An adhesion protein of Salmonella enterica serovar Typhi is required for pathogenesis and potential target for vaccine development

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 8, 2011, Pages 3348-3353

  Ghosh, Shubhamoy ^a   Chakraborty, Krishnendu ^a   Nagaraja, Theeya ^a   Basak, Surajit ^a   Koley, Hemanta ^a   Dutta, Shanta ^a   Mitra, Utpala ^a   Das, Santasabuj ^a  

^a NATIONAL INSTITUTE OF CHOLERA AND ENTERIC DISEASES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; BACTERIAL VACCINE; IMMUNOGLOBULIN G; IRON; LAMININ; OUTER MEMBRANE PROTEIN; T2544 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERICIDAL ACTIVITY; BACTERIOLYSIS; BACTERIUM ADHERENCE; BACTERIUM ISOLATE; BINDING AFFINITY; BIOINFORMATICS; CONTROLLED STUDY; DRUG TARGETING; IMMUNITY; IN VITRO STUDY; IRON OVERLOAD; LD 50; MOUSE; MUTANT; NONHUMAN; PATHOGENESIS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN TARGETING; SALMONELLA; SALMONELLA ENTERICA TYPHI; SEROCONVERSION; SEROTYPE;

ANIMALS; ANTIBODY FORMATION; BACTERIAL ADHESION; BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL PROTEINS; BACTERIAL VACCINES; HUMANS; IMMUNIZATION; IMMUNOGLOBULIN G; MICE; SALMONELLA TYPHI; TREATMENT OUTCOME;

BACTERIA (MICROORGANISMS); MUS; SALMONELLA; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHI; SALMONELLA TYPHI;

EID: 79952756903     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1016180108     Document Type: Article

References (45)

1. Crump JA, Luby SP, Mintz ED (2004) The global burden of typhoid fever. Bull World Health Organ 82:346-353.
2. Monack DM, Mueller A, Falkow S (2004) Persistent bacterial infections: The interface of the pathogen and the host immune system. Nat Rev Microbiol 2: 747-765.
3. Crump JA, Mintz ED (2010) Global trends in typhoid and paratyphoid Fever. Clin Infect Dis 50:241-246.
4. Maskey AP, et al. (2006) Salmonella enterica serovar Paratyphi A and S. enterica serovar Typhi cause indistinguishable clinical syndromes in Kathmandu, Nepal. Clin Infect Dis 42:1247-1253.
5. Vernikos GS, Parkhill J (2006) Interpolated variable order motifs for identification of horizontally acquired DNA: Revisiting the Salmonella pathogenicity islands. Bioinformatics 22:2196-2203.
6. Cui C, et al. (2010) Physical and chemical characterization and immunologic properties of Salmonella enterica serovar typhi capsular polysaccharide-diphtheria toxoid conjugates. Clin Vaccine Immunol 17:73-79.
7. Fraser A, Paul M, Goldberg E, Acosta CJ, Leibovici L (2007) Typhoid fever vaccines: systematic review and meta-analysis of randomised controlled trials. Vaccine 25: 7848-7857.
8. Guzman CA, et al. (2006) Vaccines against typhoid fever. Vaccine 24:3804-3811.
9. Mai NL, et al. (2003) Persistent efficacy of Vi conjugate vaccine against typhoid fever in young children. N Engl J Med 349:1390-1391.
10. Kline KA, Fälker S, Dahlberg S, Normark S, Henriques-Normark B (2009) Bacterial adhesins in host-microbe interactions. Cell Host Microbe 5:580-592.
11. Hoiczyk E, Roggenkamp A, Reichenbecher M, Lupas A, Heesemann J (2000) Structure and sequence analysis of Yersinia YadA and Moraxella UspAs reveal a novel class of adhesins. EMBO J 19:5989-5999.
12. Schéele S, et al. (2007) Laminin isoforms in development and disease. J Mol Med 85: 825-836.
13. Jones BD, Ghori N, Falkow S (1994) Salmonella typhimurium initiates murine infection by penetrating and destroying the specialized epithelial M cells of the Peyer's patches. J Exp Med 180:15-23.
14. Wizemann TM, Adamou JE, Langermann S (1999) Adhesins as targets for vaccine development. Emerg Infect Dis 5:395-403.
15. Bogaert D, Hermans PW, Adrian PV, Rümke HC, de Groot R (2004) Pneumococcal vaccines: an update on current strategies. Vaccine 22:2209-2220.
16. Vidor E, Plotkin SA (2008) Immunogenicity of a two-component (PT & FHA) acellular pertussis vaccine in various combinations. Hum Vaccin 4:328-340.
17. Tan TT, Forsgren A, Riesbeck K (2006) The respiratory pathogen moraxella catarrhalis binds to laminin via ubiquitous surface proteins A1 and A2. J Infect Dis 194:493-497.
18. Boedeker EC (2005) Vaccines for enterotoxigenic Escherichia coli: Current status. Curr Opin Gastroenterol 21:15-19.
19. Menzies BE (2003) The role of fibronectin binding proteins in the pathogenesis of Staphylococcus aureus infections. Curr Opin Infect Dis 16:225-229.
20. Chatterjee R, Chaudhuri K, Chaudhuri P (2008) On detection and assessment of statistical significance of genomic islands. BMC Genomics 9:150.
21. Kyte J, Doolittle RF (1982) A simple method for displaying the hydropathic character of a protein. J Mol Biol 157:105-132.
22. Freeman TC, Jr., Landry SJ, Wimley WC (2011) The prediction and characterization of YshA, an unknown outer-membrane protein from Salmonella typhimurium. Biochim Biophys Acta 1808:287-297.
23. Auerbuch V, Lenz LL, Portnoy DA (2001) Development of a competitive index assay to evaluate the virulence of Listeria monocytogenes actA mutants during primary and secondary infection of mice. Infect Immun 69:5953-5957.
24. Joyce AR, et al. (2006) Experimental and computational assessment of conditionally essential genes in Escherichia coli. J Bacteriol 188:8259-8271.
25. Pedraza C, et al. (2000) Monocytic cells synthesize, adhere to, and migrate on laminin- 8 (alpha 4 beta 1 gamma 1). J Immunol 165:5831-5838.
26. Sordat I, et al. (2000)Tumorcellbuddingandlaminin-5 expression in colorectal carcinoma can be modulated by the tissue micro-environment. Int J Cancer 88:708-717.
27. Shen L (2009) Functional morphology of the gastrointestinal tract. Curr Top Microbiol Immunol 337:1-35.
28. Bäumler AJ, Tsolis RM, Heffron F (1996) The lpf fimbrial operon mediates adhesion of Salmonella typhimurium to murine Peyer's patches. Proc Natl Acad Sci USA 93: 279-283.
29. Hughes DT, et al. Chemical sensing in mammalian host-bacterial commensal associations. Proc Natl Acad Sci USA 107:9831-9836.
30. Osborne SE, et al. (2009) Pathogenic adaptation of intracellular bacteria by rewiring a cis-regulatory input function. Proc Natl Acad Sci USA 106:3982-3987.
31. Jones RL, et al. (1977) Effects of iron chelators and iron overload on Salmonella infection. Nature 267:63-65.
32. O'Brien AD (1982) Innate resistance of mice to Salmonella typhi infection. Infect Immun 38:948-952.
33. Song J, et al. (2010) A mouse model for the human pathogen Salmonella typhi. Cell Host Microbe 8:369-376.
34. Carter PB, Collins FM (1977) Assessment of typhoid vaccines by using the intraperitoneal route of challenge. Infect Immun 17:555-560.
35. Jones MA, Hulme SD, Barrow PA, Wigley P (2007) The Salmonella pathogenicity island 1 and Salmonella pathogenicity island 2 type III secretion systems play a major role in pathogenesis of systemic disease and gastrointestinal tract colonization of Salmonella enterica serovar Typhimurium in the chicken. Avian Pathol 36:199-203.
36. Hale C, et al. (2006) Evaluation of a novel Vi conjugate vaccine in a murine model of salmonellosis. Vaccine 24:4312-4320.
37. Holdsworth SR, Kitching AR, Tipping PG (1999) Th1 and Th2 T helper cell subsets affect patterns of injury and outcomes in glomerulonephritis. Kidney Int 55: 1198-1216.
38. Holmgren J, Czerkinsky C (2005) Mucosal immunity and vaccines. Nat Med 11(4 suppl): S45-S53.
39. Ofek I, Hasty DL, Sharon N (2003) Anti-adhesion therapy of bacterial diseases: prospects and problems. FEMS Immunol Med Microbiol 38:181-191.
40. Lin H, Lin Z, Meng C, Huang J, Guo Y (2010) Preparation and immunogenicity of capsular polysaccharide-surface adhesin A (PsaA) conjugate of Streptococcuspneumoniae. Immunobiology 215:545-550.
41. Ramakrishna C, et al. (2003) T helper responses to Japanese encephalitis virus infection are dependent on the route of inoculation and the strain of mouse used. J Gen Virol 84:1559-1567.
42. Esposito VM, Feeley JC, Leeder WD, Pittman M (1969) Immunological response of three mouse strains to typhoid vaccine and Vi antigen. J Bacteriol 99:8-12.
43. Barrett TJ, et al. (1983) Enzyme-linked immunosorbent assay for detection of human antibodies to Salmonella typhi Vi antigen. J Clin Microbiol 17:625-627.
44. MacLennan CA, et al. (2010) Dysregulated humoral immunity to nontyphoidal Salmonella in HIV-infected African adults. Science 328:508-512.
45. Parkhill J, et al. (2001) Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18. Nature 413:848-852.