Adhesins as targets for vaccine development

Emerging Infectious Diseases

Volumn 5, Issue 3, 1999, Pages 395-403

  Wizemann, Theresa M ^a   Adamou, John E ^a   Langermann, Solomon ^a  

^a MEDIMMUNE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; CELL RECEPTOR; VACCINE;

BACTERIAL COLONIZATION; BACTERIAL INFECTION; BACTERIUM ADHERENCE; DENTAL CARIES; DRUG IDENTIFICATION; DRUG ISOLATION; OTITIS MEDIA; PNEUMONIA; PROPHYLAXIS; REVIEW; SEPSIS; VACCINATION;

EID: 0033066669     PISSN: 10806040     EISSN: None     Source Type: Journal    
DOI: 10.3201/eid0503.990310     Document Type: Review

References (66)

1. Hilleman MR. Paper presented at the International Symposium on Recombinant Vectors in Vaccine Development; 1993 May 23; Albany, New York. [Nucleic Acids Technologies Foundation, sponsored by IABS, FDA, USDA/APHIS, and NIAID/NIH].
2. Alexander J, Fikes J, Hoffman S, Franke E, Sacci J, Appella E, Chisari, FV, et al. The optimization of helper T lymphocyte (HTL) function in vaccine development. Immunol Res 1998;18:79-92
3. St Geme JW III. Bacterial adhesins: determinants of microbial colonization and pathogenicity. Adv Pediatr 1997;44:43-72.
4. McGhee J, Mestecky J, Dertzbaugh MT, Eldridge JH, Hirasawa M, Kiyono H. The mucosal immune system: from fundamental concepts to vaccine development. Vaccine 1992;10.75-88
5. Langermann S. New approaches to mucosal immunization. Semin Gastrointest Dis 1996;7:12-8.
6. O'Hagan DT. Recent advances in vaccine adjuvants for systemic and mucosal administration. J Pharm Pharmacol 1998;50:1-10.
7. Mestecky J, Michalek SM, Moldoveanu Z, Russell MW. Routes of immunization and antigen delivery systems for optimal mucosal immune responses in humans. Behring Inst Mitt 1997;98:33-43.
8. Beachey EH. Bacterial adherence: adhesin-receptor interactions mediating the attachment of bacteria to mucosal surface. J Infect Dis 1981;143:325-45.
9. Beachey EH, Giampapa CS, Abraham SN. Bacterial adherence: adhesin receptor-mediated attachment of pathogenic bacteria to mucosal surfaces. American Review of Respiratory Diseases 1988;138.S45-8.
10. Ofek I, Sharon N. Adhesins as lectins: specificity and role in infection. Curr Top Microbiol Immunol 1990;151:91-113
11. Hultgren SJ, Abraham S, Capron M, Falk P, St. Geme JW, Normark S. Pilus and non-pilus bacterial adhesins: assembly and function in cell recognition. Cell 1993;73:887-901.
12. Jenkinson HF, Lamont RJ. Streptococcal adhesion and colonization. Crit Rev Oral Biol Med 1997;8:175-200.
13. Abraham SN, Sun D, Dale JB, Beachey EH. Conservation of the D-mannose-adhesion protein among type 1 fimbriated members of the family Enterobacteriacaea. Nature 1988;682-4.
14. Sokurenko EV, Courtney HS, Ohman DE, Klemm P, Hasty DL. FimH family of type 1 fimbrial adhesins: functional heterogeneity due to minor sequence variations among fimH genes. J Bacteriol 1994;176:748-55.
15. Langermann S, Palaszynski S, Barnhart M, Auguste G, Pinkner JS, Burlein J, et al. Prevention of mucosal Escherichia coli infection by FimH-based systemic vaccination. Science 1997;276:607-11.
16. Palaszynski S, Pinkner J, Leath S, Barren P, Auguste CG, Burlein J, et al. Systemic immunization with conserved pilus-associated adhesins protects against mucosal infections. Dev Biol Stand 1998;92:117-22.
17. Finlay B, Falkow S. Common themes in microbial pathogenicity. Microbiological Review 1989;53:210-30.
18. Hoepelman AI, Tuomanen EI. Consequences of microbial attachment: directing host cell functions with adhesins Infect Immun 1992;60:1729-33.
19. Svanborg C, Hedlund M, Connell H, Agace W, Duane, RD, Nilsson A, et al. Bacterial adherence and mucosal cytokine responses. Receptors and transmembrane signaling. Ann NY Acad Sci 1996;797:177-90.
20. Falkow S. Invasion and intracellular sorting of bacteria: searching for bacterial genes expressed during host/ pathogen interactions. J Clin Invest 1997;100:239-43
21. Mecsas JJ, Strauss EJ. Molecular mechanisms of bacterial virulence: type III secretion and pathogenicity islands Emerg Infect Dis 1996;2.270-88.
22. Zhang JP, Normark S. Induction and gene expression in Escherichia coli after pilus-mediated adherence. Science 1996;273:1234-6.
23. Donnenberg MS, Kaper JB, Finlay BB. Interactions between enteropathogenic Escherichia coli and host epithelial cells. Trends Microbiol 1997;5:109-14.
24. Kenny B, DeVinney R, Stein M, Reinscheid DJ, Frey EA, Finlay BB. Enteropathogenic E. coli (EPEC) transfers its receptor for intimate adherence into mammalian cells. Cell 1997;91:511-20.
25. Svanborg-Eden C, Marild S, Korhonen TK Adhesion inhibition by antibodies. Scand J Infect Dis 1982;33.72-8.
26. O'Hanley P, Lark D, Falkow S, Schoolnik G. Molecular basis of Escherichia coli colonization of the upper urinary tract in Balb/c mice. Gal-Gal pill immunization prevents Escherichia coli pyelonephritis in the Balb/c mouse model of human pyelonephritis. J Clin Invest 1985;75:347-60.
27. Pecha B, Low D, O'Hanley P. Gal-Gal pili vaccines prevent pyelonephritis by piliated Escherichia coli in a murine model. Single component Gal-Gal pili vaccines prevent pyelonephritis by homologous and heterologous piliated E. coli strains. J Clin Invest 1989;83:2102-8.
28. Moon HW, Bunn TO. Vaccines for preventing enterotoxigenic Escherichia coli infections in farm animals. Vaccine 1993;11:213-20.
29. Maurer L, Orndorff P. Identification and characterization of genes determining receptor binding and pilus length of Escherichia coli type 1 pili. J Bacteriol 1987;169.640-5.
30. Hanson MS, Brinton CC Jr. Identification and characterization of the Escherichia coli type 1 pilus adhesin protein. Nature 1988;322:265-8.
31. Bock K, Breimer ME, Brignole A, Hansson GC, Karlsson KA, Larson, G, et al. Specificity of binding of a strain of uropathogenic Escherichia coli to Gal 1-4Gal-containing glycosphingolipids. J Biol Chem 1985;260:8545-51.
32. Stromberg N, Marklund BI, Lund B, Ilver D, Hamers A, Gaastra W, et al. Host-specificity of uropathogenic Escherichia coli depends on differences in binding specificity to Gal 1-4Gal-contaming isoreceptors. EMBO J 1990;9:2001-10.
33. Hultgren SJ, Jones CH. Utility of the immunoglobulin-like fold of chaperones in shaping organelles of attachment in pathogenic bacteria. American Society for Microbiology News 1195;61:457-64.
34. Brennan MJ, Shahin RD. Pertussis antigens that abrogate bacterial adherence and elicit immunity. Am J Respir Crit Care Med 1996;154:S145-9.
35. St. Geme JW III. Progress towards a vaccine for nontypable Haemophilus influenzae. The Finnish Medical Society DUODECIM. Ann Med 1996;28:31-7.
36. Barenkamp SJ, St Geme JW III. Identification of a second family of high-molecular-weight adhesion proteins expressed by non-typable Haemophilus influenzae. Mol Microbiol 1996;19:1215-23.
37. Ilver D, Arnqvist A, Ogren J, Frick IM, Kersulyte D, Incecik ET, et al. Helicobacter pylori adhesin binding fucosylated histo-blood group antigens revealed by retagging. Science 1998;279:373-7.
38. Roberts JA. Tropism in bacterial infections: urinary tract infections. J Urol 1996;156:1552-9.
39. Demuth DR, Duan Y, Brooks W, Holmes AR, McNab R, Jenkinson HF. Tandem genes encode cell-surface polypeptides SspA and SspB which mediate adhesion of the oral bacterium Streptococcus gordonii to human and bacterial receptors. Mol Microbiol 1996;20:403-13.
40. McNab R, Jenkinson HF, Loach DM, Tannock GW. Cell-surface-associated polypeptides CshA and CshB of high molecular mass are colonization determinants in the oral bacterium Streptococcus gordonii. Mol Microbiol 1994;14:743-5
41. Jonsson K, Signas C, Muller HP, Lindberg M. Two different genes encode fibronectin binding proteins in Staphylococcus aureus. The complete nucleotide sequence and characterization of the second gene. Eur J Biochem 1991;202:1041-8.
42. Talay SR, Valentin-Weigand P, Timmis KN, Chhatwal GS. Domain structure and conserved epitopes of Sfb protein, the fibronectin-binding protein adhesin of Streptococcus pyogenes. Mol Microbiol 1994;13:531-9.
43. Hanski E, Caparon M Protein F, a fibronectin-binding protein, is an adhesin of the group A streptococcus Streptococcus pyogenes. Proc Natl Acad Sci U S A 1992;89.6172-6.
44. Burnette-Curley D, Wells V, Viscount H, Munro CL, Fenno JC, Fives-Taylor P, et al. FimA, a major virulence factor associated with Streptococcus parasanguis endocarditis. Infect Immun 1995;63:4669-74.
45. Rosenow C, Ryan P, Weiser JN, Johnson S, Fontan P, Ortqvist A, et al. Contribution of novel choline-binding proteins to adherence, colonization and immunogenicity of Streptococcus pneumoniae. Mol Microbiol 1997;25:819-29
46. Hammerschmidt S, Talay SR, Brandtzaeg P, Chhatwal GS. SpsA, a novel pneumococcal surface protein with specific binding to secretory immunoglobulin A and secretory component. Mol Microbiol 1997;25:1113-24
47. Briles DE, Hollingshead SK, Swiatlo E, Brooks-Walter A, Szalai A, Virolainen A, et al. PspA and PspC: their potential for use as pneumococcal vaccines. Microb Drug Resist 1997;3:401-8.
48. Smith BL, Cheng Q, Hostetter MK. Characterization of a pneumococcal surface protein that binds complement protein C3 and its role in adhesion [poster D-122]. The American Society for Microbiology (1998) 98th General Meeting; Atlanta, Georgia.
49. Hajishengallis G, Russell MW, Michalek SM. Comparison of an adherence domain and a structural region of Streptococcus mutans antigen I/II in protective immunity against dental caries in rats after intranasal immunization Infect Immun 1998;66:1740-3.
50. Crowley PJ, Brady LJ, Piacentini DA, Bleiweis AS Identification of a salivary agglutinin-binding domain within cell surface adhesin P1 of Streptococcus mutans Infect Immun 1993;61:1547-52.
51. Todryk SM, Kelly CG, Lehner T. Effect of route of immunisation and adjuvant on T and B cell epitope recognition within a streptococcal antigen. Vaccine 1998;16:174-80.
52. McNab R, Holmes AR, Clark JM, Tannock GW, Jenkinson HF. Cell surface polypeptide CshA mediates binding of Streptococcus gordonii to other oral bacteria and to immobilized fibronectin. Infect Immun 1996;64:4202-10.
53. Schennings T, Heimdahl A, Coster K, Flock J-I. Immunization with fibronectin binding protein from Staphylococcus aureus protects against experimental endocarditis in rats. Microb Pathog 1993;15:227-36.
54. Lee JC. The prospects for developing a vaccine against Staphylococcus aureus. Trends Microbiol 1996;4:162-6.
55. Molinari G, Talay SR, Valentin-Weigand P, Rohde M, Chhatwal GS. The fibronectin-binding protein of Streptococcus pyogenes, SfbI, is involved in the internalization of group A streptococci by epithelial cells. Infect Immun 1997;65:1357-63.
56. Correia FF, DiRienzo JM, McKay TL, Rosan B. scbA from Streptococcus crista CC5A: an atypical member of the lrαI gene family. Infect Immun 1996;64:2114-21.
57. Dintilhac A, Alloing G, Granadel C, Claverys JP. Competence and virulence of Streptococcus pneumoniae: Adc and PsaA mutants exhibit a requirement for Zn and Mn resulting from inactivation of putative ABC metal permeases. Mol Microbiol 1997;25:727-39.
58. Fenno JC, Shaikh A, Spatafora G, Fives-Taylor P. The fimA locus of Streptococcus parasanguis encodes an ATP-binding membrane transport system. Mol Microbiol 1995;15:849-63.
59. Talkington DF, Brown BG, Tharpe JA, Koenig A, Russell H. Protection of mice against fatal pneumococcal challenge by immunization with pneumococcal surface adhesin A (PsaA). Microb Pathog 1996;21:17-22.
60. Berry AM, Paton JC. Sequence heterogenity of PsaA, a 37-kilodalton putative adhesin essential for virulence of Streptococcus pneumoniae. Infect Immun 1996;64:5255-62.
61. Novak R, Brown JS, Charpentier E, Tuamonen E. Penicillin tolerance genes of Streptococcus pneumoniae: the ABC-type manganese permease complex Psa. Mol Microbiol 1998;29:1285-96.
62. Dormizter M, Wizemann TM, Adamou JE, Walsh W, Gayle T, Langermann S, et al. Sequence and structural analysis of CbpA, a novel choline-binding protein of Streptococcus pneumoniae [poster B-3]. The American Society for Microbiology (1998) 98th General Meeting; Atlanta, Georgia.
63. Schaeffer AJ, Amundsen SK, Schnidt LN. Adherence of Escherichia coli to human urinary tract epithelial cells. Infect Immun 1979;24:753-9.
64. Ofek I, Mosek A, Sharon N. Mannose-specific adherence of Escherichia coli freshly excreted in the urine of patients with urinary tract infections, and of isolates subcultured from the infected urine. Infect Immun 1981;34:708-11.
65. Connell H, Agace W, Klemm P, Schembri M, Marild S, Svanborg C. Type 1 fimbrial expression enhances Escherichia coli virulence for the urinary tract. Proc Natl Acad Sci U S A 1996;93:9827-32.
66. Frey A, Neutra MR. Targeting of mucosal vaccines to Peyer's patch M cells. Behring Inst Mitt 1997;98:376-89.