In vivo study of the effects of peptide-conjugated near-infrared fluorescent quantum dots on the tumorigenic and lymphatic metastatic capacities of squamous cell carcinoma cell line Tca8113 and U14

International Journal of Molecular Sciences

Volumn 11, Issue 4, 2010, Pages 1413-1422

  Li, Zhi Gang ^a   Yang, Kai ^a   Cao, Yu An ^a   Zheng, Gang ^b   Sun, De Ping ^a   Zhao, Cheng ^a   Yang, Jia ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b Chongqing Hospital of Traditional Chinese Medicine   (China)

Author keywords

Apoptosis; Growth; Metastasis; Near infrared fluorescence; Peptide; Proliferation; Quantum dots; Tumor

Indexed keywords

QUANTUM DOT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CARCINOGENESIS; CARCINOGENICITY; CELL GROWTH; CELL LABELING; CELL PROLIFERATION; CERVICAL LYMPH NODE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; LYMPH NODE METASTASIS; METASTASIS POTENTIAL; MOUSE; NEAR INFRARED SPECTROSCOPY; NON INVASIVE MEASUREMENT; NONHUMAN; SQUAMOUS CELL CARCINOMA;

APOPTOSIS; GROWTH; METASTASIS; NEAR-INFRARED FLUORESCENCE; PEPTIDE; PROLIFERATION; QUANTUM DOTS; TUMOR;

ANIMALS; APOPTOSIS; CARCINOGENICITY TESTS; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL PROLIFERATION; FEMALE; HUMANS; LYMPHATIC METASTASIS; MICE; MICE, INBRED BALB C; MICE, NUDE; PEPTIDES; QUANTUM DOTS; SPECTROSCOPY, NEAR-INFRARED; TONGUE NEOPLASMS; TRANSPLANTATION, HETEROLOGOUS;

EID: 77951887226     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms11041413     Document Type: Article

References (22)

1. Jaiswal, J.K.; Mattoussi, H.; Mauro, J.M.; Simon, S.M. Long-term multiple color imaging of live cells using quantum dot bioconjugates. Nat. Biotechnol. 2003, 21, 47-51.
2. Tanke, H.J.; Dirks, R.W.; Raap, T. FISH and immunocytochemistry: towards visualising single target molecules in living cells. Curr. Opin. Biotechnol. 2005, 16, 49-54.
3. Walling, M.A.; Novak, J.A.; Shepard, J.R. Quantum Dots for live cell and in vivo imaging. Int. J. Mol. Sci. 2009, 10, 441-491
4. Medintz, I.L.; Uyeda, H.T.; Goldman, E.R.; Mattoussi, H. Quantum dot bioconjugates for imaging, labelling and sensing. Nat. Mater. 2005, 4, 435-446.
5. Ryman-Rasmussen, J.P.; Riviere, J.E.; Monteiro-Riviere, N.A. Penetration of intact skin by quantum dots with diverse physicochemical properties. Toxicol. Sci. 2006, 91, 159-165.
6. Han, M.; Gao, X.; Su, J.Z.; Nie, S. Quantum-dot-tagged microbeads for multiplexed optical coding of biomolecules. Nat. Biotechnol. 2001, 19, 631-635.
7. Wu, X.; Liu, H.; Liu, J.; Haley, K.N.; Treadway, J.A.; Larson, J.P.; Ge, N.; Peale, F.; Bruchez, M.P. Immunofluorescent labeling of cancer marker Her2 and other cellular targets with semiconductor quantum dots. Nat. Biotechnol. 2003, 21, 41-46.
8. Michalet, X.; Pinaud, F.F.; Bentolila, L.A.; Tsay, J.M.; Doose, S.; Li, J.J.; Sundaresan, G.; Wu, A.M.; Gambhir, S.S.; Weiss, S. Quantum dots for live cells, in vivo imaging, and diagnostics. Science 2005, 307, 538-544.
9. Zimmer, J.P.; Kim, S.W.; Ohnishi, S.; Tanaka, E.; Frangioni, J.V.; Bawendi, M.G. Size series of small indium arsenide-zinc selenide core-shell nanocrystals and their application to in vivo imaging. J. Am. Chem. Soc. 2006, 128, 2526-2527.
10. Gao, X.; Cui, Y.; Levenson, R.M.; Chung, L.W.; Nie, S. In vivo cancer targeting and imaging with semiconductor quantum dots. Nat. Biotechnol. 2004, 22, 969-976.
11. Jiang, W.; Singhal, A.; Kim, B.Y.S.; Zheng, J.; Rutka, J.T.; Wang, C.; Chan, W.C.W. Assessing near-infrared quantum dots for deep tissue, organ, and animal imaging applications. J. Assoc. Lab. Autom. 2008, 13, 6-12.
12. Tada, H.; Higuchi, H.; Wanatabe, T.M.; Ohuchi, N. In vivo Real-time tracking of single quantum dots conjugated with monoclonal anti-HER2 antibody in tumors of mice. Cancer Res. 2007, 67, 1138-1144.
13. Shi, C.; Zhu, Y.; Xie, Z.; Qian, W.; Hsieh, C.L.; Nie, S.; Su, Y.; Zhau, H.E.; Chung, L.W. Visualizing human prostate cancer cells in mouse skeleton using bioconjugated near- infrared fluorescent quantum dots. Urology 2009, 74, 446-51
14. Voura, E.B.; Jaiswal, J.K.; Mattoussi, H.; Simon, S.M. Tracking metastatic tumor cell extravasation with quantum dot nanocrystalsand fluorescence emission-scanning microscopy. Nat. Med. 2004, 10, 993-998.
15. Frangioni, J.V.; Kim, S.W.; Ohnishi, S.; Bawendi, M.G. Sentinel lymph node mapping with type II quantum dots. Methods Mol. Biol. 2007, 374, 147-159.
16. Ballou, B.; Ernst, L.A.; Andreko, S.; Harper, T.; Fitzpatrick, J.A.J.; Waggoner, A.S.; Bruchez, M.P. Sentinel lymph node imaging using quantum dots in mouse tumor models. Bioconj. Chem. 2007, 18, 389-396.
17. Cai, W.; Shin, D.W.; Chen, K.; Gheysens, O.; Cao, Q.; Wang, S.X.; Gambhir, S.S.; Chen, X. Peptide-labeled near-infrared quantum dots for imaging tumor vasculature in living subjects. Nano. Lett. 2006, 6, 6669-6676.
18. Yang, K.; Li, Z.; Cao, Y.; Yu, X.; Mei, J. Effect of peptide-conjugated near-infrared fluorescent quantum dots (NIRF-QDs) on the invasion and metastasis of human tongue squamous cell carcinoma cell line tca8113 in vitro. Int. J. Mol. Sci. 2009, 10, 4418-4427.
19. Chen, B.; Liu, Q.; Zhang, Y.; Xu, L.; Fang, X. Transmembrane delivery of the cell-penetrating peptide conjugated semiconductor quantum dots. Langmuir 2008, 24, 11866-11871.
20. Lin, S.; Xie, X.; Patel, M.R.; Yang, Y.H.; Li, Z.; Cao, F.; Gheysens, O.; Zhang, Y.; Gambhir, S.S.; Rao, J.H.; Wu, J.C. Quantum dot imaging for embryonic stem cells. BMC Biotechnol. 2007, 7, 67-77.
21. Ruan, G.; Agrawal, A.; Marcus, A.I.; Nie, S. Imaging and tracking of tat peptide-conjugated quantum dots in living cells: New insights into nanoparticle uptake, intracellular transport, and vesicle shedding. J. Am. Chem. Sco. 2007, 129, 14759-14766.
22. Lei, Y.; Tang, H.; Yao, L.; Yu, R.; Feng, M.; Zou, B. Applications of mesenchymal stem cells labeled with Tat peptide conjugated quantum dots to cell tracking in mouse body. Bioconjug. Chem. 2008, 19, 421-427.