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Volumn 38, Issue 2, 2011, Pages 236-242

Molecular profiling of melanoma and the evolution of patient-specific therapy

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYLTRYPTOPHAN; ALBINTERFERON ALPHA2B; B RAF KINASE; CARBOPLATIN; DACARBAZINE; DACLIZUMAB; DENILEUKIN DIFTITOX; GAMMA SECRETASE INHIBITOR; IMATINIB; INDOLEAMINE 2,3 DIOXYGENASE INHIBITOR; INTERLEUKIN 2; IPILIMUMAB; LAPATINIB; MELANOMA ANTIGEN 3; MELANOMA VACCINE; MONOCLONAL ANTIBODY; NILOTINIB; PACLITAXEL; PD 1 MONOCLONAL ANTIBODY; PLX 4032; PROTEIN FARNESYLTRANSFERASE INHIBITOR; SORAFENIB; STAT3 PROTEIN; STEM CELL FACTOR RECEPTOR; TEMOZOLOMIDE; TUMOR MARKER; UNCLASSIFIED DRUG;

EID: 79952980159     PISSN: 00937754     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.seminoncol.2011.01.004     Document Type: Article
Times cited : (30)

References (65)
  • 2
    • 53949108399 scopus 로고    scopus 로고
    • Phase III trial comparing concurrent biochemotherapy with cisplatin, vinblastine, dacarbazine, interleukin-2, and interferon alfa-2b with cisplatin, vinblastine, and dacarbazine alone in patients with metastatic malignant melanoma (E3695): A trial coordinated by the Eastern Cooperative Oncology Group
    • M.B. Atkins, J. Hsu, and S. Lee Phase III trial comparing concurrent biochemotherapy with cisplatin, vinblastine, dacarbazine, interleukin-2, and interferon alfa-2b with cisplatin, vinblastine, and dacarbazine alone in patients with metastatic malignant melanoma (E3695): a trial coordinated by the Eastern Cooperative Oncology Group J Clin Oncol 26 2008 5748 5754
    • (2008) J Clin Oncol , vol.26 , pp. 5748-5754
    • Atkins, M.B.1    Hsu, J.2    Lee, S.3
  • 4
    • 0035964396 scopus 로고    scopus 로고
    • A monoclonal cytolytic T-lymphocyte response observed in a melanoma patient vaccinated with a tumor-specific antigenic peptide encoded by gene MAGE-3
    • P.G. Coulie, V. Karanikas, and D. Colau A monoclonal cytolytic T-lymphocyte response observed in a melanoma patient vaccinated with a tumor-specific antigenic peptide encoded by gene MAGE-3 Proc Natl Acad Sci U S A 21 2001 21
    • (2001) Proc Natl Acad Sci U S A , vol.21 , pp. 21
    • Coulie, P.G.1    Karanikas, V.2    Colau, D.3
  • 7
    • 77958012775 scopus 로고    scopus 로고
    • Gene signature in melanoma associated with clinical activity: A potential clue to unlock cancer immunotherapy
    • T.F. Gajewski, J. Louahed, and V.G. Brichard Gene signature in melanoma associated with clinical activity: a potential clue to unlock cancer immunotherapy Cancer J 16 2010 399 403
    • (2010) Cancer J , vol.16 , pp. 399-403
    • Gajewski, T.F.1    Louahed, J.2    Brichard, V.G.3
  • 8
    • 66149156276 scopus 로고    scopus 로고
    • Chemokine expression in melanoma metastases associated with CD8+ T-cell recruitment
    • H. Harlin, Y. Meng, and A.C. Peterson Chemokine expression in melanoma metastases associated with CD8+ T-cell recruitment Cancer Res 69 2009 3077 3085
    • (2009) Cancer Res , vol.69 , pp. 3077-3085
    • Harlin, H.1    Meng, Y.2    Peterson, A.C.3
  • 9
    • 77958006271 scopus 로고    scopus 로고
    • Association of gene expression profile in melanoma and survival to a dendritic cell-based vaccine
    • T.F. Gajewski, Y. Zha, B. Thurner, and G. Schuler Association of gene expression profile in melanoma and survival to a dendritic cell-based vaccine J Clin Oncol 27 15s 2009 9002
    • (2009) J Clin Oncol , vol.27 , Issue.15 S , pp. 9002
    • Gajewski, T.F.1    Zha, Y.2    Thurner, B.3    Schuler, G.4
  • 10
    • 70349417094 scopus 로고    scopus 로고
    • Association of gene expression signature and clinical efficacy of MAGE-A3 antigen-specific cancer immunotherapeutic (ASCI) as adjuvant therapy in resected stage IB/II non-small cell lung cancer (NSCLC)
    • J.F. Vansteenkiste, M. Zielinski, and I.J. Dahabreh Association of gene expression signature and clinical efficacy of MAGE-A3 antigen-specific cancer immunotherapeutic (ASCI) as adjuvant therapy in resected stage IB/II non-small cell lung cancer (NSCLC) J Clin Oncol 26 20 suppl 2008 abstract 7501
    • (2008) J Clin Oncol , vol.26 , Issue.20 SUPPL.
    • Vansteenkiste, J.F.1    Zielinski, M.2    Dahabreh, I.J.3
  • 11
    • 33745632047 scopus 로고    scopus 로고
    • + T cells in a patient with malignant melanoma ascites
    • DOI 10.1007/s00262-005-0118-2
    • H. Harlin, T.V. Kuna, A.C. Peterson, Y. Meng, and T.F. Gajewski Tumor progression despite massive influx of activated CD8(+) T cells in a patient with malignant melanoma ascites Cancer Immunol Immunother 55 2006 1185 1197 (Pubitemid 43992045)
    • (2006) Cancer Immunology, Immunotherapy , vol.55 , Issue.10 , pp. 1185-1197
    • Harlin, H.1    Kuna, T.V.2    Peterson, A.C.3    Meng, Y.4    Gajewski, T.F.5
  • 15
    • 34848819211 scopus 로고    scopus 로고
    • Failure at the effector phase: Immune barriers at the level of the melanoma tumor microenvironment
    • DOI 10.1158/1078-0432.CCR-07-0892
    • T.F. Gajewski Failure at the effector phase: immune barriers at the level of the melanoma tumor microenvironment Clin Cancer Res 13 2007 5256 5261 (Pubitemid 47510348)
    • (2007) Clinical Cancer Research , vol.13 , Issue.18 , pp. 5256-5261
    • Gajewski, T.F.1
  • 17
    • 0038796692 scopus 로고    scopus 로고
    • B7-H1 pathway and its role in the evasion of tumor immunity
    • H. Dong, and L. Chen B7-H1 pathway and its role in the evasion of tumor immunity J Mol Med 81 2003 281 287 (Pubitemid 36718324)
    • (2003) Journal of Molecular Medicine , vol.81 , Issue.5 , pp. 281-287
    • Dong, H.1    Chen, L.2
  • 19
    • 0042389785 scopus 로고    scopus 로고
    • T cell anergy
    • DOI 10.1146/annurev.immunol.21.120601.141110
    • R.H. Schwartz T cell anergy Annu Rev Immunol 21 2003 305 334 (Pubitemid 37174534)
    • (2003) Annual Review of Immunology , vol.21 , pp. 305-334
    • Schwartz, R.H.1
  • 20
    • 47549093234 scopus 로고    scopus 로고
    • Cancer immunotherapy targeting tumour-specific antigens: Towards a new therapy for minimal residual disease
    • DOI 10.1517/14712598.8.7.951
    • V.G. Brichard, and D. Lejeune Cancer immunotherapy targeting tumour-specific antigens: towards a new therapy for minimal residual disease Expert Opin Biol Ther 8 2008 951 968 (Pubitemid 352007006)
    • (2008) Expert Opinion on Biological Therapy , vol.8 , Issue.7 , pp. 951-968
    • Brichard, V.G.1    Lejeune, D.2
  • 21
    • 23644447237 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase in cancer: Targeting pathological immune tolerance with small-molecule inhibitors
    • DOI 10.1517/14728222.9.4.831
    • A.J. Muller, W.P. Malachowski, and G.C. Prendergast Indoleamine 2,3-dioxygenase in cancer: targeting pathological immune tolerance with small-molecule inhibitors Expert Opin Ther Targets 9 2005 831 849 (Pubitemid 41131682)
    • (2005) Expert Opinion on Therapeutic Targets , vol.9 , Issue.4 , pp. 831-849
    • Muller, A.J.1    Malachowski, W.P.2    Prendergast, G.C.3
  • 24
    • 70349561448 scopus 로고    scopus 로고
    • PD-1/PD-L1 interactions inhibit antitumor immune responses in a murine acute myeloid leukemia model
    • L. Zhang, T.F. Gajewski, and J. Kline PD-1/PD-L1 interactions inhibit antitumor immune responses in a murine acute myeloid leukemia model Blood 114 2009 1545 1552
    • (2009) Blood , vol.114 , pp. 1545-1552
    • Zhang, L.1    Gajewski, T.F.2    Kline, J.3
  • 26
    • 33749135271 scopus 로고    scopus 로고
    • + T cell anergy and promotes tumor rejection
    • I.E. Brown, C. Blank, J. Kline, A.K. Kacha, and T.F. Gajewski Homeostatic proliferation as an isolated variable reverses CD8+ T cell anergy and promotes tumor rejection J Immunol 177 2006 4521 4529 (Pubitemid 44469783)
    • (2006) Journal of Immunology , vol.177 , Issue.7 , pp. 4521-4529
    • Brown, I.E.1    Blank, C.2    Kline, J.3    Kacha, A.K.4    Gajewski, T.F.5
  • 27
    • 77951718214 scopus 로고    scopus 로고
    • Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity
    • X. Liu, N. Shin, and H.K. Koblish Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity Blood 115 2010 3520 3530
    • (2010) Blood , vol.115 , pp. 3520-3530
    • Liu, X.1    Shin, N.2    Koblish, H.K.3
  • 28
    • 77955917121 scopus 로고    scopus 로고
    • Safety and antitumor activity of biweekly MDX-1106 (Anti-PD-1, BMS-936558/ONO-4538) in patients with advanced refractory malignancies
    • M. Sznol, J.D. Powderly, and D.C. Smith Safety and antitumor activity of biweekly MDX-1106 (Anti-PD-1, BMS-936558/ONO-4538) in patients with advanced refractory malignancies J Clin Oncol 28 15s 2010 abstract 2506
    • (2010) J Clin Oncol , vol.28 , Issue.15 S
    • Sznol, M.1    Powderly, J.D.2    Smith, D.C.3
  • 30
    • 70350496784 scopus 로고    scopus 로고
    • Clinical use of anti-CD25 antibody daclizumab to enhance immune responses to tumor antigen vaccination by targeting regulatory T cells
    • A.J. Rech, and R.H. Vonderheide Clinical use of anti-CD25 antibody daclizumab to enhance immune responses to tumor antigen vaccination by targeting regulatory T cells Ann N Y Acad Sci 1174 2009 99 106
    • (2009) Ann N y Acad Sci , vol.1174 , pp. 99-106
    • Rech, A.J.1    Vonderheide, R.H.2
  • 31
    • 42649136634 scopus 로고    scopus 로고
    • Transient T cell depletion causes regression of melanoma metastases
    • M.A. Rasku, A.L. Clem, and S. Telang Transient T cell depletion causes regression of melanoma metastases J Transl Med 6 2008 12
    • (2008) J Transl Med , vol.6 , pp. 12
    • Rasku, M.A.1    Clem, A.L.2    Telang, S.3
  • 33
    • 79251522796 scopus 로고    scopus 로고
    • A single center experience with high-dose IL-2 treatment for patients with advanced melanoma and pilot investigation of a novel gene expression signature as a predictor of response
    • R.J. Sullivan, Y. Hoshida, and J. Brunet A single center experience with high-dose IL-2 treatment for patients with advanced melanoma and pilot investigation of a novel gene expression signature as a predictor of response J Clin Oncol 27 15s 2009 abstract 9003
    • (2009) J Clin Oncol , vol.27 , Issue.15 S
    • Sullivan, R.J.1    Hoshida, Y.2    Brunet, J.3
  • 34
    • 77955253357 scopus 로고    scopus 로고
    • Association of baseline and on-study tumor biopsy markers with clinical activity in patients with advanced melanoma treated with ipilimumab
    • O. Hamid, S.D. Chasalow, Z. Tsuchihashi, S. Alaparthy, S. Galbraith, and D. Berman Association of baseline and on-study tumor biopsy markers with clinical activity in patients with advanced melanoma treated with ipilimumab J Clin Oncol 27 15s 2009 abstract 9008
    • (2009) J Clin Oncol , vol.27 , Issue.15 S
    • Hamid, O.1    Chasalow, S.D.2    Tsuchihashi, Z.3    Alaparthy, S.4    Galbraith, S.5    Berman, D.6
  • 37
    • 51049095131 scopus 로고    scopus 로고
    • A phase i trial of the oral, multikinase inhibitor sorafenib in combination with carboplatin and paclitaxel
    • K.T. Flaherty, J. Schiller, and L.M. Schuchter A phase I trial of the oral, multikinase inhibitor sorafenib in combination with carboplatin and paclitaxel Clin Cancer Res 14 2008 4836 4842
    • (2008) Clin Cancer Res , vol.14 , pp. 4836-4842
    • Flaherty, K.T.1    Schiller, J.2    Schuchter, L.M.3
  • 38
    • 77956033802 scopus 로고    scopus 로고
    • Final results of E2603: A double-blind, randomized phase III trial comparing carboplatin (C)/paclitaxel (P) with or without sorafenib (S) in metastatic melanoma
    • K.T. Flaherty, S.J. Lee, and L.M. Schuchter Final results of E2603: A double-blind, randomized phase III trial comparing carboplatin (C)/paclitaxel (P) with or without sorafenib (S) in metastatic melanoma J Clin Oncol 28 15s 2010 abstract 8511
    • (2010) J Clin Oncol , vol.28 , Issue.15 S
    • Flaherty, K.T.1    Lee, S.J.2    Schuchter, L.M.3
  • 39
    • 33947390695 scopus 로고    scopus 로고
    • Phase II study of the farnesyltransferase inhibitor R115777 in advanced melanoma: CALGB 500104
    • T.F. Gajewski, D. Niedzwiecki, and J. Johnson Phase II study of the farnesyltransferase inhibitor R115777 in advanced melanoma: CALGB 500104 J Clin Oncol 24 18s 2006 abstract 8014
    • (2006) J Clin Oncol , vol.24 , Issue.18 S
    • Gajewski, T.F.1    Niedzwiecki, D.2    Johnson, J.3
  • 40
    • 77956030786 scopus 로고    scopus 로고
    • Inhibition of mutated, activated BRAF in metastatic melanoma
    • K.T. Flaherty, I. Puzanov, and K.B. Kim Inhibition of mutated, activated BRAF in metastatic melanoma N Engl J Med 363 2010 809 819
    • (2010) N Engl J Med , vol.363 , pp. 809-819
    • Flaherty, K.T.1    Puzanov, I.2    Kim, K.B.3
  • 41
    • 58149260596 scopus 로고    scopus 로고
    • KIT gene mutations and copy number in melanoma subtypes
    • C. Beadling, E. Jacobson-Dunlop, and F.S. Hodi KIT gene mutations and copy number in melanoma subtypes Clin Cancer Res 14 2008 6821 6828
    • (2008) Clin Cancer Res , vol.14 , pp. 6821-6828
    • Beadling, C.1    Jacobson-Dunlop, E.2    Hodi, F.S.3
  • 42
    • 57449093330 scopus 로고    scopus 로고
    • Analysis of c-KIT expression and KIT gene mutation in human mucosal melanomas
    • I. Satzger, T. Schaefer, and U. Kuettler Analysis of c-KIT expression and KIT gene mutation in human mucosal melanomas Br J Cancer 99 2008 2065 2069
    • (2008) Br J Cancer , vol.99 , pp. 2065-2069
    • Satzger, I.1    Schaefer, T.2    Kuettler, U.3
  • 44
    • 42949128595 scopus 로고    scopus 로고
    • Major response to imatinib mesylate in KIT-mutated melanoma
    • F.S. Hodi, P. Friedlander, and C.L. Corless Major response to imatinib mesylate in KIT-mutated melanoma J Clin Oncol 26 2008 2046 2051
    • (2008) J Clin Oncol , vol.26 , pp. 2046-2051
    • Hodi, F.S.1    Friedlander, P.2    Corless, C.L.3
  • 45
    • 47249099056 scopus 로고    scopus 로고
    • Dose-dependent, complete response to imatinib of a metastatic mucosal melanoma with a K642E KIT mutation
    • DOI 10.1111/j.1755-148X.2008.00475.x
    • J. Lutzky, J. Bauer, and B.C. Bastian Dose-dependent, complete response to imatinib of a metastatic mucosal melanoma with a K642E KIT mutation Pigment Cell Melanoma Res 21 2008 492 493 (Pubitemid 351990966)
    • (2008) Pigment Cell and Melanoma Research , vol.21 , Issue.4 , pp. 492-493
    • Lutzky, J.1    Bauer, J.2    Bastian, B.C.3
  • 46
    • 57049109807 scopus 로고    scopus 로고
    • Complete response of stage IV anal mucosal melanoma expressing KIT Val560Asp to the multikinase inhibitor sorafenib
    • A. Quintas-Cardama, A.J. Lazar, S.E. Woodman, K. Kim, M. Ross, and P. Hwu Complete response of stage IV anal mucosal melanoma expressing KIT Val560Asp to the multikinase inhibitor sorafenib Nat Clin Pract Oncol 5 2008 737 740
    • (2008) Nat Clin Pract Oncol , vol.5 , pp. 737-740
    • Quintas-Cardama, A.1    Lazar, A.J.2    Woodman, S.E.3    Kim, K.4    Ross, M.5    Hwu, P.6
  • 47
    • 76649108873 scopus 로고    scopus 로고
    • Anal mucosal melanoma with KIT-activating mutation and response to imatinib therapycase report and review of the literature
    • I. Satzger, U. Kuttler, B. Volker, F. Schenck, A. Kapp, and R. Gutzmer Anal mucosal melanoma with KIT-activating mutation and response to imatinib therapycase report and review of the literature Dermatology 220 2010 77 81
    • (2010) Dermatology , vol.220 , pp. 77-81
    • Satzger, I.1    Kuttler, U.2    Volker, B.3    Schenck, F.4    Kapp, A.5    Gutzmer, R.6
  • 48
    • 33646268037 scopus 로고    scopus 로고
    • Multicenter phase II trial of high-dose imatinib mesylate in metastatic melanoma: Significant toxicity with no clinical efficacy
    • DOI 10.1002/cncr.21834
    • K. Wyman, M.B. Atkins, and V. Prieto Multicenter phase II trial of high-dose imatinib mesylate in metastatic melanoma: significant toxicity with no clinical efficacy Cancer 106 2006 2005 2011 (Pubitemid 43673217)
    • (2006) Cancer , vol.106 , Issue.9 , pp. 2005-2011
    • Wyman, K.1    Atkins, M.B.2    Prieto, V.3    Eton, O.4    McDermott, D.F.5    Hubbard, F.6    Byrnes, C.7    Sanders, K.8    Sosman, J.A.9
  • 49
    • 50249141632 scopus 로고    scopus 로고
    • Phase II trial of imatinib mesylate in patients with metastatic melanoma
    • K.B. Kim, O. Eton, and D.W. Davis Phase II trial of imatinib mesylate in patients with metastatic melanoma Br J Cancer 99 2008 734 740
    • (2008) Br J Cancer , vol.99 , pp. 734-740
    • Kim, K.B.1    Eton, O.2    Davis, D.W.3
  • 51
    • 79952964600 scopus 로고    scopus 로고
    • Prediction of response to alkylator-based chemotherapy in metastatic melanoma (MM) using gene expression and promoter methylation signatures
    • H.A. Tawbi, S. Buch, and P. Pancoska Prediction of response to alkylator-based chemotherapy in metastatic melanoma (MM) using gene expression and promoter methylation signatures J Clin Oncol 27 15s 2010 abstract 9009
    • (2010) J Clin Oncol , vol.27 , Issue.15 S
    • Tawbi, H.A.1    Buch, S.2    Pancoska, P.3
  • 52
    • 27744480123 scopus 로고    scopus 로고
    • 6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea in advanced melanoma
    • DOI 10.1158/1078-0432.CCR-05-0060
    • T.F. Gajewski, J. Sosman, and S.L. Gerson Phase II trial of the O6-alkylguanine DNA alkyltransferase inhibitor O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea in advanced melanoma Clin Cancer Res 11 2005 7861 7865 (Pubitemid 41611631)
    • (2005) Clinical Cancer Research , vol.11 , Issue.21 , pp. 7861-7865
    • Gajewski, T.F.1    Sosman, J.2    Gerson, S.L.3    Liu, L.4    Dolan, E.5    Lin, S.6    Vokes, E.E.7
  • 54
    • 79551576104 scopus 로고    scopus 로고
    • A phase i study of RO4929097, a novel gamma secretase inhibitor, in patients with advanced solid tumors
    • A.W. Tolcher, S.M. Mikulski, and W.A. Messersmith A phase I study of RO4929097, a novel gamma secretase inhibitor, in patients with advanced solid tumors J Clin Oncol 28 15s 2010 abstract 2502
    • (2010) J Clin Oncol , vol.28 , Issue.15 S
    • Tolcher, A.W.1    Mikulski, S.M.2    Messersmith, W.A.3
  • 56
    • 0033819340 scopus 로고    scopus 로고
    • Epigenetic PTEN silencing in malignant melanomas without PTEN mutation
    • X.P. Zhou, O. Gimm, H. Hampel, T. Niemann, M.J. Walker, and C. Eng Epigenetic PTEN silencing in malignant melanomas without PTEN mutation Am J Pathol 157 2000 1123 1128
    • (2000) Am J Pathol , vol.157 , pp. 1123-1128
    • Zhou, X.P.1    Gimm, O.2    Hampel, H.3    Niemann, T.4    Walker, M.J.5    Eng, C.6
  • 57
    • 0033833298 scopus 로고    scopus 로고
    • Identification of PTEN mutations in metastatic melanoma specimens
    • J.T. Celebi, I. Shendrik, D.N. Silvers, and M. Peacocke Identification of PTEN mutations in metastatic melanoma specimens J Med Genet 37 2000 653 657
    • (2000) J Med Genet , vol.37 , pp. 653-657
    • Celebi, J.T.1    Shendrik, I.2    Silvers, D.N.3    Peacocke, M.4
  • 58
    • 70349556805 scopus 로고    scopus 로고
    • Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4
    • T.D. Prickett, N.S. Agrawal, and X. Wei Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4 Nat Genet 41 2009 1127 1132
    • (2009) Nat Genet , vol.41 , pp. 1127-1132
    • Prickett, T.D.1    Agrawal, N.S.2    Wei, X.3
  • 61
    • 32944460267 scopus 로고    scopus 로고
    • The WNT/beta-catenin pathway in melanoma
    • L. Larue, and V. Delmas The WNT/Beta-catenin pathway in melanoma Front Biosci 11 2006 733 742 (Pubitemid 43258176)
    • (2006) Frontiers in Bioscience , vol.11 , pp. 733-742
    • Larue, L.1    Delmas, V.2
  • 64
    • 77956045447 scopus 로고    scopus 로고
    • Melanoma-an unlikely poster child for personalized cancer therapy
    • Smalley KS, Sondak VK. Melanomaan unlikely poster child for personalized cancer therapy. N Engl J Med;363:876-8.
    • N Engl J Med , vol.363 , pp. 876-878
    • Smalley, K.S.1    Sondak, V.K.2
  • 65
    • 77953565979 scopus 로고    scopus 로고
    • Gene-expression-based prognostic assays for breast cancer
    • Kim C, Paik S. Gene-expression-based prognostic assays for breast cancer. Nat Rev Clin Oncol;7:340-7.
    • Nat Rev Clin Oncol , vol.7 , pp. 340-7
    • Kim, C.1    Paik, S.2


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