Realgar and realgar-containing Liu-Shen-Wan are less acutely toxic than arsenite and arsenate

Journal of Ethnopharmacology

Volumn 134, Issue 1, 2011, Pages 26-31

  Liu, Jie ^a,c   Liang, Shi Xia ^a   Lu, Yuan Fu ^a,b   Miao, Jia Wei ^a   Wu, Qin ^a   Shi, Jing Shan ^a  

^a ZUNYI MEDICAL UNIVERSITY   (China)

^b SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^c UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

Acute toxicity; Arsenate; Arsenite; Realgar; Realgar containing Liu Shen Wan; Tissue As accumulation

Indexed keywords

ALANINE AMINOTRANSFERASE; ARSENIC ACID; ARSENIC TRIOXIDE; ASPARTATE AMINOTRANSFERASE; CHINESE DRUG; HEME OXYGENASE 1; METALLOTHIONEIN I; NITROGEN; REALGAR; REALGAR CONTAINING LIU SHEN WAN; UNCLASSIFIED DRUG; UREA;

ACUTE TOXICITY; ADULT ANIMAL; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; GENE EXPRESSION; HISTOPATHOLOGY; LIVER INJURY; MALE; MOUSE; NEPHROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; RISK ASSESSMENT; SINGLE DRUG DOSE; UREA NITROGEN BLOOD LEVEL;

ALANINE TRANSAMINASE; ANIMALS; ARSENATES; ARSENICALS; ARSENITES; COMPLEX MIXTURES; DOSE-RESPONSE RELATIONSHIP, DRUG; KIDNEY; LIVER; MEDICINE, CHINESE TRADITIONAL; MICE; SULFIDES;

ANIMALIA; MUS;

EID: 79952706390     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2010.11.052     Document Type: Article

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