Ht31, a protein kinase A anchoring inhibitor, induces robust cholesterol efflux and reverses macrophage foam cell formation through ATP-binding cassette transporter A1

Journal of Biological Chemistry

Volumn 286, Issue 5, 2011, Pages 3370-3378

  Ma, Loretta ^b   Dong, Fumin ^a   Denis, Maxime ^a   Feng, Ying ^a   Wang, Ming Dong ^c   Zha, Xiaohui ^a,b  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

^c UNIVERSITY OF OTTAWA HEART INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ATHEROSCLEROTIC LESIONS; ATP-BINDING CASSETTE TRANSPORTERS; CELL TYPES; CELLULAR CHOLESTEROL; CHOLESTEROL EFFLUX; FOAM CELLS; INFLAMMATORY RESPONSE; LIVE CELL; PROTEIN KINASE A; THERAPEUTIC STRATEGY;

BIOSENSORS; CELLULAR MANUFACTURING; CYTOLOGY; ENZYMES; MACROPHAGES;

CHOLESTEROL;

ABC TRANSPORTER A1; APOLIPOPROTEIN A1; CYCLIC AMP DEPENDENT PROTEIN KINASE; HT31 PROTEIN; UNCLASSIFIED DRUG; ABC TRANSPORTER; CHOLESTEROL; HT 31 PROTEIN, SYNTHETIC; PROTEIN;

ANIMAL CELL; ARTICLE; CELL DAMAGE; CELL VIABILITY; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVITY; FOAM CELL; MACROPHAGE; MOUSE; NONHUMAN; PHOSPHOLIPID TRANSFER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; ANIMAL; CELL LINE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; PHYSIOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; CELL LINE; CHOLESTEROL; CYCLIC AMP-DEPENDENT PROTEIN KINASES; FOAM CELLS; MACROPHAGES; MICE; PROTEINS;

EID: 79952785951     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.173666     Document Type: Article

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