Synthesis, characterization, and biological properties of cyanine-labeled somatostatin analogues as receptor-targeted fluorescent probes

Bioconjugate Chemistry

Volumn 12, Issue 1, 2001, Pages 44-50

  Licha, K ^a,b   Hessenius, C ^b   Becker, A ^a,b   Henklein, P ^b   Bauer, M ^a,b   Wisniewski, S ^a,b   Wiedenmann, B ^b   Semmler, W ^a,b  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b HUMBOLDT UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCENCE IMAGING; FLUORESCENCE MICROSCOPY; INFRARED DEVICES; MOLECULAR IMAGING; OPTICAL IMAGE STORAGE; SYNTHESIS (CHEMICAL);

BIOLOGICAL PROPERTIES; CYANINE DYES; FLUORESCENCE QUANTUM YIELD; FLUORESCENT PROBES; MOLAR ABSORBANCES; N-TERMINALS; SOLID PHASE SYNTHESIS; SOMATOSTATIN RECEPTORS; SYNTHESIS AND CHARACTERIZATIONS; TERMINAL AMINO GROUPS;

PEPTIDES;

ANIMALIA;

EID: 0035142180     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc000040s     Document Type: Article

References (28)

1. Neuropeptide receptors in health and disease: The molecular basis for in vivo imaging
2. Regulatory peptide receptors as molecular targets for cancer diagnosis and therapy
3. Somatostatin-receptor imaging in the localization of endocrine tumors
4. Vasoactive intestinal peptide-receptor imaging for the localization of intestinal adenocarcinomas and endocrine tumors
5. 3]-octreotide: The Rotterdam experience with more than 1,000 patients
6. Molecular biology of somatostatin receptors
7. Somatostatin
8. Somatostatin
9. Expression and localization of somatostatin receptor SSTR1, SSTR2, and SSTR3 messenger RNAs in primary human tumors using in situ hybridization
10. Somatostatin receptor subtypes sst1, sst2, sst3 and sst5 expression in human pituitary, gastroentero-pancreatic and mammary tumors: Comparison of mRNA analysis with receptor autoradiography
11. Immunohistochemical localization of somatostatin receptors sst2A in human tumors
12. Somatostatin and somatostatin analogue (SMS 201-995) in treatment of hormone-secreting tumors of the pituitary and gastrointestinal tract and nonneoplastic diseases of the gut
13. Internalization of indium-111 into human neuroendocrine tumor cells after incubation with indium-111-DTPA-D-Phe1-octreotide
14. 3]-octreotide: Peptides for somatostatin receptor-targeted scintigraphy and radionuclide therapy
15. Time-resolved transillumination and optical tomography
16. In vivo fluorescence spectroscopy and imaging for oncological applications
17. In vivo characterization of cyanine dyes as contrast agents for near-infrared imaging
18. Imaging of spontaneous canine mammary tumors using fluorescent contrast agents
19. Cyanine fluorochrome-labeled antibodies in vivo: Assessment of tumor imaging using Cy3, Cy5, Cy5.5, and Cy7
20. In vivo imaging of tumors with protease-activated near-infrared fluorescent probes
21. Cyanine dye labeling reagents containing isothiocyanate groups
22. Synthesis of squaraine-N-hydroxy-succinimide esters and their biological application as long-wavelength fluorescent labels
23. Absorption and fluorescence properties of cyanine dyes
24. Continuous, clonal, insulin- and somatostatin-secreting cell lines established from a transplantable rat islet cell tumor
25. A new method for the synthesis of heptmethine cyanine dyes: Synthesis of new near-infrared fluorescent labels
26. Cyanine-labeling reagents: Sulfobenzindocyanine succinimidyl esters
27. Functionalized tricarbocyanine dyes as near-infrared fluorescent probes for biomolecules
28. Preparation of a cathepsin D sensitive near-infrared fluorescence probe for imaging