Simultaneous single-molecule measurements of phage T7 replisome composition and function reveal the mechanism of polymerase exchange

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 9, 2011, Pages 3584-3589

  Loparo, Joseph J ^a   Kulczyk, Arkadiusz W ^a   Richardson, Charles C ^a   Van Oijen, Antoine M ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Bacteriophage T7; DNA replication; Flow stretching; Fluorescence

Indexed keywords

DNA POLYMERASE; HELICASE; REPLISOME;

ARTICLE; BACTERIOPHAGE T7; DNA REPLICATION; DNA SYNTHESIS; MOLECULE; PRIORITY JOURNAL; STOICHIOMETRY;

BACTERIOPHAGE T7; BIOCHEMISTRY; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; KINETICS; MULTIENZYME COMPLEXES; MUTANT PROTEINS; PROTEIN BINDING; SOLUTIONS; VIRAL PROTEINS;

EID: 79952746781     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1018824108     Document Type: Article

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