Size-dependant cellular uptake of dendritic polyglycerol

Small

Volumn 7, Issue 6, 2011, Pages 820-829

  Reichert, Stephanie ^a   Welker, Pia ^b   Calderón, Marcelo ^a   Khandare, Jayant ^a   Mangoldt, Dorothea ^b   Licha, Kai ^b   Kainthan, Rajesh K ^c   Brooks, Donald E ^c   Haag, Rainer ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b Mivenion GmbH   (Germany)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

biomedical application; dendrimer; drug delivery; nanocarriers; polyglycerols

Indexed keywords

BIOMEDICAL APPLICATIONS; CELLULAR INTERNALIZATION; CELLULAR UPTAKE; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN EPIDERMOID CARCINOMA; HUMAN LUNG CANCER CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HYPERBRANCHED; INDOCARBOCYANINE DYE; LOW MOLECULAR WEIGHT; NANOCARRIERS; POLYGLYCEROLS; SIZE RANGES; UPTAKE MECHANISM; UV-VIS SPECTROSCOPY;

CONFOCAL MICROSCOPY; CYTOLOGY; DENDRIMERS; DRUG DELIVERY; FLUORESCENCE; FLUORESCENCE SPECTROSCOPY; FUNCTIONAL POLYMERS; ULTRAVIOLET SPECTROSCOPY; ZETA POTENTIAL;

ENDOTHELIAL CELLS;

DRUG CARRIER; GLYCEROL; POLYGLYCEROL; POLYMER;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; METABOLISM; SPECTROFLUOROMETRY; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL LINE;

BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; DRUG CARRIERS; GLYCEROL; HUMANS; MOLECULAR STRUCTURE; POLYMERS; SPECTROMETRY, FLUORESCENCE;

EID: 79952968553     PISSN: 16136810     EISSN: 16136829     Source Type: Journal    
DOI: 10.1002/smll.201002220     Document Type: Article

References (40)

1. Z.-G. Li, K. Yang, Y.-A. Cao, G. Zheng, D.-P. Sun, C. Zhao, J. Yang, Int. J. Mol. Sci. 2010, 11, 1413-1422.
2. R. Weissleder, U. Mahmood, Radiology 2001, 219, 316-333.
3. H. Lee, M. K. Yu, S. Park, S. Moon, J. J. Min, Y. Y. Jeong, H.-W. Kang, S. Jon, J. Am. Chem. Soc. 2007, 129, 12739-12745.
4. Y. Hama, Y. Urano, Y. Koyama, M. Bernardo, P. L. Choyke, H. Kobayashi, Bioconj. Chem. 2006, 17, 1426-1431.
5. Z. Yang, S. Zheng, W. J. Harrison, J. Harder, X. Wen, J. G. Gelovani, A. Qiao, C. Li, Biomacromolecules 2007, 8, 3422-3428.
6. Y. Matsumura, H. Maeda, Cancer Res. 1986, 46, 6387-6392.
7. H. Maeda, J. Wu, T. Sawa, Y. Matsumura, K. Hori, J. Control. Release 2000, 65, 271-284.
8. R. K. Jain, Cancer Metathesis Rev. 1987, 6, 559-593.
9. R. K. Jain, Cancer Res. 1987, 47, 3039-3051.
10. M. Müllner, A. Schallon, A. Walther, R. Freitag, A. H. E. Müller, Biomacromolecules 2010, 11, 390-396.
11. R. Haag, F. Kratz, Angew. Chem. 2006, 118, 1218-1237.
12. M. Calderón, M. A. Quadir, S. K. Sharma, R. Haag, Adv. Mater. 2010, 22, 190-218.
13. M. Calderón, R. Graeser, F. Kratz, R. Haag, Bioorg. Med. Chem. Lett. 2009, 19, 3725-3728.
14. R. K. Kainthan, S. R. Hestera, E. Levin, D. V. Devine, D. E. Brooks, Biomaterials 2007, 28, 4581-4590.
15. W. Baumgartner, B. Jäckli, in Nanotechnologie in der Medizin, 1st ed., Springer, Vienna, Austria 2007.
16. A. K. Iyer, G. Khaled, J. Fang, H. Maeda, Drug Discov. Today 2006, 11, 812-818.
17. R. J. Amir, N. Pessah, M. Shamis, D. Shabat, Angew. Chem. Int. Ed. 2003, 42, 4494-4499.
18. S. Li, M. L. Szalai, R. M. Kevwitch, D. V. McGrath, Am. Chem. Soc. 2003, 125, 10516-10517.
19. M. J. Liu, J. M. J. Fréchet, Pharm. Sci. Technol. Today 1999, 2, 393-401.
20. D. A. Tomalia, L. A. Reyna, S. Svenson, Biochem. Soc. Trans. 2007, 35, 61-67.
21. C. Gao, D. Yan, Prog. Polym. Sci. 2004, 29, 183-275.
22. A. Sunder, R. Mülhaupt, R. Haag, H. Frey, Adv. Mater. 2000, 12, 235-239.
23. A. Sunder, R. Hanselmann, H. Frey, R. Mülhaupt, Macromolecules 1999, 32, 4240-4246.
24. C. C. Lee, J. A. MacKay, J. M. J. Fréchet, F. C. Szoka, Nat. Biotechnol. 2005, 23, 1517-1526.
25. P. Kolhe, J. Khandare, O. Pillai, S. Kannan, M. Lieh-Lai, R. M. Kannan, Biomaterials 2006, 27, 660-669.
26. J. Khandare, A. Mohr, M. Calderón, P. Welker, K. Licha, R. Haag, Biomaterials 2010, 31, 4268-4277.
27. M. Calderón, P. Welker, K. Licha, I. Fitchner, R. Graeser, R. Haag, F. Kratz, J. Control. Release 2011, DOI:10.1016/j.jconrel.2011.01.017.
28. J. Dernedde, A. Rausch, M. Weinhart, S. Enders, R. Tauber, K. Licha, M. Schirner, U. Zügel, A. von Bonin, R Haag, Proc. Natl. Acad. Sci. USA 2010, 107, 19679-19684.
29. R. Haag, H. Frey, Rev. Mol. Biotechnol. 2002, 90, 257-267.
30. S. K. Rodal, G. Skretting, O. Garred, F. Vilhardt, B. van Deurs, K. Sandvig, Mol. Biol. Cell 1999, 10, 961-974.
31. J. Z. Rappoport, S. M. Simon, J. Cell Sci. 2002, 116, 847-855.
32. S. J. Doxsey, F. M. Brodsky, G. S. Blank, A. Helenius, Cell 1987, 50, 453-463.
33. O. Shupliakov, Neuroscience 2009, 158, 204-210.
34. J. B. Hughes, C. Berger, M. S. Rodland, M. Hasmann, E. Stang, I. H. Madshus, Mol. Cancer Ther. 2009, 8, 1885-1892.
35. G. Sahay, V. Gautam, R. Luxenhofer, A. V. Kabanov, Biomaterials 2010, 31, 1757-1764.
36. M. Saad, O. B. Garbuzenko, E. Ber, P. Chandna, J. J. Khandare, V. P. Pozharov, T. Minko, J. Control. Release 2008, 130, 107-114.
37. V. P. Torchilin, Nat. Rev. 2005, 4, 145-160.
38. M. Hesse, H. Meier, B. Zeeh, in Spektroskopische Methoden in der organischen, Chemie, 7th ed., Thieme Georg Verlag, Germany 2005.
39. Y. G. Gololobov, I. N. Zhmurova, L. F. Kasukhin, Tetrahedron 1981, 37, 437-472.
40. K. Licha, C. Hessenius, A. Becker, P. Henklein, M. Bauer, S. Wisniewski, B. Wiedenmann, W. Semmler, Bioconj. Chem. 2001, 12, 44-50.