메뉴 건너뛰기




Volumn 9, Issue SUPPL. 1, 1999, Pages

From the lab to the clinic: Activation of an alpha-2 agonist pathway is neuroprotective in models of retinal and optic-nerve injury

Author keywords

Acute retinal ischemic injury; Alpha 2 adrenoreceptor agonist; Brimonidine; Neuroprotection; Optic nerve injury; Rat crush injury model; TUNEL staining

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BRIMONIDINE;

EID: 0032904676     PISSN: 11206721     EISSN: None     Source Type: Journal    
DOI: 10.1177/112067219900901s09     Document Type: Article
Times cited : (94)

References (17)
  • 1
    • 0028907952 scopus 로고
    • Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis
    • Quigley HA, Nickells RW, Kerrigan LA, et al. Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis. Invest Ophthalmol Vis Sci 1995; 36: 774-86.
    • (1995) Invest Ophthalmol Vis Sci , vol.36 , pp. 774-786
    • Quigley, H.A.1    Nickells, R.W.2    Kerrigan, L.A.3
  • 2
    • 0030925834 scopus 로고    scopus 로고
    • Apoptosis in retinal ganglion cell decrease in human glaucomatous eyes
    • Okisaka S, Murakami A, Mizukawa A, Ito J. Apoptosis in retinal ganglion cell decrease in human glaucomatous eyes. Jpn J Ophthalmol 1997; 41: 84-8.
    • (1997) Jpn J Ophthalmol , vol.41 , pp. 84-88
    • Okisaka, S.1    Murakami, A.2    Mizukawa, A.3    Ito, J.4
  • 4
    • 0029908754 scopus 로고    scopus 로고
    • Retinal ganglior cell death in glaucoma: The how, the why and the maybe
    • Nickells RW. Retinal ganglior cell death in glaucoma: The how, the why and the maybe. J Glaucoma 1996; 5: 345-56.
    • (1996) J Glaucoma , vol.5 , pp. 345-356
    • Nickells, R.W.1
  • 5
    • 0029778159 scopus 로고    scopus 로고
    • Chronic low-dose glutamate is toxic to retinal ganglion cells
    • Vorwerk CK, Lipton SA, Zurakowski D, et al. Chronic low-dose glutamate is toxic to retinal ganglion cells. Invest Ophthalmol Vis Sci 1996; 37: 1618-24.
    • (1996) Invest Ophthalmol Vis Sci , vol.37 , pp. 1618-1624
    • Vorwerk, C.K.1    Lipton, S.A.2    Zurakowski, D.3
  • 6
    • 0025665165 scopus 로고
    • Graded crush of the rat optic nerve as a brain injury model: Combining electrophysiological and behavioral outcome
    • Duvdevani R, Rosner M, Belkin M, Sautter J, Sabel BA, Schwartz M. Graded crush of the rat optic nerve as a brain injury model: combining electrophysiological and behavioral outcome. Restor Neurol Neurosci 1990; 2: 31-8.
    • (1990) Restor Neurol Neurosci , vol.2 , pp. 31-38
    • Duvdevani, R.1    Rosner, M.2    Belkin, M.3    Sautter, J.4    Sabel, B.A.5    Schwartz, M.6
  • 7
    • 0031789649 scopus 로고    scopus 로고
    • Elevation of intraocular glutamate levels in rats with partial lesion of the optic nerve
    • Yoles E, Schwartz M. Elevation of intraocular glutamate levels in rats with partial lesion of the optic nerve. Arch Ophthalmol 1998; 116: 906-10.
    • (1998) Arch Ophthalmol , vol.116 , pp. 906-910
    • Yoles, E.1    Schwartz, M.2
  • 8
    • 0029069797 scopus 로고
    • Programmed cell death of retinal ganglion cells during experimental glaucoma
    • Garcia-Valenzuela E, Shareef S, Walsh J, Sharma SC. Programmed cell death of retinal ganglion cells during experimental glaucoma. Exp Eye Res 1995; 61: 33-44
    • (1995) Exp Eye Res , vol.61 , pp. 33-44
    • Garcia-Valenzuela, E.1    Shareef, S.2    Walsh, J.3    Sharma, S.C.4
  • 9
    • 0032622411 scopus 로고    scopus 로고
    • Alpha-2-adrenoreceptor agonists are neuroprolective in a rat model of optic nerve degeneration
    • Yoles E, Wheeler LA, Schwartz M. Alpha-2-adrenoreceptor agonists are neuroprolective in a rat model of optic nerve degeneration. Invest Ophthalmol Vis Sci 1999; 40: 65-73.
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , pp. 65-73
    • Yoles, E.1    Wheeler, L.A.2    Schwartz, M.3
  • 10
    • 0032033868 scopus 로고    scopus 로고
    • Growth factors and gangliosides as neuroprotective agents in excitotoxicity and ishemia
    • Hicks D, Heidinger V, Mohand-Said S, Sahel J, Dreyfus H. Growth factors and gangliosides as neuroprotective agents in excitotoxicity and ishemia. Gen Pharmacol 1998; 30: 265-73.
    • (1998) Gen Pharmacol , vol.30 , pp. 265-273
    • Hicks, D.1    Heidinger, V.2    Mohand-Said, S.3    Sahel, J.4    Dreyfus, H.5
  • 11
    • 0023257035 scopus 로고
    • Fibroblast growth factors promote the survival or adult rat retinal cells after transection of the optic nerve
    • Sievers J, Hausmann B, Unsicker K, Berry M. Fibroblast growth factors promote the survival or adult rat retinal cells after transection of the optic nerve. Neurosci Lett 1987; 76: 157-62.
    • (1987) Neurosci Lett , vol.76 , pp. 157-162
    • Sievers, J.1    Hausmann, B.2    Unsicker, K.3    Berry, M.4
  • 12
    • 0029979673 scopus 로고    scopus 로고
    • Effects of axotomy and intraocular administration of NT-4, NT-3, and brain-derived neurotrophic factor on the survival of adult rat retinal ganglion cells
    • Peinado-Ramon P, Salvador M, Villegas-Perez MP. Vidal-Sanz M. Effects of axotomy and intraocular administration of NT-4, NT-3, and brain-derived neurotrophic factor on the survival of adult rat retinal ganglion cells. Invest Ophthalmol Vis Sci 1996; 37: 489-500.
    • (1996) Invest Ophthalmol Vis Sci , vol.37 , pp. 489-500
    • Peinado-Ramon, P.1    Salvador, M.2    Villegas-Perez, M.P.3    Vidal-Sanz, M.4
  • 14
    • 0029788373 scopus 로고    scopus 로고
    • Alpha 2-adrenergic agonists induce basic fibroblast growth factor expression in photoreceptors in vivo and ameliorate light damage
    • Wen R, Cheng T, Li Y, Cao W, Steinberg RH. Alpha 2-adrenergic agonists induce basic fibroblast growth factor expression in photoreceptors in vivo and ameliorate light damage. J Neurosci 1996; 16: 5986-92.
    • (1996) J Neurosci , vol.16 , pp. 5986-5992
    • Wen, R.1    Cheng, T.2    Li, Y.3    Cao, W.4    Steinberg, R.H.5
  • 15
    • 0031596327 scopus 로고    scopus 로고
    • Alpha-2-adrenergic agonists selectively activate extracellular signal-regulated kinases in Müller cells in vivo
    • Peng M, Yiwen L, Zhijun L, Liu C, Lattes A, Wen R. Alpha-2-adrenergic agonists selectively activate extracellular signal-regulated kinases in Müller cells in vivo. Invest Ophthalmol Vis Sci 1998; 39: 1721-6.
    • (1998) Invest Ophthalmol Vis Sci , vol.39 , pp. 1721-1726
    • Peng, M.1    Yiwen, L.2    Zhijun, L.3    Liu, C.4    Lattes, A.5    Wen, R.6
  • 16
    • 0001895165 scopus 로고    scopus 로고
    • Functional protection of rat retina ischemic injury by brimonidine
    • Hasson D, Lai RK, Chun T, Wheeler LA. Functional protection of rat retina ischemic injury by brimonidine. Soc Neurosci 1997; 23: 72-4.
    • (1997) Soc Neurosci , vol.23 , pp. 72-74
    • Hasson, D.1    Lai, R.K.2    Chun, T.3    Wheeler, L.A.4
  • 17
    • 0031918223 scopus 로고    scopus 로고
    • Bcl-2 family: Regulators of cell death
    • Chao DT, Korsmeyer SJ. Bcl-2 family: regulators of cell death. Annu Rev Immunol 1998; 16: 395-419.
    • (1998) Annu Rev Immunol , vol.16 , pp. 395-419
    • Chao, D.T.1    Korsmeyer, S.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.