Macrophage migration inhibitory factor contributes to development of nonsteroidal anti-inflammatory drugs-induced gastric injury in mice

International Immunopharmacology

Volumn 11, Issue 4, 2011, Pages 418-423

  Ohkawara, Tatsuya ^a,b   Takeda, Hiroshi ^a   Ohnishi, Shunsuke ^a   Kato, Mototsugu ^a   Nishihira, Jun ^b   Asaka, Masahiro ^a  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b HOKKAIDO INFORMATION UNIVERSITY   (Japan)

Author keywords

Gastric injury; Macrophage migration inhibitory factor; Non steroidal anti inflammatory drugs

Indexed keywords

HEAT SHOCK PROTEIN 70; INDOMETACIN; MACROPHAGE MIGRATION INHIBITION FACTOR; NONSTEROID ANTIINFLAMMATORY AGENT; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; DISEASE SEVERITY; INFLAMMATORY INFILTRATE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STOMACH ACID SECRETION; STOMACH INJURY; UPREGULATION; WILD TYPE;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BLOTTING, WESTERN; ENZYME-LINKED IMMUNOSORBENT ASSAY; GASTRIC ACID; GASTRIC MUCOSA; GASTRITIS; INDOMETHACIN; INTRAMOLECULAR OXIDOREDUCTASES; MACROPHAGE MIGRATION-INHIBITORY FACTORS; MALE; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; TUMOR NECROSIS FACTOR-ALPHA;

EID: 79952737689     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2010.12.009     Document Type: Article

References (36)

1. Laine L. Approaches to nonsteroidal anti-in.ammatory drug use in the high-risk patient. Gastroenterology 2001;120:594-606. (Pubitemid 32171634)
2. Buttgereit F, Burmester GR, Simon LS. Gastrointestinal toxic side effects of nonsteroidal anti-inflammatory drugs and cyclooxygenase-2-specific inhibitors. Am J Med 2001;110:13S-9S.
3. Santucci L, Fiorucci S, Giansanti M, Brunori PM, Di Matteo FM, Morelli A. Pentoxifylline prevents indomethacin induced acute gastric mucosal damage in rats: role of tumour necrosis factor alpha. Gut 1994;35:909-15. (Pubitemid 24202720)
4. Santucci L, Fiorucci S, Di Matteo FM, Morelli A. Role of tumor necrosis factor alpha release and leukocyte margination in indomethacin-induced gastric injury in rats. Gastroenterology 1995;108:393-401.
5. Appleyard CB, McCafferty DM, Tigley AW, Swain MG, Wallace JL. Tumor necrosis factor mediation of NSAID-induced gastric damage: role of leukocyte adherence. Am J Physiol 1996;270:G42-8.
6. David JR. Delayed hypersensitivity in vitro: its mediation by cell-free substances formed by lymphoid cell-antigen interaction. Proc Natl Acad Sci USA 1966;56: 72-7.
7. Nishihira J. Novel pathophysiological aspects of macrophage migration inhibitory factor. Int J Mol Med 1998;2:17-28.
8. Mikulowska A, Metz CN, Bucala R, Holmdahl R. Macrophage migration inhibitory factor is involved in the pathogenesis of collagen type II-induced arthritis in mice. J Immunol 1997;158:5514-7. (Pubitemid 127681261)
9. de Jong YP, Abadia-Molina AC, Satoskar AR, Clarke K, Rietdijk ST, Faubion WA, et al. Development of chronic colitis is dependent on the cytokine MIF. Nat Immunol 2001;2:1061-6. (Pubitemid 33069502)
10. Leech M, Metz C, Bucala R, Morand EF. Regulation of macrophage migration inhibitory factor by endogenous glucocorticoids in rat adjuvant-induced arthritis. Arthritis Rheum 2000;43:827-33.
11. Ohkawara T, Nishihira J, Takeda H, Hige S, Kato M, Sugiyama T, et al. Amelioration of dextran sulfate sodium-induced colitis by anti-macrophage migration inhibitory factor antibody in mice. Gastroenterology 2002;123:256-70. (Pubitemid 34747546)
12. Xia HH, Lam SK, Huang XR, Wong WM, Leung SY, Yuen ST, et al. Helicobacter pylori infection is associated with increased expression of macrophage migratory inhibitory factor-by epithelial cells, T cells, and macrophages-in gastric mucosa. J Infect Dis 2004;190:293-302. (Pubitemid 38951969)
13. Huang XR, Chun Hui CW, Chen YX, Wong BC, Fung PC, Metz C, et al. Macrophage migration inhibitory factor is an important mediator in the pathogenesis of gastric inflammation in rats. Gastroenterology 2001;121:619-30. (Pubitemid 32822577)
14. Honma N, Koseki H, Akasaka T, Nakayama T, Taniguchi M, Serizawa I, et al. Deficiency of the macrophage migration inhibitory factor gene has no significant effect on endotoxaemia. Immunology 2000;100:84-90. (Pubitemid 30242886)
15. Beck PL, Xavier R, Lu N, Nanda NN, Dinauer M, Podolsky DK, et al. Mechanisms of NSAID-induced gastrointestinal injury defined using mutant mice. Gastroenterology 2000;119:699-705.
16. Farrell JJ, Taupin D, Koh TJ, Chen D, Zhao CM, Podolsky DK, et al. TFF2/SP-deficient mice show decreased gastric proliferation, increased acid secretion, and increased susceptibility to NSAID injury. J Clin Invest 2002;109:193-204. (Pubitemid 34083739)
17. Calandra T, Bernhagen J, Mitchell RA, Bucala R. The macrophage is an important and previously unrecognized source of macrophage migration inhibitory factor. J Exp Med 1994;179:1895-902. (Pubitemid 24155670)
18. Lan HY, Bacher M, Yang N, Mu W, Nikolic-Paterson DJ, Metz C, et al. The pathogenic role of macrophage migration inhibitory factor in immunologically induced kidney disease in the rat. J Exp Med 1997;185:1455-65. (Pubitemid 27187602)
19. Donnelly SC, Haslett C, Reid PT, Grant IS, Wallace WA, Metz CN, et al. Regulatory role for macrophage migration inhibitory factor in acute respiratory distress syndrome. Nat Med 1997;3:320-3. (Pubitemid 27112930)
20. Onodera S, Tanji H, Suzuki K, Kaneda K, Mizue Y, Sagawa A, et al. High expression of macrophage migration inhibitory factor in the synovial tissues of rheumatoid joints. Cytokine 1999;11:163-7. (Pubitemid 29116556)
21. Yeomans ND, Skeljo MV, Giraud AS. The role of acid regulation in the treatment of NSAID-induced mucosal damage. Digestion 1992;51(Suppl 1):3-10.
22. Leandro G, Pilotto A, Franceschi M, Bertin T, Lichino E, Di Mario F. Prevention of acute NSAID-related gastroduodenal damage: a meta-analysis of controlled clinical trials. Dig Dis Sci 2001;46:1924-36. (Pubitemid 32844159)
23. Ballabeni V, Calcina F, Bosetti M, Chiavarini M, Bertoni S, Impicciatore M, et al. Different role of the histamine H3-receptor in vagal-, betanechol-, pentagastrin-induced gastric acid secretion in anaesthetized rats. Scand J Gastroenterol 2002;37:754-8. (Pubitemid 34836809)
24. Appleyard CB, McCafferty DM, Tigley AW, Swain MG, Wallace JL. Tumor necrosis factor mediation of NSAID-induced gastric damage: role of leukocyte adherence. Am J Physiol 1996;270:G42-8.
25. Lan HY, Yang N, Nikolic-Paterson DJ, Yu XQ, Mu W, Isbel NM, et al. Expression of macrophage migration inhibitory factor in human glomerulonephritis. Kidney Int 2000;57:499-509. (Pubitemid 30430641)
26. Benjamin IJ, McMIllan DR. Stress (heat shock) proteins molecular chaperones. Circ Res 1998;83:117-32.
27. Rokutan K. Role of heat shock proteins in gastric mucosal protection. J Gastroenterol Hepatol 2000;15(Suppl):D12-9.
28. Shichijo K, Ihara M, Matsuu M, Ito M, Okumura Y, Sekine I. Overexpression of heat shock protein 70 in stomach of stress-induced gastric ulcer-resistant rats. Dig Dis Sci 2003;48:340-8. (Pubitemid 36233002)
29. Ebert MP, Schäfer C, Chen J, Hoffmann J, Gu P, Kubisch C, et al. Protective role of heat shock protein 27 in gastric mucosal injury. J Pathol 2005;207:177-84. (Pubitemid 41404148)
30. Ohkawara T, Nishihira J, Ishiguro Y, Otsubo E, Nagai K, Takeda H, et al. Resistance to experimental colitis depends on cytoprotective heat shock proteins in macrophage migration inhibitory factor null mice. Immunol Lett 2006;107: 148-54. (Pubitemid 44779819)
31. Bourdi M, Reilly TP, Elkahloun AG, George JW, Pohl LR. Macrophage migration inhibitory factor in drug-induced liver injury: a role in susceptibility and stress responsiveness. Biochem Biophys Res Commun 2002;294:225-30. (Pubitemid 34694081)
32. Calandra T, Bernhagen J, Metz CN, Spiegel LA, Bacher M, Donnelly T, et al. MIF as a glucocorticoid-induced modulator of cytokine production. Nature 1995;377: 68-71.
33. Bucala R. MIF rediscovered: pituitary hormone and glucocorticoid-induced regulator of cytokine production. FASEB J 1996;7:19-24. (Pubitemid 27202662)
34. Leng L, Metz CN, Fang Y, Xu J, Donnelly S, Baugh J, et al. MIF signal transduction initiated by binding to CD74. J Exp Med 2003;197:1467-76. (Pubitemid 36686708)
35. Schwartz V, Lue H, Kraemer S, Korbiel J, Krohn R, Ohl K, et al. A functional heteromeric MIF receptor formed by CD74 and CXCR4. FEBS Lett 2009;583: 2749-57.
36. Wong BL, Zhu SL, Huang XR, Ma J, Xia HH, Bucala R, et al. Essential role for macrophage migration inhibitory factor in gastritis induced by Helicobacter pylori. Am J Pathol 2009;174:1319-28.