-
1
-
-
67650874081
-
Cancer statistics, 2009
-
Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2009. CA Cancer J Clin 2009; 59: 225-249.
-
(2009)
CA Cancer J Clin
, vol.59
, pp. 225-249
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
-
2
-
-
14944385553
-
Global cancer statistics, 2002
-
Parkin DM, Bray F, Ferlay J, Pisani P,. Global cancer statistics, 2002. CA Cancer J Clin 2005; 55: 74-108. (Pubitemid 40372904)
-
(2005)
Ca-A Cancer Journal for Clinicians
, vol.55
, Issue.2
, pp. 74-108
-
-
Parkin, D.M.1
Bray, F.2
Ferlay, J.3
Pisani, P.4
-
3
-
-
79952913163
-
-
SEER Stat Database: Incidence-SEER 17 Regs Limited-Use, Nov 2006 Sub (1973-2004 varying), National Cancer Institute, DCCPS, Surveillance Research Program, Cancer Statistics Branch, released April 2007, based on the November 2006 submission. 2007. Surveillance, Epidemiology, and End Results (SEER) Program. Available at
-
SEER Stat Database: Incidence-SEER 17 Regs Limited-Use, Nov 2006 Sub (1973-2004 varying), National Cancer Institute, DCCPS, Surveillance Research Program, Cancer Statistics Branch, released April 2007, based on the November 2006 submission. 2007. Surveillance, Epidemiology, and End Results (SEER) Program. Available at: http://www.seer.cancer.gov
-
-
-
-
4
-
-
33846949310
-
Molecular genetics of premalignant oral lesions
-
Mithani SK, Mydlarz WK, Grumbine FL, Smith IM, Califano JA,. Molecular genetics of premalignant oral lesions. Oral Dis 2007; 13: 126-133.
-
(2007)
Oral Dis
, vol.13
, pp. 126-133
-
-
Mithani, S.K.1
Mydlarz, W.K.2
Grumbine, F.L.3
Smith, I.M.4
Califano, J.A.5
-
5
-
-
33846144159
-
Clinical, pathological, cellular and molecular lesions caused by oral smokeless tobacco - A review
-
DOI 10.1111/j.1600-0714.2007.00496.x
-
Warnakulasuriya KA, Ralhan R,. Clinical, pathological, cellular and molecular lesions caused by oral smokeless tobaccoâ€"a review. J Oral Pathol Med. 2007; 36: 63-77. (Pubitemid 46089306)
-
(2007)
Journal of Oral Pathology and Medicine
, vol.36
, Issue.2
, pp. 63-77
-
-
Warnakulasuriya, K.A.A.S.1
Ralhan, R.2
-
6
-
-
69149098253
-
Signal transducer and activator of transcription-3, inflammation, and cancer: How intimate is the relationship?
-
Aggarwal BB, Kunnumakkara AB, Harikumar KB, et al. Signal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship? Ann N Y Acad Sci 2009; 1171: 59-76.
-
(2009)
Ann N y Acad Sci
, vol.1171
, pp. 59-76
-
-
Aggarwal, B.B.1
Kunnumakkara, A.B.2
Harikumar, K.B.3
-
7
-
-
70350500225
-
STATs in cancer inflammation and immunity: A leading role for STAT3
-
Yu H, Pardoll D, Jove R,. STATs in cancer inflammation and immunity: a leading role for STAT3. Nat Rev Cancer 2009; 9: 798-809.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 798-809
-
-
Yu, H.1
Pardoll, D.2
Jove, R.3
-
8
-
-
28544438023
-
Activated epidermal growth factor receptor-stat-3 signaling promotes tumor survival in vivo in non-small cell lung cancer
-
DOI 10.1158/1078-0432.CCR-05-0827
-
Haura EB, Zheng Z, Song L, Cantor A, Bepler G,. Activated epidermal growth factor receptor-Stat-3 signaling promotes tumor survival in vivo in non-small cell lung cancer. Clin Cancer Res 2005; 11: 8288-8294. (Pubitemid 41746939)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.23
, pp. 8288-8294
-
-
Haura, E.B.1
Zheng, Z.2
Song, L.3
Cantor, A.4
Bepler, G.5
-
9
-
-
85047695527
-
Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis
-
DOI 10.1038/sj/onc/1205260
-
Niu G, Wright KL, Huang M, et al. Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis. Oncogene 2002; 21: 2000-2008. (Pubitemid 34270888)
-
(2002)
Oncogene
, vol.21
, Issue.13
, pp. 2000-2008
-
-
Niu, G.1
Wright, K.L.2
Huang, M.3
Song, L.4
Haura, E.5
Turkson, J.6
Zhang, S.7
Wang, T.8
Sinibaldi, D.9
Coppola, D.10
Heller, R.11
Ellis, L.M.12
Karras, J.13
Bromberg, J.14
Pardoll, D.15
Jove, R.16
Yu, H.17
-
10
-
-
85047699589
-
Constitutive of Stat3α in brain tumors: Localization to tumor endothelial cells and activation by the endothelial tyrosine kinase receptor (VEGFR-2)
-
DOI 10.1038/sj/onc/1205263
-
Schaefer LK, Ren Z, Fuller GN, Schafer TS,. Constitutive activation of Stat3alpha in brain tumors: localization to tumor endothelial cells and activation by the endothelial tyrosine kinase receptor (VEGFR-2). Oncogene 2002; 21: 2058-2065. (Pubitemid 34270894)
-
(2002)
Oncogene
, vol.21
, Issue.13
, pp. 2058-2065
-
-
Schaefer, L.K.1
Ren, Z.2
Fuller, G.N.3
Schaefer, T.S.4
-
11
-
-
34247154498
-
A novel inhibitor of the STAT3 pathway induces apoptosis in malignant glioma cells both in vitro and in vivo
-
DOI 10.1038/sj.onc.1210031, PII 1210031
-
Iwamaru A, Szymanski S, Iwado E, et al. A novel inhibitor of the STAT3 pathway induces apoptosis in malignant glioma cells both in vitro and in vivo. Oncogene 2007; 26: 2435-2444. (Pubitemid 46597261)
-
(2007)
Oncogene
, vol.26
, Issue.17
, pp. 2435-2444
-
-
Iwamaru, A.1
Szymanski, S.2
Iwado, E.3
Aoki, H.4
Yokoyama, T.5
Fokt, I.6
Hess, K.7
Conrad, C.8
Madden, T.9
Sawaya, R.10
Kondo, S.11
Priebe, W.12
Kondo, Y.13
-
12
-
-
31544460437
-
Activation of Stat3 in primary tumors from high-risk breast cancer patients is associated with elevated levels of activated Src and survivin expression
-
DOI 10.1158/1078-0432.CCR-04-1749
-
Diaz N, Minton S, Cox C, et al. Activation of stat3 in primary tumors from high-risk breast cancer patients is associated with elevated levels of activated SRC and survivin expression. Clin Cancer Res 2006; 12: 20-28. (Pubitemid 43166171)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.1
, pp. 20-28
-
-
Diaz, N.1
Minton, S.2
Cox, C.3
Bowman, T.4
Gritsko, T.5
Garcia, R.6
Eweis, I.7
Wloch, M.8
Livingston, S.9
Seijo, E.10
Cantor, A.11
Lee, J.-H.12
Beam, C.A.13
Sullivan, D.14
Jove, R.15
Muro-Cacho, C.A.16
-
13
-
-
70350345008
-
Significance of promoter hypermethylation of p16 gene for margin assessment in carcinoma tongue
-
Sinha P, Bahadur S, Thakar A, et al. Significance of promoter hypermethylation of p16 gene for margin assessment in carcinoma tongue. Head Neck 2009; 31: 1423-1430.
-
(2009)
Head Neck
, vol.31
, pp. 1423-1430
-
-
Sinha, P.1
Bahadur, S.2
Thakar, A.3
-
14
-
-
33750496435
-
Stat3 expression in oral squamous cell carcinoma: Association with clinicopathological parameters and survival
-
Shah NG, Trivedi TI, Tankshali RA, et al. Stat3 expression in oral squamous cell carcinoma: association with clinicopathological parameters and survival. Int J Biol Markers 2006; 21: 175-183. (Pubitemid 44660290)
-
(2006)
International Journal of Biological Markers
, vol.21
, Issue.3
, pp. 175-183
-
-
Shah, N.G.1
Trivedi, T.I.2
Tankshali, R.A.3
Goswami, J.A.4
Jetly, D.H.5
Kobawala, T.P.6
Shukla, S.N.7
Shah, P.M.8
Verma, R.J.9
-
15
-
-
34447300416
-
Molecular alterations in oral carcinogenesis: Significant risk predictors in malignant transformation and tumor progression
-
Shah NG, Trivedi TI, Tankshali RA, et al. Molecular alterations in oral carcinogenesis: significant risk predictors in malignant transformation and tumor progression. Int J Biol Markers 2007; 22: 132-143. (Pubitemid 47062218)
-
(2007)
International Journal of Biological Markers
, vol.22
, Issue.2
, pp. 132-143
-
-
Shah, N.G.1
Trivedi, T.I.2
Tankshali, R.A.3
Goswami, J.A.4
Shah, J.S.5
Jetly, D.H.6
Kobawala, T.P.7
Patel, K.C.8
Shukla, S.N.9
Shah, P.M.10
Verma, R.J.11
-
16
-
-
0037096876
-
Constitutive activation of signal transducers and activators of transcription 3 correlates with cyclin D1 overexpression and may provide a novel prognostic marker in head and neck squamous cell carcinoma
-
Masuda M, Suzui M, Yasumatu R, et al. Constitutive activation of signal transducers and activators of transcription 3 correlates with cyclin D1 overexpression and may provide a novel prognostic marker in head and neck squamous cell carcinoma. Cancer Res 2002; 62: 3351-3355. (Pubitemid 34651376)
-
(2002)
Cancer Research
, vol.62
, Issue.12
, pp. 3351-3355
-
-
Masuda, M.1
Suzui, M.2
Yasumatu, R.3
Nakashima, T.4
Kuratomi, Y.5
Azuma, K.6
Tomita, K.7
Komiyama, S.8
Weinstein, I.B.9
-
17
-
-
33750496435
-
Stat3 expression in oral squamous cell carcinoma: Association with clinicopathological parameters and survival
-
Shah NG, Trivedi TI, Tankshali RA, et al. Stat3 expression in oral squamous cell carcinoma: association with clinicopathological parameters and survival. Int J Biol Markers 2006; 21: 175-183. (Pubitemid 44660290)
-
(2006)
International Journal of Biological Markers
, vol.21
, Issue.3
, pp. 175-183
-
-
Shah, N.G.1
Trivedi, T.I.2
Tankshali, R.A.3
Goswami, J.A.4
Jetly, D.H.5
Kobawala, T.P.6
Shukla, S.N.7
Shah, P.M.8
Verma, R.J.9
-
18
-
-
33749055594
-
Molecular cross-talk between the NFκB and STAT3 signaling pathways in head and neck squamous cell carcinoma
-
DOI 10.1593/neo.06274
-
Squarize CH, Castilho RM, Sriuranpong V, Pinto DS Jr, Gutkind JS,. Molecular cross-talk between the NFkappaB and STAT3 signaling pathways in head and neck squamous cell carcinoma. Neoplasia 2006; 8: 733-746. (Pubitemid 44465525)
-
(2006)
Neoplasia
, vol.8
, Issue.9
, pp. 733-746
-
-
Squarize, C.H.1
Castilho, R.M.2
Sriuranpong, V.3
Pinto Jr., D.S.4
Gutkind, J.S.5
-
19
-
-
0036569522
-
Activation of Stat-3 as one of the early events in tobacco chewing-mediated oral carcinogenesis
-
DOI 10.1002/cncr.10499
-
Nagpal JK, Mishra R, Das BR,. Activation of Stat-3 as one of the early events in tobacco chewing-mediated oral carcinogenesis. Cancer 2002; 94: 2393-2400. (Pubitemid 34457120)
-
(2002)
Cancer
, vol.94
, Issue.9
, pp. 2393-2400
-
-
Nagpal, J.K.1
Mishra, R.2
Das, B.R.3
-
20
-
-
16544373271
-
Constitutive activation of Stat3 correlates with increased expression of the c-Met/HGF receptor in oral squamous cell carcinoma
-
Klosek SK, Nakashiro K, Hara S, Li C, Shintani S, Hamakawa H,. Constitutive activation of Stat3 correlates with increased expression of the c-Met/HGF receptor in oral squamous cell carcinoma. Oncol Rep 2004; 12: 293-296.
-
(2004)
Oncol Rep
, vol.12
, pp. 293-296
-
-
Klosek, S.K.1
Nakashiro, K.2
Hara, S.3
Li, C.4
Shintani, S.5
Hamakawa, H.6
-
21
-
-
53349153184
-
Prognostic value of signal transducers and activators of transcription 3 in breast cancer
-
Sheen-Chen SM, Huang CC, Tang RP, Chou FF, Eng HL,. Prognostic value of signal transducers and activators of transcription 3 in breast cancer. Cancer Epidemiol Biomarkers Prev 2008; 17: 2286-2290.
-
(2008)
Cancer Epidemiol Biomarkers Prev
, vol.17
, pp. 2286-2290
-
-
Sheen-Chen, S.M.1
Huang, C.C.2
Tang, R.P.3
Chou, F.F.4
Eng, H.L.5
-
22
-
-
33847409232
-
Activation state egfr and STAT-3 as prognostic markers in resected non-small cell lung cancer
-
DOI 10.1016/j.lungcan.2006.11.003, PII S0169500206006040
-
Cortas T, Eisenberg R, Fu P, Kern J, Patrick L, Dowlati A,. Activation state EGFR and STAT-3 as prognostic markers in resected non-small cell lung cancer. Lung Cancer 2007; 55: 349-355. (Pubitemid 46343578)
-
(2007)
Lung Cancer
, vol.55
, Issue.3
, pp. 349-355
-
-
Cortas, T.1
Eisenberg, R.2
Fu, P.3
Kern, J.4
Patrick, L.5
Dowlati, A.6
-
23
-
-
0033805783
-
Molecular prognostic markers in pancreatic cancer
-
Coppola D,. Molecular prognostic markers in pancreatic cancer. Cancer Control 2000; 7: 421-427.
-
(2000)
Cancer Control
, vol.7
, pp. 421-427
-
-
Coppola, D.1
-
24
-
-
34247499895
-
Expression of NF-κB parallels COX-2 expression in oral precancer and cancer: Association with smokeless tobacco
-
DOI 10.1002/ijc.22657
-
Sawhney M, Rohatgi N, Kaur J, et al. Expression of NF-kappaB parallels COX-2 expression in oral precancer and cancer: association with smokeless tobacco. Int J Cancer 2007; 120: 2545-2556. (Pubitemid 46651274)
-
(2007)
International Journal of Cancer
, vol.120
, Issue.12
, pp. 2545-2556
-
-
Sawhney, M.1
Rohatgi, N.2
Kaur, J.3
Shishodia, S.4
Sethi, G.5
Gupta, S.D.6
Deo, S.V.S.7
Shukla, N.K.8
Aggarwal, B.B.9
Ralhan, R.10
-
25
-
-
0033529704
-
Stat3 as an oncogene
-
DOI 10.1016/S0092-8674(00)81959-5
-
Bromberg JF, Wrzeszczynska MH, Devgan G, et al. Stat3 as an oncogene. Cell 1999; 98: 295-303. (Pubitemid 29380565)
-
(1999)
Cell
, vol.98
, Issue.3
, pp. 295-303
-
-
Bromberg, J.F.1
Wrzeszczynska, M.H.2
Devgan, G.3
Zhao, Y.4
Pestell, R.G.5
Albanese, C.6
Darnell Jr., J.E.7
-
26
-
-
34247600538
-
STAT3 as a central mediator of neoplastic cellular transformation
-
DOI 10.1016/j.canlet.2006.10.017, PII S0304383506005763
-
Frank DA,. STAT3 as a central mediator of neoplastic cellular transformation. Cancer Lett 2007; 251: 199-210. (Pubitemid 46680370)
-
(2007)
Cancer Letters
, vol.251
, Issue.2
, pp. 199-210
-
-
Frank, D.A.1
-
27
-
-
47849132516
-
Rapid activation of Stat3 and ERK1/2 by nicotine modulates cell proliferation in human bladder cancer cells
-
Chen RJ, Ho YS, Guo HR, Wang YJ,. Rapid activation of Stat3 and ERK1/2 by nicotine modulates cell proliferation in human bladder cancer cells. Toxicol Sci 2008; 104: 283-293.
-
(2008)
Toxicol Sci
, vol.104
, pp. 283-293
-
-
Chen, R.J.1
Ho, Y.S.2
Guo, H.R.3
Wang, Y.J.4
-
28
-
-
33750135226
-
Receptor-mediated tobacco toxicity: Cooperation of the Ras/Raf-1/MEK1/ERK and JAK-2/STAT-3 pathways downstream of α7 nicotinic receptor in oral keratinocytes
-
DOI 10.1096/fj.06-6191com
-
Arredondo J, Chernyavsky AI, Jolkovsky DL, Pinkerton KE, Grando SA,. Receptor-mediated tobacco toxicity: cooperation of the Ras/Raf-1/MEK1/ERK and JAK- 2/STAT-3 pathways downstream of alpha7 nicotinic receptor in oral keratinocytes. FASEB J 2006; 20: 2093-2101. (Pubitemid 44953908)
-
(2006)
FASEB Journal
, vol.20
, Issue.12
, pp. 2093-2101
-
-
Arredondo, J.1
Chernyavsky, A.I.2
Jolkovsky, D.L.3
Pinkerton, K.E.4
Grando, S.A.5
-
29
-
-
34247281958
-
Signal transducer and activator of transcription 3 activation promotes invasive growth of colon carcinomas through matrix metalloproteinase induction 1
-
Svetlana A, Tsareva Y, Morigglz R, et al. Signal transducer and activator of transcription 3 activation promotes invasive growth of colon carcinomas through matrix metalloproteinase induction 1. Neoplasia 2007; 279: 279-291.
-
(2007)
Neoplasia
, vol.279
, pp. 279-291
-
-
Svetlana, A.1
Tsareva, Y.2
Morigglz, R.3
-
30
-
-
70249099280
-
Hypoxia induces chemoresistance in ovarian cancer cells by activation of signal transducer and activator of transcription 3
-
Selvendiran K, Bratasz A, Kuppusamy ML, Tazi MF, Rivera BK, Kuppusamy P,. Hypoxia induces chemoresistance in ovarian cancer cells by activation of signal transducer and activator of transcription 3. Int J Cancer 2009; 125: 2198-2204.
-
(2009)
Int J Cancer
, vol.125
, pp. 2198-2204
-
-
Selvendiran, K.1
Bratasz, A.2
Kuppusamy, M.L.3
Tazi, M.F.4
Rivera, B.K.5
Kuppusamy, P.6
-
31
-
-
0035136846
-
Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression
-
Epling-Burnette PK, Liu JH, Catlett-Falcone R, et al. Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression. J Clin Invest 2001; 107: 351-362.
-
(2001)
J Clin Invest
, vol.107
, pp. 351-362
-
-
Epling-Burnette, P.K.1
Liu, J.H.2
Catlett-Falcone, R.3
-
32
-
-
35348893870
-
Targeting the cytoplasmic and nuclear functions of signal transducers and activators of transcription 3 for cancer therapy
-
DOI 10.1158/1078-0432.CCR-06-2491
-
Germain D, Frank DA,. Targeting the cytoplasmic and nuclear functions of signal transducers and activators of transcription 3 for cancer therapy. Clin Cancer Res 2007; 13: 5665-5669. (Pubitemid 47583890)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.19
, pp. 5665-5669
-
-
Germain, D.1
Frank, D.A.2
-
33
-
-
0037386568
-
Targeted inhibition of Stat3 with a decoy oligonucleotide abrogates head and neck cancer cell growth
-
DOI 10.1073/pnas.0534764100
-
Leong PL, Andrews GA, Johnson DE, et al. Targeted inhibition of Stat3 with a decoy oligonucleotide abrogates head and neck cancer cell growth. Proc Natl Acad Sci U S A 2003; 100: 4138-4143. (Pubitemid 36418170)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.7
, pp. 4138-4143
-
-
Leong, P.L.1
Andrews, G.A.2
Johnson, D.E.3
Dyer, K.F.4
Xi, S.5
Mai, J.C.6
Robbins, P.D.7
Gadiparthi, S.8
Burke, N.A.9
Watkins, S.F.10
Grandis, J.R.11
-
34
-
-
55249102690
-
Stat3 as a molecular target in RNA interference-based treatment of oral squamous cell carcinoma
-
Klosek SK, Nakashiro K, Hara S, Goda H, Hamakawa H,. Stat3 as a molecular target in RNA interference-based treatment of oral squamous cell carcinoma. Oncol Rep 2008; 20: 873-878.
-
(2008)
Oncol Rep
, vol.20
, pp. 873-878
-
-
Klosek, S.K.1
Nakashiro, K.2
Hara, S.3
Goda, H.4
Hamakawa, H.5
-
35
-
-
33747470228
-
Targeting constitutive and interleukin-6-inducible signal transducers and activators of transcription 3 pathway in head and neck squamous cell carcinoma cells by curcumin (diferuloylmethane)
-
DOI 10.1002/ijc.21967
-
Chakravarti N, Myers JN, Aggarwal BB,. Targeting constitutive and interleukin-6-inducible signal transducers and activators of transcription 3 pathway in head and neck squamous cell carcinoma cells by curcumin (diferuloylmethane). Int J Cancer 2006; 119: 1268-1275. (Pubitemid 44258799)
-
(2006)
International Journal of Cancer
, vol.119
, Issue.6
, pp. 1268-1275
-
-
Chakravarti, N.1
Myers, J.N.2
Aggarwal, B.B.3
-
36
-
-
70849126744
-
Guggulsterone enhances head and neck cancer therapies via inhibition of signal transducer and activator of transcription-3
-
Leeman-Neill RJ, Wheeler SE, Singh SV, et al. Guggulsterone enhances head and neck cancer therapies via inhibition of signal transducer and activator of transcription-3. Carcinogenesis 2009; 30: 1848-1856.
-
(2009)
Carcinogenesis
, vol.30
, pp. 1848-1856
-
-
Leeman-Neill, R.J.1
Wheeler, S.E.2
Singh, S.V.3
-
37
-
-
59249093262
-
Guggulsterone inhibits angiogenesis by blocking STAT3 and VEGF expression in colon cancer cells
-
Kim ES, Hong SY, Lee HK, et al. Guggulsterone inhibits angiogenesis by blocking STAT3 and VEGF expression in colon cancer cells. Oncol Rep 2008; 20: 1321-1327.
-
(2008)
Oncol Rep
, vol.20
, pp. 1321-1327
-
-
Kim, E.S.1
Hong, S.Y.2
Lee, H.K.3
-
38
-
-
49249128130
-
Guggulsterone, a farnesoid X receptor antagonist, inhibits constitutive and inducible STAT3 activation through induction of a protein tyrosine phosphatase SHP-1
-
Ahn KS, Sethi G, Sung B, Goel A, Ralhan R, Aggarwal BB,. Guggulsterone, a farnesoid X receptor antagonist, inhibits constitutive and inducible STAT3 activation through induction of a protein tyrosine phosphatase SHP-1. Cancer Res 2008; 68: 4406-4415.
-
(2008)
Cancer Res
, vol.68
, pp. 4406-4415
-
-
Ahn, K.S.1
Sethi, G.2
Sung, B.3
Goel, A.4
Ralhan, R.5
Aggarwal, B.B.6
|