Examination of glucose transporter-1, transforming growth factor-β and neuroglobin immunoreactivity in the orbitofrontal cortex in late-life depression

Psychiatry and Clinical Neurosciences

Volumn 65, Issue 2, 2011, Pages 158-164

  Khundakar, Ahmad ^a   Morris, Christopher ^a   Slade, Janet ^a   Thomas, Alan J ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

depression; elderly; immunohistochemistry; orbitofrontal cortex; vascular

Indexed keywords

CYTOKINE; GLUCOSE TRANSPORTER 1; NEUROGLOBIN; TRANSFORMING GROWTH FACTOR BETA;

AGED; ARTICLE; COMPUTER PROGRAM; CONTROLLED STUDY; DEPRESSION; DISEASE ASSOCIATION; FEMALE; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; ORBITAL CORTEX; PROTEIN EXPRESSION;

AGED; DEPRESSION; FEMALE; FRONTAL LOBE; GLOBINS; GLUCOSE TRANSPORTER TYPE 1; HUMANS; MALE; NERVE TISSUE PROTEINS; TRANSFORMING GROWTH FACTOR BETA;

EID: 79952929945     PISSN: 13231316     EISSN: 14401819     Source Type: Journal    
DOI: 10.1111/j.1440-1819.2010.02176.x     Document Type: Article

References (42)

1. Alexopoulos GS, Meyers BS, Young RC, Kakuma T, Silbersweig D, Charlson M,. Clinically defined vascular depression. Am. J. Psychiatry 1997; 154: 562-565. (Pubitemid 27147616)
2. Maes M, Bosmans E, Meltzer HY, Scharpe S, Suy E,. Interleukin-1 beta: a putative mediator of HPA axis hyperactivity in major depression? Am. J. Psychiatry 1993; 150: 1189-1193. (Pubitemid 23218899)
3. Maes M, Meltzer HY, Bosmans E, et al,. Increased plasma concentrations of interleukin-6, soluble interleukin-6, soluble interleukin-2 and transferrin receptor in major depression. J. Affect. Disord. 1995; 34: 301-309.
4. Mikova O, Yakimova R, Bosmans E, Kenis G, Maes M,. Increased serum tumor necrosis factor alpha concentrations in major depression and multiple sclerosis. Eur. Neuropsychopharmacol. 2001; 11: 203-208. (Pubitemid 32611587)
5. Thomas AJ, Davis S, Morris C, Jackson E, Harrison R, O'Brien JT,. Increase in interleukin-1beta in late-life depression. Am. J. Psychiatry 2005; 162: 175-177.
6. O'Brien JT, Ames D, Schweitzer I, Colman P, Desmond P, Tress B,. Clinical and magnetic resonance imaging correlates of hypothalamic-pituitary-adrenal axis function in depression and Alzheimer's disease. Br. J. Psychiatry 1996; 168: 679-687.
7. Ballmaier M, Toga AW, Blanton RE, et al,. Anterior cingulate, gyrus rectus, and orbitofrontal abnormalities in elderly depressed patients: an MRI-based parcellation of the prefrontal cortex. Am. J. Psychiatry 2004; 161: 99-108. (Pubitemid 38419314)
8. Bremner JD, Vythilingam M, Vermetten E, et al,. Reduced volume of orbitofrontal cortex in major depression. Biol. Psychiatry 2002; 51: 273-279. (Pubitemid 34214992)
9. Galynker II, Cai J, Ongseng F, Finestone H, Dutta E, Serseni D,. Hypofrontality and negative symptoms in major depressive disorder. J. Nucl. Med. 1998; 39: 608-612. (Pubitemid 28175832)
10. Taylor WD, Steffens DC, McQuoid DR, et al,. Smaller orbital frontal cortex volumes associated with functional disability in depressed elders. Biol. Psychiatry 2003; 53: 144-149. (Pubitemid 36126477)
11. Vivien D, Ali C,. Transforming growth factor-beta signalling in brain disorders. Cytokine Growth Factor Rev. 2006; 17: 121-128. (Pubitemid 43117521)
12. Lee KM, Kim YK,. The role of IL-12 and TGF-beta1 in the pathophysiology of major depressive disorder. Int. Immunopharmacol. 2006; 6: 1298-1304.
13. Kim YK, Na KS, Shin KH, Jung HY, Choi SH, Kim JB,. Cytokine imbalance in the pathophysiology of major depressive disorder. Prog. Neuropsychopharmacol. Biol. Psychiatry 2007; 31: 1044-1053.
14. Sun Y, Jin K, Mao XO, Zhu Y, Greenberg DA,. Neuroglobin is up-regulated by and protects neurons from hypoxic-ischemic injury. Proc. Natl. Acad. Sci. USA 2001; 98: 15306-15311. (Pubitemid 34014010)
15. Sun Y, Jin K, Peel A, Mao XO, Xie L, Greenberg DA,. Neuroglobin protects the brain from experimental stroke in vivo. Proc. Natl. Acad. Sci. USA 2003; 100: 3497-3500. (Pubitemid 36356612)
16. Khan AA, Wang Y, Sun Y, et al,. Neuroglobin-overexpressing transgenic mice are resistant to cerebral and myocardial ischemia. Proc. Natl. Acad. Sci. USA 2006; 103: 17944-17948. (Pubitemid 44852265)
17. Mooradian AD, Chung HC, Shah GN,. GLUT-1 expression in the cerebra of patients with Alzheimer's disease. Neurobiol. Aging 1997; 18: 469-474. (Pubitemid 27497142)
18. Rosenstein JM, Mani N, Silverman WF, Krum JM,. Patterns of brain angiogenesis after vascular endothelial growth factor administration in vitro and in vivo. Proc. Natl. Acad. Sci. USA 1998; 95: 7086-7091. (Pubitemid 28278111)
19. Wei L, Erinjeri JP, Rovainen CM, Woolsey TA,. Collateral growth and angiogenesis around cortical stroke. Stroke 2001; 32: 2179-2184. (Pubitemid 32868119)
20. Thomas AJ, Ferrier IN, Kalaria RN, Davis S, O'Brien JT,. Cell adhesion molecule expression in the dorsolateral prefrontal cortex and anterior cingulate cortex in major depression in the elderly. Br. J. Psychiatry 2002; 181: 129-134. (Pubitemid 34864494)
21. Thomas AJ, Ferrier IN, Kalaria RN, et al,. Elevation in late-life depression of intercellular adhesion molecule-1 expression in the dorsolateral prefrontal cortex. Am. J. Psychiatry 2000; 157: 1682-1684.
22. Perry EH,. Coronal Maps of Brodmann Areas in the Human Brain. Wolfe, London, 1993.
23. Hellstrom-Lindahl E, Court J, Keverne J, et al,. Nicotine reduces A beta in the brain and cerebral vessels of APPsw mice. Eur. J. Neurosci. 2004; 19: 2703-2710. (Pubitemid 38746387)
24. Gundersen HJ, Jensen EB,. The efficiency of systematic sampling in stereology and its prediction. J. Microsc. 1987; 147: 229-263.
25. Harik N, Harik SI, Kuo NT, Sakai K, Przybylski RJ, LaManna JC,. Time-course and reversibility of the hypoxia-induced alterations in cerebral vascularity and cerebral capillary glucose transporter density. Brain Res. 1996; 737: 335-338. (Pubitemid 26366635)
26. Takagi H, King GL, Aiello LP,. Hypoxia upregulates glucose transport activity through an adenosine-mediated increase of GLUT1 expression in retinal capillary endothelial cells. Diabetes 1998; 47: 1480-1488. (Pubitemid 28396953)
27. Harik SI, Behmand RA, LaManna JC,. Hypoxia increases glucose transport at blood-brain barrier in rats. J. Appl. Physiol. 1994; 77: 896-901. (Pubitemid 24258328)
28. Boado RJ,. Brain-derived peptides increase blood-brain barrier GLUT1 glucose transporter gene expression via mRNA stabilization. Neurosci. Lett. 1998; 255: 147-150. (Pubitemid 28506023)
29. Wahl SM,. Transforming growth factor-beta: innately bipolar. Curr. Opin. Immunol. 2007; 19: 55-62. (Pubitemid 46073697)
30. Krupinski J, Kumar P, Kumar S, Kaluza J,. Increased expression of TGF-beta 1 in brain tissue after ischemic stroke in humans. Stroke 1996; 27: 852-857. (Pubitemid 26142515)
31. Knuckey NW, Finch P, Palm DE, et al,. Differential neuronal and astrocytic expression of transforming growth factor beta isoforms in rat hippocampus following transient forebrain ischemia. Brain Res. Mol. Brain Res. 1996; 40: 1-14. (Pubitemid 26241780)
32. Ata KA, Lennmyr F, Funa K, Olsson Y, Terent A,. Expression of transforming growth factor-beta1, 2, 3 isoforms and type I and II receptors in acute focal cerebral ischemia: an immunohistochemical study in rat after transient and permanent occlusion of middle cerebral artery. Acta Neuropathol. 1999; 97: 447-455. (Pubitemid 29195107)
33. Harvey BK, Hoffer BJ, Wang Y,. Stroke and TGF-beta proteins: glial cell line-derived neurotrophic factor and bone morphogenetic protein. Pharmacol. Ther. 2005; 105: 113-125.
34. Kim JS,. Cytokines and adhesion molecules in stroke and related diseases. J. Neurol. Sci. 1996; 137: 69-78. (Pubitemid 26172036)
35. Laufs TL, Wystub S, Reuss S, Burmester T, Saaler-Reinhardt S, Hankeln T,. Neuron-specific expression of neuroglobin in mammals. Neurosci. Lett. 2004; 83-86. (Pubitemid 38759073)
36. Mammen PP, Shelton JM, Goetsch SC, et al,. Neuroglobin, a novel member of the globin family, is expressed in focal regions of the brain. J. Histochem. Cytochem. 2002; 50: 1591-1598. (Pubitemid 36078124)
37. Rajkowska G, Miguel-Hidalgo JJ, Wei J, et al,. Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression. Biol. Psychiatry 1999; 45: 1085-1098. (Pubitemid 29236550)
38. Khundakar A, Morris C, Oakley A, Thomas AJ,. A morphometric examination of neuronal and glial cell pathology in the orbitofrontal cortex in late-life depression. Int. Psychogeriatr. 2010 (in press).
39. Khundakar AA, Morris CM, Oakley AE, McMeekin W, Thomas AJ,. Morphometric analysis of neuronal and glial cell pathology in the dorsolateral prefrontal cortex in late-life depression. Br. J. Psychiatry 2009; 195: 163-169.
40. Drevets WC,. Orbitofrontal cortex function and structure in depression. Ann. N. Y. Acad. Sci. 2007; 1121: 499-527.
41. Egger K, Schocke M, Weiss E, et al,. Pattern of brain atrophy in elderly patients with depression revealed by voxel-based morphometry. Psychiatry Res. 2008; 164: 237-244.
42. Thomas AJ, O'Brien JT, Davis S, et al,. Ischemic basis for deep white matter hyperintensities in major depression: a neuropathological study. Arch. Gen. Psychiatry 2002; 59: 785-792. (Pubitemid 35001143)