Proanthocyanidin-enriched extract from Myrothamnus flabellifolia Welw. exerts antiviral activity against herpes simplex virus type 1 by inhibition of viral adsorption and penetration

Journal of Ethnopharmacology

Volumn 134, Issue 2, 2011, Pages 468-474

  Gescher, Kirsten ^a   Kühn, Joachim ^b   Lorentzen, Eva ^b   Hafezi, Wali ^b   Derksen, Andrea ^a   Deters, Alexandra ^a   Hensel, Andreas ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b UNIVERSITY HOSPITAL MÜNSTER   (Germany)

Author keywords

Antiviral; Attachment; gD protein; Herpes simplex virus type 1; Myrothamnaceae; Myrothamnus flabellifolia Welw.; Organotypic skin model; Penetration

Indexed keywords

ACETONE; ANTIVIRUS AGENT; GLYCOPROTEIN D; MYROTHAMNUS FLABELLIFOLIA EXTRACT; PLANT EXTRACT; POLYPHENOL; PROANTHOCYANIDIN; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN; WATER;

ADENOVIRUS; ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CHLOROCEBUS; CONTROLLED STUDY; CYTOTOXICITY TEST; DRUG MECHANISM; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; HUMAN TISSUE; IC 50; IMMUNOFLUORESCENCE; INOCULATION; KERATINOCYTE; KIDNEY CELL; LUNG FIBROBLAST; MEDICINAL PLANT; MYROTHAMNUS FLABELLIFOLIA; NONHUMAN; PHARMACOLOGICAL BLOCKING; PLANT LEAF; SOUTH AFRICA; VERO CELL; VIRAL SKIN DISEASE; VIRUS ATTACHMENT; VIRUS ENTRY; VIRUS INHIBITION; VIRUS PARTICLE; WESTERN BLOTTING;

ADENOVIRIDAE; ADENOVIRIDAE INFECTIONS; ANGIOSPERMS; ANIMALS; ANTIVIRAL AGENTS; CELL LINE; CERCOPITHECUS AETHIOPS; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; HUMANS; INHIBITORY CONCENTRATION 50; KERATINOCYTES; PHYTOTHERAPY; PLANT COMPONENTS, AERIAL; PLANT EXTRACTS; PROANTHOCYANIDINS; SKIN; VERO CELLS; VIRAL ENVELOPE PROTEINS; VIRUS INTEGRATION;

ADENOVIRIDAE; HUMAN ADENOVIRUS TYPE 3; HUMAN HERPESVIRUS 1; MYROTHAMNACEAE; MYROTHAMNUS FLABELLIFOLIUS; SELAGINELLA PILIFERA;

EID: 79952703921     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2010.12.038     Document Type: Article

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