Pathogenic adaptation of intracellular bacteria by rewiring a cis-regulatory input function

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 10, 2009, Pages 3982-3987

  Osborne, Suzanne E ^a   Walthers, Don ^b   Tomljenovic, Ana M ^a   Mulder, David T ^a   Silphaduang, Uma ^a   Duong, Nancy ^a   Lowden, Michael J ^c   Wickham, Mark E ^d   Waller, Ross F ^e   Kenney, Linda J ^b   Coombes, Brian K ^a,f  

^a MCMASTER UNIVERSITY   (Canada)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c Dartmouth College   (United States)

^d PHILIPS RESEARCH LABORATORIES   (Germany)

^e UNIVERSITY OF MELBOURNE   (Australia)

^f PUBLIC HEALTH AGENCY OF CANADA   (Canada)

Author keywords

Bacterial pathogenesis; cis regulatory mutation; Evo devo; Pathoadaptation; Regulatory evolution

Indexed keywords

REGULATOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL GENE; BACTERIAL VIRULENCE; BINDING SITE; CONTROLLED STUDY; EVOLUTIONARY ADAPTATION; GENE CONTROL; GENE MAPPING; GENE MUTATION; GENE SEQUENCE; GENETIC CODE; GENETIC TRANSCRIPTION; HORIZONTAL GENE TRANSFER; INTRACELLULAR BACTERIUM; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SALMONELLA; SRFN GENE; SSRB GENE; STRAIN DIFFERENCE;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; BACTERIAL PROTEINS; BASE SEQUENCE; GENE EXPRESSION REGULATION, BACTERIAL; GENES, BACTERIAL; HOST-PATHOGEN INTERACTIONS; INTRACELLULAR SPACE; MICE; MOLECULAR SEQUENCE DATA; MUTATION; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; REGULATORY SEQUENCES, NUCLEIC ACID; SALMONELLA; TRANSCRIPTION FACTORS; TYPHOID FEVER;

ANIMALIA; BACTERIA (MICROORGANISMS); MURINAE; SALMONELLA; SALMONELLA TYPHIMURIUM;

EID: 61849134259     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0811669106     Document Type: Article

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