
    • Sommer, A.1    Tielsch, J.M.2    Katz, J.3
  • 5
    • 0026641023 scopus 로고
    • Prevalence of glaucoma: The Beaver Dam Eye Study
    • B.E. Klein, R. Klein, and W.E. Sponsel Prevalence of glaucoma The Beaver Dam Eye Study Ophthalmology 99 10 1992 1499 1504
    • (1992) Ophthalmology , vol.99 , Issue.10 , pp. 1499-1504
    • Klein, B.E.1    Klein, R.2    Sponsel, W.E.3
  • 6
    • 0036822851 scopus 로고    scopus 로고
    • Reduction of intraocular pressure and glaucoma progression: Results from the Early Manifest Glaucoma Trial
    • A. Heijl, M.C. Leske, B. Bengtsson, L. Hyman, B. Bengtsson, and M. Hussein Reduction of intraocular pressure and glaucoma progression: results from the Early Manifest Glaucoma Trial Arch Ophthalmol 120 10 2002 1268 1279 (Pubitemid 36105431)
    • (2002) Archives of Ophthalmology , vol.120 , Issue.10 , pp. 1268-1279
    • Heijl, A.1    Leske, M.C.2    Bengtsson, B.3    Hyman, L.4    Bengtsson, B.5    Hussein, M.6
  • 8
    • 0033808223 scopus 로고    scopus 로고
    • The Advanced Glaucoma Intervention Study (AGIS). 7: The relationship between control of intraocular pressure and visual field deterioration
    • The AGIS Investigators
    • The AGIS Investigators The Advanced Glaucoma Intervention Study (AGIS). 7: The relationship between control of intraocular pressure and visual field deterioration Am J Ophthalmol 130 4 2000 429 440
    • (2000) Am J Ophthalmol , vol.130 , Issue.4 , pp. 429-440
  • 9
    • 0034765810 scopus 로고    scopus 로고
    • Interim clinical outcomes in the collaborative initial glaucoma treatment study comparing initial treatment randomized to medications or surgery
    • DOI 10.1016/S0161-6420(01)00873-9, PII S0161642001008739
    • P.R. Lichter, D.C. Musch, and B.W. Gillespie Interim clinical outcomes in the Collaborative Initial Treatment Study comparing initial treatment randomized to medications or surgery Ophthalmology 108 11 2001 1943 1953 (Pubitemid 33032760)
    • (2001) Ophthalmology , vol.108 , Issue.11 , pp. 1943-1953
    • Lichter, P.R.1    Musch, D.C.2    Gillespie, B.W.3    Guire, K.E.4    Janz, N.K.5    Wren, P.A.6    Mills, M.P.H.7    Richard, P.8
  • 10
    • 0032189334 scopus 로고    scopus 로고
    • The effectiveness of intraocular pressure reduction in the treatment of normal-tension glaucoma
    • Collaborative Normal-tension Study Group
    • Collaborative Normal-tension Study Group The effectiveness of intraocular pressure reduction in the treatment of normal-tension glaucoma Am J Ophthalmol 126 4 1998 498 505
    • (1998) Am J Ophthalmol , vol.126 , Issue.4 , pp. 498-505
  • 11
    • 0032189255 scopus 로고    scopus 로고
    • Comparison of glaucomatous progression between untreated patients with normal-tension glaucoma and patients with therapeutically reduced intraocular pressures
    • Collaborative Normal-tension Study Group
    • Collaborative Normal-tension Study Group Comparison of glaucomatous progression between untreated patients with normal-tension glaucoma and patients with therapeutically reduced intraocular pressures Am J Ophthalmol 126 4 1998 487 497
    • (1998) Am J Ophthalmol , vol.126 , Issue.4 , pp. 487-497
  • 12
    • 65249098513 scopus 로고    scopus 로고
    • Experimental and clinical evidence for brimonidine as an optic nerve and retinal neuroprotective agent: An evidence-based review
    • M. Saylor, L.K. McLoon, A.R. Harrison, and M.S. Lee Experimental and clinical evidence for brimonidine as an optic nerve and retinal neuroprotective agent: An evidence-based review Arch Ophthalmol 127 4 2009 402 406
    • (2009) Arch Ophthalmol , vol.127 , Issue.4 , pp. 402-406
    • Saylor, M.1    McLoon, L.K.2    Harrison, A.R.3    Lee, M.S.4
  • 13
    • 0032901575 scopus 로고    scopus 로고
    • Brimonidine tartrate 0.2% Twice daily vs timolol 0.5% Twice daily: 1- year results in glaucoma patients
    • DOI 10.1016/S0002-9394(98)00286-4, PII S0002939498002864
    • L.J. Katz Brimonidine Study Group Brimonidine tartrate 0.2% twice daily vs timolol 0.5% twice daily: 1-year results in glaucoma patients Am J Ophthalmol 127 1 1999 20 26 (Pubitemid 29036611)
    • (1999) American Journal of Ophthalmology , vol.127 , Issue.1 , pp. 20-26
    • Katz, L.J.1
  • 14
    • 0033965538 scopus 로고    scopus 로고
    • Ongoing clinical assessment of the safety profile and efficacy of brimonidine compared with timolol: Year-three results
    • DOI 10.1016/S0149-2918(00)87981-3
    • S. Melamed, R. David Brimonidine Study Group II Ongoing clinical assessment of the safety profile and efficacy of brimonidine compared with timolol: year-three results Clin Ther 22 1 2000 103 111 (Pubitemid 30091427)
    • (2000) Clinical Therapeutics , vol.22 , Issue.1 , pp. 103-111
    • Melamed, S.1    David, R.2
  • 15
    • 14644435009 scopus 로고    scopus 로고
    • The Low-pressure Glaucoma Treatment Study (LoGTS): Study design and baseline characteristics of enrolled patients
    • DOI 10.1016/j.ophtha.2004.10.034
    • T. Krupin, J.M. Liebmann, and D.S. Greenfield The Low-pressure Glaucoma Treatment Study (LoGTS): study design and baseline characteristics of enrolled patients Ophthalmology 112 3 2005 376 385 (Pubitemid 40312487)
    • (2005) Ophthalmology , vol.112 , Issue.3 , pp. 376-385
    • Krupin, T.1    Liebmann, J.M.2    Greenfield, D.S.3    Rosenberg, L.F.4    Ritch, R.5    Yang, J.W.6
  • 16
    • 0031793877 scopus 로고    scopus 로고
    • Twelve-month results of an ongoing randomized trial comparing brimonidine tartrate 0.2% and timolol 0.5% given twice daily in patients with glaucoma or ocular hypertension
    • Brimonidine Study Group 2 R.P.
    • R.P. LeBlanc Brimonidine Study Group 2 Twelve-month results of an ongoing randomized trial comparing brimonidine tartrate 0.2% and timolol 0.5% given twice daily in patients with glaucoma or ocular hypertension Ophthalmology 105 10 1998 1960 1967
    • (1998) Ophthalmology , vol.105 , Issue.10 , pp. 1960-1967
    • LeBlanc, R.P.1
  • 17
    • 0025911875 scopus 로고
    • Regression analysis of visual field progression in low tension glaucoma
    • B.N. Noureddin, D. Poinoosawmy, F.W. Fietzke, and R.A. Hitchings Regression analysis of visual field progression in low tension glaucoma Br J Ophthalmol 75 8 1991 493 495
    • (1991) Br J Ophthalmol , vol.75 , Issue.8 , pp. 493-495
    • Noureddin, B.N.1    Poinoosawmy, D.2    Fietzke, F.W.3    Hitchings, R.A.4
  • 18
    • 0032822539 scopus 로고    scopus 로고
    • Methodological variations in estimating apparent progressive visual field loss in clinical trials of glaucoma treatment
    • J. Katz, N. Congdon, and D.S. Friedman Methodological variations in estimating apparent progressive visual field loss in clinical trials of glaucoma treatment Arch Ophthalmol 117 9 1999 1137 1142 (Pubitemid 29428821)
    • (1999) Archives of Ophthalmology , vol.117 , Issue.9 , pp. 1137-1142
    • Katz, J.1    Congdon, N.2    Friedman, D.S.3
  • 20
    • 0033498278 scopus 로고    scopus 로고
    • Early Manifest Glaucoma Trial: Design and baseline data
    • M.C. Leske, A. Heijl, L. Hyman, B. Bengtsson Early Manifest Glaucoma Trial Group Early Manifest Glaucoma Trial: design and baseline data Ophthalmology 106 11 1999 2144 2153 (Pubitemid 30194238)
    • (1999) Ophthalmology , vol.106 , Issue.11 , pp. 2144-2153
    • Leske, M.C.1    Heijl, A.2    Hyman, L.3    Bengtsson, B.4
  • 21
    • 0036241335 scopus 로고    scopus 로고
    • Examination of different pointwise linear regression methods for determining visual field progression
    • S.K. Gardiner, and D.P. Crabb Examination of different pointwise linear regression methods for determining visual field progression Invest Ophthalmol Vis Sci 43 5 2002 1400 1407 (Pubitemid 34462637)
    • (2002) Investigative Ophthalmology and Visual Science , vol.43 , Issue.5 , pp. 1400-1407
    • Gardiner, S.K.1    Crabb, D.P.2
  • 22
    • 1142297498 scopus 로고    scopus 로고
    • Reducing noise in suspected glaucomatous visual fields by using a new spatial filter
    • DOI 10.1016/S0042-6989(03)00474-7
    • S.K. Gardiner, D.P. Crabb, F.W. Fietzke, and R.A. Hitchings Reducing noise in suspected glaucomatous visual fields by using a new spatial filter Vision Res 44 8 2004 839 848 (Pubitemid 38210280)
    • (2004) Vision Research , vol.44 , Issue.8 , pp. 839-848
    • Gardiner, S.K.1    Crabb, D.P.2    Fitzke, F.W.3    Hitchings, R.A.4
  • 23
    • 0017360990 scopus 로고
    • The measurement of observer agreement for categorical data
    • J.R. Landis, and G.G. Koch The measurement of observer agreement for categorical data Biometrics 33 1 1977 159 174 (Pubitemid 8054849)
    • (1977) Biometrics , vol.33 , Issue.1 , pp. 159-174
    • Landis, J.R.1    Koch, G.G.2
  • 24
    • 0030877607 scopus 로고    scopus 로고
    • A 1-year study of brimonidine twice daily in glaucoma and ocular hypertension
    • J.S. Schuman, B. Horwitz, and N.T. Choplin A 1-year study of brimonidine twice daily in glaucoma and ocular hypertension Arch Ophthalmol 115 7 1997 847 852
    • (1997) Arch Ophthalmol , vol.115 , Issue.7 , pp. 847-852
    • Schuman, J.S.1    Horwitz, B.2    Choplin, N.T.3
  • 26
    • 33746754282 scopus 로고    scopus 로고
    • Optic disc and visual field progression in ocular hypertensive subjects: Detection rates, specificity, and agreement
    • DOI 10.1167/iovs.05-1584
    • N.G. Strouthidis, A. Scott, N.M. Peter, and D.F. Garway-Heath Optic disc and visual field progression in ocular hypertensive subjects: detection rates, specificity, and agreement Invest Ophthalmol Vis Sci 47 7 2006 2904 2910 (Pubitemid 351639765)
    • (2006) Investigative Ophthalmology and Visual Science , vol.47 , Issue.7 , pp. 2904-2910
    • Strouthidis, N.G.1    Scott, A.2    Peter, N.M.3    Garway-Heath, D.F.4
  • 27
    • 0037251618 scopus 로고    scopus 로고
    • Factors for glaucoma progression and the effect of treatment: The early manifest glaucoma trial
    • M.C. Leske, A. Heijl, M. Hussein, B. Bengtsson, L. Hyman, and E. Komaroff Factors for glaucoma progression and the effect of treatment: the Early Manifest Glaucoma Trial Arch Ophthalmol 121 1 2003 48 56 (Pubitemid 36401765)
    • (2003) Archives of Ophthalmology , vol.121 , Issue.1 , pp. 48-56
    • Leske, M.C.1    Heijl, A.2    Hussein, M.3    Bengtsson, B.4    Hyman, L.5    Komaroff, E.6
  • 28
    • 70549112634 scopus 로고    scopus 로고
    • Natural history of open-angle glaucoma
    • A. Heijl, B. Bengtsson, L. Hyman, and M.C. Leske Natural history of open-angle glaucoma Ophthalmology 116 12 2009 2271 2276
    • (2009) Ophthalmology , vol.116 , Issue.12 , pp. 2271-2276
    • Heijl, A.1    Bengtsson, B.2    Hyman, L.3    Leske, M.C.4
  • 29
    • 0021961081 scopus 로고
    • Effects of timolol, epinephrine, and acetazolamide on aqueous flow during sleep
    • J.E. Topper, and R.F. Brubaker Effects of timolol, epinephrine, and acetazolamide on aqueous flow during sleep Invest Ophthalmol Vis Sci 26 10 1985 1315 1319 (Pubitemid 15241053)
    • (1985) Investigative Ophthalmology and Visual Science , vol.26 , Issue.10 , pp. 1315-1319
    • Topper, J.E.1    Brubaker, R.F.2
  • 30
    • 0028784773 scopus 로고
    • Effects of brimonidine on aqueous humor dynamics in human eyes
    • C.B. Toris, M.L. Gleason, C.B. Camras, and M.E. Yablonski Effects of brimonidine on aqueous humor dynamics in human eyes Arch Ophthalmol 113 12 1995 1514 1517
    • (1995) Arch Ophthalmol , vol.113 , Issue.12 , pp. 1514-1517
    • Toris, C.B.1    Gleason, M.L.2    Camras, C.B.3    Yablonski, M.E.4
  • 32
    • 0028940089 scopus 로고
    • Hypertension, perfusion pressure, and primary open-angle glaucoma: A population-based assessment
    • J.M. Tielsch, J. Katz, A. Sommer, H.A. Quigley, and J.C. Javitt Hypertension, perfusion pressure, and primary open-angle glaucoma A population-based assessment Arch Ophthalmol 113 2 1995 216 221
    • (1995) Arch Ophthalmol , vol.113 , Issue.2 , pp. 216-221
    • Tielsch, J.M.1    Katz, J.2    Sommer, A.3    Quigley, H.A.4    Javitt, J.C.5
  • 33
    • 0033761608 scopus 로고    scopus 로고
    • Vascular risk factors for primary open angle glaucoma: The Egna-Neumarkt Study
    • L. Bonomi, G. Marchini, M. Marraffa, P. Bernardi, R. Morbio, and A. Varotto Vascular risk factors for primary open angle glaucoma: the Egna-Neumarkt Study Ophthalmology 107 7 2000 1287 1293
    • (2000) Ophthalmology , vol.107 , Issue.7 , pp. 1287-1293
    • Bonomi, L.1    Marchini, G.2    Marraffa, M.3    Bernardi, P.4    Morbio, R.5    Varotto, A.6
  • 34
    • 0035208448 scopus 로고    scopus 로고
    • The prevalence of glaucoma in a population-based study of Hispanic subjects: Proyecto VER
    • H.A. Quigley, S.K. West, J. Rodriguez, B. Munoz, R. Klein, and R. Snyder The prevalence of glaucoma in a population-based study of Hispanic subjects: Proyecto VER Arch Ophthalmol 119 12 2001 1819 1826 (Pubitemid 33139614)
    • (2001) Archives of Ophthalmology , vol.119 , Issue.12 , pp. 1819-1826
    • Quigley, H.A.1    West, S.K.2    Rodriguez, J.3    Munoz, B.4    Klein, R.5    Snyder, R.6
  • 35
    • 34848853772 scopus 로고    scopus 로고
    • Predictors of Long-term Progression in the Early Manifest Glaucoma Trial
    • DOI 10.1016/j.ophtha.2007.03.016, PII S0161642007002412
    • M.C. Leske, A. Heijl, L. Hyman, B. Bengtsson, L. Dong, and Z. Yang Predictors of long-term progression in the Early Manifest Glaucoma Trial Ophthalmology 114 11 2007 1965 1972 (Pubitemid 350016362)
    • (2007) Ophthalmology , vol.114 , Issue.11 , pp. 1965-1972
    • Leske, M.C.1    Heijl, A.2    Hyman, L.3    Bengtsson, B.4    Dong, L.5    Yang, Z.6
  • 36
    • 0028814882 scopus 로고
    • The cardiovascular, pulmonary, and ocular hypotensive effects of 0.2% brimonidine
    • J.R. Nordlund, L.R. Pasquale, and A.L. Robin The cardiovascular, pulmonary, and ocular hypotensive effects of 0.2% brimonidine Arch Ophthalmol 113 1 1995 77 83
    • (1995) Arch Ophthalmol , vol.113 , Issue.1 , pp. 77-83
    • Nordlund, J.R.1    Pasquale, L.R.2    Robin, A.L.3
  • 37
    • 0032877851 scopus 로고    scopus 로고
    • Beta-blocker eyedrops and nocturnal arterial hypotension
    • DOI 10.1016/S0002-9394(99)00160-9, PII S0002939499001609
    • S.S. Hayreh, P. Podhajsky, and M.B. Zimmerman Beta-blocker eyedrops and nocturnal arterial hypotension Am J Ophthalmol 128 3 1999 301 309 (Pubitemid 29413226)
    • (1999) American Journal of Ophthalmology , vol.128 , Issue.3 , pp. 301-309
    • Hayreh, S.S.1    Podhajsky, P.2    Zimmerman, M.B.3
  • 40
    • 0028097839 scopus 로고
    • A controlled trial of riluzole in amyotrophic lateral sclerosis
    • DOI 10.1056/NEJM199403033300901
    • G. Bensimon, L. Lacomblez, and V. Meininger A controlled trial of riluzole in amyotrophic lateral sclerosis ALS/Riluzole Study Group N Engl J Med 330 9 1994 585 591 (Pubitemid 24065791)
    • (1994) New England Journal of Medicine , vol.330 , Issue.9 , pp. 585-591
    • Bensimon, G.1    Lacomblez, L.2    Meininger, V.3
  • 41
    • 25144518193 scopus 로고    scopus 로고
    • Why have neuroprotectants failed? Lessons learned from stroke trials
    • DOI 10.1007/s00415-005-0933-6
    • K.W. Muir, and P.A. Teal Why have neuro-protectants failed?: lessons learned from stroke trials J Neurol 252 9 2005 1011 1020 (Pubitemid 41355828)
    • (2005) Journal of Neurology , vol.252 , Issue.9 , pp. 1011-1020
    • Muir, K.W.1    Teal, P.A.2
  • 42
    • 67650432133 scopus 로고    scopus 로고
    • Neuroprotection: Extrapolating from neurologic diseases to the eye
    • H.V. Danesh-Meyer, and L.A. Levin Neuroprotection: Extrapolating from neurologic diseases to the eye Am J Ophthalmol 148 2 2009 186 191
    • (2009) Am J Ophthalmol , vol.148 , Issue.2 , pp. 186-191
    • Danesh-Meyer, H.V.1    Levin, L.A.2
  • 43
    • 0032725983 scopus 로고    scopus 로고
    • Is neuroprotection a viable therapy for glaucoma?
    • R.N. Weinreb, and L.A. Levin Is neuroprotection a viable therapy for glaucoma? Arch Ophthalmol 117 11 1999 1540 1544 (Pubitemid 29536483)
    • (1999) Archives of Ophthalmology , vol.117 , Issue.11 , pp. 1540-1544
    • Weinreb, R.N.1    Levin, L.A.2
  • 44
    • 0036201295 scopus 로고    scopus 로고
    • Current understanding of neuroprotection in glaucoma
    • DOI 10.1097/00055735-200204000-00002
    • F.B. Wein, and L.A. Levin Current understanding of neuroprotection in glaucoma Curr Opin Ophthalmol 13 2 2002 61 67 (Pubitemid 34261263)
    • (2002) Current Opinion in Ophthalmology , vol.13 , Issue.2 , pp. 61-67
    • Wein, F.B.1    Levin, L.A.2
  • 47
    • 0027248053 scopus 로고
    • 2-adrenoreceptor agonist dexmedetomidine in a focal model of cerebral ischemia
    • C. Maier, G.K. Steinberg, G.H. Sun, G.T. Zhi, and M. Maze Neuroprotection by the alpha 2-adrenoreceptor agonist dexmedetomidine in a focal model of cerebral ischemia Anesthesiology 79 2 1993 306 312 (Pubitemid 23224843)
    • (1993) Anesthesiology , vol.79 , Issue.2 , pp. 306-312
    • Maier, C.1    Steinberg, G.K.2    Guo Hua Sun3    Guo Tian Zhi4    Maze, M.5
  • 48
    • 0032904676 scopus 로고    scopus 로고
    • From the lab to the clinic: Activation of an alpha-2 agonist pathway is neuroprotective in models of retinal and optic nerve injury
    • L.A. Wheeler, R. Lai, and E. WoldeMussie From the lab to the clinic: activation of an alpha-2 agonist pathway is neuroprotective in models of retinal and optic nerve injury Eur J Ophthalmol 9 suppl 1 1999 S17 S21
    • (1999) Eur J Ophthalmol , vol.9 , Issue.SUPPL. 1
    • Wheeler, L.A.1    Lai, R.2    Woldemussie, E.3
  • 49
    • 35948964778 scopus 로고    scopus 로고
    • Localization of alpha 2 receptors in ocular tissues
    • DOI 10.1017/S0952523807070605, PII S0952523807070605
    • E. WoldeMussie, M. Wijono, and D. Pow Localization of alpha 2 receptors in ocular tissues Vis Neurosci 24 5 2007 745 756 (Pubitemid 350073511)
    • (2007) Visual Neuroscience , vol.24 , Issue.5 , pp. 745-756
    • Woldemussie, E.1    Wijono, M.2    Pow, D.3
  • 50
    • 0026686801 scopus 로고
    • Localization of alpha-2 adrenergic receptors in the human eye
    • T. Matsuo, and M.S. Cynader Localization of alpha-2 adrenergic receptors in the human eye Ophthalmic Res 24 4 1992 213 219
    • (1992) Ophthalmic Res , vol.24 , Issue.4 , pp. 213-219
    • Matsuo, T.1    Cynader, M.S.2
  • 51
    • 0032622411 scopus 로고    scopus 로고
    • α2-Adrenoreceptor agonists are neuroprotective in a rat model of optic nerve degeneration
    • E. Yoles, L.A. Wheeler, and M. Schwartz Alpha2-adrenoreceptor agonists are neuroprotective in a rat model of optic nerve degeneration Invest Ophthalmol Vis Sci 40 1 1999 65 73 (Pubitemid 29029573)
    • (1999) Investigative Ophthalmology and Visual Science , vol.40 , Issue.1 , pp. 65-73
    • Yoles, E.1    Wheeler, L.A.2    Schwartz, M.3
  • 52
    • 0034754201 scopus 로고    scopus 로고
    • Neuroprotection of retinal ganglion cells by brimonidine in rats with laser-induced chronic ocular hypertension
    • E. WoldeMussie, G. Ruiz, M. Wijono, and L.A. Wheeler Neuroprotection of retinal ganglion cells by brimonidine in rats with laser-induced chronic ocular hypertension Invest Ophthalmol Vis Sci 42 11 2001 2849 2855 (Pubitemid 33035282)
    • (2001) Investigative Ophthalmology and Visual Science , vol.42 , Issue.12 , pp. 2849-2855
    • WoldeMussie, E.1    Ruiz, G.2    Wijono, M.3    Wheeler, L.A.4
  • 53
    • 42749091665 scopus 로고    scopus 로고
    • Retinal ganglion cell neuroprotection in a rat model of glaucoma following brimonidine, latanoprost or combined treatments
    • M. Hernndez, J.H. Urcola, and E. Vecino Retinal ganglion cell neuroprotection in a rat model of glaucoma following brimonidine, latanoprost or combined treatments Exp Eye Res 86 5 2008 798 806
    • (2008) Exp Eye Res , vol.86 , Issue.5 , pp. 798-806
    • Hernndez, M.1    Urcola, J.H.2    Vecino, E.3
  • 54
    • 0036272780 scopus 로고    scopus 로고
    • Up-regulation of brain-derived neurotrophic factor expression by brimonidine in rat retinal ganglion cells
    • H. Gao, X. Qiao, L.B. Cantor, and D. WuDunn Up-regulation of brain-derived neurotrophic factor expression by brimonidine in rat retinal ganglion cells Arch Ophthalmol 120 6 2002 797 803 (Pubitemid 34620360)
    • (2002) Archives of Ophthalmology , vol.120 , Issue.6 , pp. 797-803
    • Gao, H.1    Qiao, X.2    Cantor, L.B.3    WuDunn, D.4
  • 55
    • 0036489583 scopus 로고    scopus 로고
    • Alpha-2 adrenoceptor agonist protects retinal function after acute retinal ischemic injury in the rat
    • DOI 017.S0952523802191152
    • R.K. Lai, T. Chun, D. Hasson, S. Lee, F. Mehrbod, and L. Wheeler Alpha-2 adrenoceptor agonist protects retinal function after acute retinal ischemic injury in the rat Vis Neurosci 19 2 2002 175 185 (Pubitemid 35230993)
    • (2002) Visual Neuroscience , vol.19 , Issue.2 , pp. 175-185
    • Lai, R.K.1    Chun, T.2    Hasson, D.3    Lee, S.4    Mehrbod, F.5    Wheeler, L.6
  • 56
    • 53449088505 scopus 로고    scopus 로고
    • Alpha2 adrenergic modulation of NMDA receptor function as a major mechanism of RGC protection in experimental glaucoma and retinal excitotoxicity
    • C.-J. Dong, Y. Guo, P. Agey, L. Wheeler, and W.A. Hare Alpha2 adrenergic modulation of NMDA receptor function as a major mechanism of RGC protection in experimental glaucoma and retinal excitotoxicity Invest Ophthalmol Vis Sci 49 10 2008 4515 4522
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , Issue.10 , pp. 4515-4522
    • Dong, C.-J.1    Guo, Y.2    Agey, P.3    Wheeler, L.4    Hare, W.A.5
  • 57
    • 0029752042 scopus 로고    scopus 로고
    • Preclinical evaluation of brimonidine
    • J. Burke, and M. Schwartz Preclinical evaluation of brimonidine Surv Ophthalmol 41 Suppl 1 1996 S9 S18
    • (1996) Surv Ophthalmol , vol.41 , Issue.SUPPL. 1
    • Burke, J.1    Schwartz, M.2
  • 58
    • 0842268223 scopus 로고    scopus 로고
    • Role of alpha-2 agonists in neuroprotection
    • L. Wheeler, E. WoldeMussie, and R. Lai Role of alpha-2 agonists in neuroprotection Surv Ophthalmol 48 Suppl 1 2003 547 551
    • (2003) Surv Ophthalmol , vol.48 , Issue.SUPPL. 1 , pp. 547-551
    • Wheeler, L.1    Woldemussie, E.2    Lai, R.3
  • 59
    • 0035082121 scopus 로고    scopus 로고
    • Vitreous concentration of topically applied brimonidine tartrate 0.2%
    • DOI 10.1016/S0161-6420(00)00654-0
    • A.R. Kent, J.D. Nussdorf, R. David, F. Tyson, D. Small, and D. Fellows Vitreous concentration of topically applied brimonidine tartrate 0.2% Ophthalmology 108 4 2001 784 787 (Pubitemid 32238477)
    • (2001) Ophthalmology , vol.108 , Issue.4 , pp. 784-787
    • Kent, A.R.1    Nussdorf, J.D.2    David, R.3    Tyson, F.4    Small, D.5    Fellows, D.6


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