An extract of Pelargonium sidoides (EPs 7630) inhibits in situ adhesion of Helicobacter pylori to human stomach

Phytomedicine

Volumn 14, Issue 4, 2007, Pages 285-288

  Wittschier, N ^a   Faller, G ^b   Hensel, A ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b St Vincentius Hospital   (Germany)

Author keywords

Adhesion; EPs 7630; Helicobacter pylori; Human stomach; Pelargonium sidoides

Indexed keywords

PELARGONIUM SIDOIDES EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ARTICLE; BACTERIUM ADHERENCE; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; FLUORESCENCE MICROSCOPY; HELICOBACTER PYLORI; HUMAN; HUMAN TISSUE; NONHUMAN; PELARGONIUM; PELARGONIUM SIDOIDES; PLANT ROOT; PRIORITY JOURNAL; RESPIRATORY TRACT INFECTION; STOMACH;

ANTI-BACTERIAL AGENTS; BACTERIAL ADHESION; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; MICROBIAL SENSITIVITY TESTS; PELARGONIUM; PHYTOTHERAPY; PLANT EXTRACTS; PLANT ROOTS; STOMACH;

BACTERIA (MICROORGANISMS); HELICOBACTER PYLORI; PELARGONIUM; PELARGONIUM SIDOIDES;

EID: 33847740239     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2006.12.008     Document Type: Article

References (11)

1. Dorfmüller A., Jung I., Tioua D.L., Engels I., Daschner F.D., and Frank U. Indirekte antibakterielle Wirkmechanismen des Pelargonium-sidoides-Wurzelextraktes EPs7630: Hemmung der Interaktion von A-Streptokokken und HEp-2-Zellen. Zt. Phytother. 26 Suppl. (2005) S6-S7
2. Falk P., Roth K.A., Borén T., Westblom T.U., Gordon J.I., and Normark S. An in vitro adherence assay reveals that Helicobacter pylori exhibits cell lineage specific tropism in the human gastric epithelium. Proc. Natl. Acad. Sci. USA 90 (1993) 2035-2039
3. Kayser O., and Kolodziej H. Antibacterial activity of extracts and constituents of Pelargonium sidoides and Pelargonium reniforme. Planta Med. 63 (1997) 508-510
4. Kayser O., Kolodziej H., and Kiderlen A.F. Immunmodulatory principles of Pelargonium sidoids. Phytother. Res. 15 (2001) 122-126
5. Koch E., Lanzendörfer-Goossen S.H., and Wohn C. Stimulation of interferon (INF)-β-synthesis and natural liller (NK) cell activity by an aqueous-ethanolic extract from roots of Pelargonium sidoides (Umckaloabo). Naunyn-Schmiedeberg's Arch. Pharmacol. 365 Suppl. 1 (2002) R75 (Abstr. 288)
6. Kolodziej H. Traditionally used Pelargonium species: chemistry and biological activity of Umckaloabo extracts and their constituents. Curr. Topics Phytochem. 3 (2000) 77-93
7. Kolodziej, H., Kayser, O., 1998. Pelargonium sidoides DC. Zt. Phytother. 19, 141-151.
8. Lengsfeld C., Deters A., Faller G., and Hensel A. High molecular weight polysaccharides from black currant seeds inhibit adhesion of Helicobacter pylori to human gastric mucosa. Planta Med. 70 (2004) 620-626
9. Lengsfeld C., Titgemeyer F., Faller G., and Hensel A. Glycosylated compounds from okra inhibit adhesion of Helicobacter pylori to human gastric mucosa. J. Agric. Food Chem. 52 (2004) 1495-1503
10. Odenbreit S. Adherence properties of Helicobacter pylori: impact on pathogenesis and adaption to the host. Int. J. Med. Microbiol. 295 (2005) 317-324
11. Seidel V., and Taylor P.W. In vitro activity of extracts and constituents of Pelargonium against rapidly growing mycobacteria. Int. J. Antimicrob. Agents 23 (2004) 613-619