Targeting adenovirus gene delivery to activated tumour-associated vasculature via endothelial selectins

Journal of Controlled Release

Volumn 150, Issue 2, 2011, Pages 196-203

  Bachtarzi, Houria ^a   Stevenson, Mark ^a   Šubr, Vladimir ^b   Ulbrich, Karel ^b   Seymour, Leonard W ^a   Fisher, Kerry D ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b INSTITUTE OF MACROMOLECULAR CHEMISTRY   (Czech Republic)

Author keywords

Adenovirus; Cancer; E selectin; pHPMA; Vascular targeting

Indexed keywords

ADENOVIRUS; CANCER; PHPMA; SELECTINS; VASCULAR TARGETING;

BACTERIOPHAGES; DISEASES; ENDOTHELIAL CELLS; GENE THERAPY; GENE TRANSFER; GLYCOPROTEINS; LIGANDS; MONOCLONAL ANTIBODIES; OPTIMIZATION; PLANTS (BOTANY); PROTEINS; SELF ASSEMBLY;

TUMORS;

ADENOVIRUS VECTOR; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; LUCIFERASE; P SELECTIN GLYCOPROTEIN LIGAND 1; POLY [N (2-HYDROXYPROPYL)METHACRYLAMIDE]; POLYMER; PROTEIN G; SELECTIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ENDOTHELIUM CELL; FEMALE; GENE TARGETING; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; TUMOR CELL; VASCULARIZATION; VIRAL GENE DELIVERY SYSTEM;

ACRYLAMIDES; ADENOVIRIDAE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD31; BACTERIAL PROTEINS; CELL LINE, TUMOR; CELLS, CULTURED; E-SELECTIN; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; FEMALE; GENE TRANSFER TECHNIQUES; HEP G2 CELLS; HUMANS; LUCIFERASES, FIREFLY; MEMBRANE GLYCOPROTEINS; MICE; MICE, NUDE; NEOPLASMS; P-SELECTIN; SELECTINS; TRANSDUCTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA; UMBILICAL CORD; VIRAL LOAD; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 79952932483     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2010.10.011     Document Type: Article

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