Antiplatelet effects of Spatholobus suberectus via inhibition of the glycoprotein IIb/IIIa receptor

Journal of Ethnopharmacology

Volumn 134, Issue 2, 2011, Pages 460-467

  Lee, Beom Joon ^a   Jo, In Young ^a   Bu, Youngmin ^a   Park, Jae Woo ^a   Maeng, Sungho ^a   Kang, Hee ^a   Jang, Woochang ^a   Hwang, Deok Sang ^a   Lee, Wookyoung ^a   Min, Kyoungyoon ^a   Kim, Jong In ^a   Yoo, Hye Hyun ^b   Lew, Jae Hwan ^a  

^a Kyung Hee University   (South Korea)

^b Hanyang University   (South Korea)

Author keywords

Antiplatelet agent; Glycoprotein IIb IIIa; Platelet aggregation; Spatholobus suberectus; Thromboxane A2

Indexed keywords

ADENOSINE DIPHOSPHATE; ANTITHROMBOCYTIC AGENT; COLLAGEN; FIBRINOGEN RECEPTOR; HEPARIN; PLANT EXTRACT; SPATHOLOBUS SUBERECTUS EXTRACT; THROMBOXANE A2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; FEMALE; HEMOSTASIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MEDICINAL PLANT; MOUSE; NONHUMAN; PARTIAL THROMBOPLASTIN TIME; PLANT STEM; PROTHROMBIN TIME; SPATHOLOBUS SUBERECTUS; THROMBOCYTE AGGREGATION INHIBITION; THROMBOCYTE RICH PLASMA; THROMBOEMBOLISM;

ADENOSINE DIPHOSPHATE; ANIMALS; COLLAGEN; DOSE-RESPONSE RELATIONSHIP, DRUG; EPINEPHRINE; FABACEAE; FAR EAST; FEMALE; FIBRINOGEN; HUMANS; MICE; MICE, INBRED ICR; PHYTOTHERAPY; PLANT EXTRACTS; PLANT STEMS; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PLATELET-RICH PLASMA; THROMBOEMBOLISM; THROMBOXANE A2;

MUS; SPATHOLOBUS;

EID: 79952694415     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2010.12.039     Document Type: Article

References (53)

1. Altman, R., 2007. Antithrombotic prevention in vascular disease: bases for a new strategy in antithrombotic therapy. Thrombosis Journal 5, 11.
2. Asmis, L., Tanner, F.C., Sudano, I., Lüscher, T.F., Camici, G.G., 2010. DMSO inhibits human platelet activation through cyclooxygenase-1 inhibition. A novel agent for drug eluting stents? Biochemical and Biophysical Research Communications 391, 1629-1633.
3. Ballabeni, V., Tognolini, M., Chiavarini, M., Impicciatore, M., Bruni, R., Bianchi, A., Barocelli, E., 2004. Novel antiplatelet and antithrombotic activities of essential oil from Lavandula hybrida Reverchon "grosso". Phytomedicine 11, 596-601.
4. Bates, S.M., Weitz, J.I., 2005. Coagulation assays. Circulation 112, e53-e60.
5. Bhatt, D.L., Topol, E.J., 2003. Scientific and therapeutic advances in antiplatelet therapy. Nature Reviews. Drug Discovery 2, 15-28. (Pubitemid 37361621)
6. Born, G.V.R., Wehmeier, A., 1979. Inhibition of platelet thrombus formation by chlorpromazine acting to diminish haemolysis. Nature 282, 212-213. (Pubitemid 10196514)
7. Cattaneo, M., Gachet, C., 2001. The platelet ADP receptors. Haematologica 86, 346-348. (Pubitemid 32428490)
8. Cui, Y.J., Liu, P., Chen, R.Y., 2005. Studies on the active constituents in vine stem of Spatholobus suberectus. Zhongguo Zhong Yao Za Zhi 30, 121-123. (Pubitemid 44794068)
9. Dale, H.C., Abel, L.R., Patricia, S., Paul, G., 1981. Platelet adherence to collagen: role of plasma, ADP, and divalent cations. British Journal of Haematology 47, 257-267.
10. Davi, G., Patrono, C., 2007. Platelet activation and atherothrombosis. The New England Journal of Medicine 357, 2482-2494.
11. Dennis, M.S., Henzel, W.J., Pitti, R.M., Lipari, M.T., Napier, M.A., Deisher, T.A., Bunting, S., Lazarus, R.A., 1990. Platelet glycoprotein IIb-IIIa protein antagonists from snake venoms: evidence for a family of platelet-aggregation inhibitors. Proceedings of the National Academy of Sciences of the United States of America 87, 2471-2475.
12. DiMinno, G., Silver, M.J., 1983. Mouse antithrombotic assay: a simple method for the evaluation of antithrombotic agents in vivo. Potentiation of antithrombotic activity by ethyl alcohol. The Journal of Pharmacology and Experimental Therapeutics 225, 57-60. (Pubitemid 13137003)
13. Eisenberg, P.R., Ghigliotti, G., 1999. Platelet-dependent and procoagulant mechanisms in arterial thrombosis. International Journal of Cardiology 68 (Suppl. 1), S3-S10. (Pubitemid 29197190)
14. Fan, E., Zhang, L., Jiang, S., Bai, Y., 2008. Beneficial effects of resveratrol on atherosclerosis. Journal of Medicinal Food 11, 610-614.
15. Frishman, W.H., Burns, B., Atac, B., Alturk, N., Altajar, B., Lerrick, K., 1995. Novel antiplatelet therapies for treatment of patients with ischemic heart disease: inhibitors of the platelet glycoprotein IIb/IIIa integrin receptor. American Heart Journal 130, 877-892.
16. Furie, B., Furie, B.C., 2007. In vivo thrombus formation. Journal of Thrombosis and Haemostasis 5 (Suppl. 1), 12-17.
17. George, J.N., 2000. Platelets. Lancet 355, 1531-1539. (Pubitemid 30237365)
18. Gottstein, N., Ewins, B.A., Eccleston, C., Hubbard, G.P., Kavanagh, I.C., Minihane, A.M., Weinberg, P.D., Rimbach, G., 2003. Effect of genistein and daidzein on platelet aggregation and monocyte and endothelial function. British Journal of Nutrition 89, 607-616.
19. Gresele, P., Corona, C., Alberti, P., Nenci, G.G., 1990. Picotamide protects mice from death in a pulmonary embolism model by a mechanism independent from thromboxane suppression. Thrombosis and Haemostasis 64, 80-86. (Pubitemid 20301854)
20. Hara, T., Yokoyama, A., Ishihara, H., Yokoyama, Y., Nagahara, T., Iwamoto, M., 1994. DX-9065a, a new synthetic, potent anticoagulant and selective inhibitor for factor Xa. Thrombosis and Haemostasis 71, 314-319. (Pubitemid 24083741)
21. Herman, A.G., 1998. Rationale for the combination of anti-aggregating drugs. Thrombosis Research 92, S17-S21. (Pubitemid 28480218)
22. Jennings, L.K., 2009. Role of platelets in atherothrombosis. The American Journal of Cardiology 103, 4A-10A.
23. Jeon, W.K., Kim, J.H., Lee, A.O., Kim, H.K., 2003. Inhibition of whole blood platelet aggregation from traditional medicines. Korean Journal of Oriental Medicine 9, 55-67.
24. Kang, I.C., Kim, S.A., Song, G.Y., Baek, N.I., Park, Y.D., Ryu, S.Y., Sakai, I., Kim, S.H., 2003. Effects of the ethyl acetate fraction of Spatholobi caulis on tumour cell aggregation and migration. Phytotherapy Research 17, 163-167. (Pubitemid 36262267)
25. Kudolo, G.B., Dorsey, S., Blodgett, J., 2002. Effect of the ingestion of Ginkgo biloba extract on platelet aggregation and urinary prostanoid excretion in healthy and Type 2 diabetic subjects. Thrombosis Research 108, 151-160. (Pubitemid 36184651)
26. Lau, A.J., Toh, D.F., Chua, T.K., Pang, Y.K., Woo, S.O., Koh, H.L., 2009. Antiplatelet and anticoagulant effects of Panax notoginseng: comparison of raw and steamed Panax notoginseng with Panax ginseng and Panax quinquefolium. Journal of Ethnopharmacology 125, 380-386.
27. Lee, M.H., Lin, Y.P., Hsu, F.L., Zhan, G.R., Yen, K.Y., 2006. Bioactive constituents of Spatholobus suberectus in regulating tyrosinase-related proteins and mRNA in HEMn cells. Phytochemistry 67, 1262-1270.
28. Lee, S.L., Choi, C.H., Jin, U.B., Youn, D.H., Jeong, S.H., Han, U., Jeong, H.W., Kim, G.Y., 2007. Experimental study of Spatholobi caulis on the transient cerebral ischemia in rats. Korean Journal of Oriental Physiology and Pathology 5, 1127-1134.
29. Lee, S.L., Jeong, H.W., 2006. Experimental effects of Spatholbi caulis on the cerebral blood flow and lactate dehydrogenase activity. Korean Journal of Oriental Physiology and Pathology 20, 25-30.
30. Liao, F., 2000. Herbs of activating blood circulation to remove blood stasis. Clinical Hemorheology and Microcirculation 23, 127-131. (Pubitemid 32274595)
31. Liu, P., Wang, D.X., Chen, R.Y., Chen, M.L., Yin, J.F., Chen, G.Y., 2004. Effect of catechin bone marrow cell cycle and gene expression of hematopoietic growth factors. Yao Xue Xue Bao 39, 424-428. (Pubitemid 39420691)
32. Michelson, A.D., Barnard, M.R., Krueger, L.A., Frelinger, A.L., Furman, M.I., 2006. Evaluation of platelet function by flow cytometry. Pathophysiology of Haemostasis and Thrombosis 35, 67-82.
33. Nishizawa, E.E., Wynalda, D.J., Suydam, D.E., Sawa, T.R., Schultz, J.R., 1972. Collagen-induced pulmonary thromboembolism in mice. Thrombosis Research 1, 233-241.
34. Packham, M.A., 1994. Role of platelets in thrombosis and hemostasis. Canadian Journal of Physiology and Pharmacology 72, 278-284. (Pubitemid 24181930)
35. Parise, L.V., Venton, D.L., Le Breton, G.C., 1984. Arachidonic acid-induced platelet aggregation is mediated by a thromboxane A2/prostaglandin H2 receptor interaction. Journal of Pharmacology and Experimental Therapeutics 228, 240-244. (Pubitemid 14223408)
36. Pepine, C.J., 2010. Residual risk for secondary ischemic events in patients with atherothrombotic disease: opportunity for future improvements in patient care. Annals of Medicine 42, 19-35.
37. 3) Inhibitors. Blood 92, 3240-3249.
38. Phillips, D.R., Charo, I., Parise, L., Fitzgerald, L., 1988. The platelet membrane glycoprotein IIb-IIIa complex. Blood 71, 831-843.
39. Phillips, D.R., Conley, P.B., Sinha, U., Andre, P., 2005. Therapeutic approaches in arterial thrombosis. Journal of Thrombosis and Haemostasis 3, 1577-1589. (Pubitemid 41716542)
40. Rahman, K., 2007. Effects of garlic on platelet biochemistry and physiology. Molecular Nutrition and Food Research 51, 1335-1344. (Pubitemid 350195607)
41. Rand, M.L., Leung, R., Packham, M.A., 2003. Platelet function assays. Transfusion and Apheresis Science 28, 307-317. (Pubitemid 36506506)
42. Rezkalla, S.H., Benz, M., 2003. Antiplatelet therapy from clinical trials to clinical practice. Clinical Medicine and Research 1, 101-104.
43. Saeed, S.A., Karimi, S.J., Suria, A., 1988. Differential effects of dimethyl sulfoxide on human platelet aggregation and arachidonic acid metabolism. Biochemical Medicine and Metabolic Biology 40, 143-150. (Pubitemid 18261793)
44. Sarratt, K.L., Chen, H., Zutter, M.M., Santoro, S.A., Hammer, D.A., Kahn, M.L., 2005. GPVI and alpha2beta1 play independent critical roles during platelet adhesion and aggregate formation to collagen under flow. Blood 106, 1268-1277. (Pubitemid 41129590)
45. Schrör, K., 1995. Antiplatelet drugs: a comparative review. Drugs 50, 7-28.
46. Stassen, J.M., Amout, J., Deckmyn, H., 2004. The hemostatic system. Current Medicinal Chemistry 11, 2245-2260. (Pubitemid 39172347)
47. Steinhubl, S.R., Moliterno, D.J., 2005. The role of the platelet in the pathogenesis of atherothrombosis. American Journal of Cardiovascular Drugs: Drugs, Devices, and Other Interventions 5, 399-408. (Pubitemid 41584840)
48. Su, E., Chen, H., 1997. Clinical observation on aplastic anemia treated by Spatholobus Suberectus composita. Chinese Journal of Integrated Traditional and Western Medicine 17, 213-215.
49. Tang, Z., Zeng, Y., Zhou, Y., He, P., Fang, Y., Zang, S., 2007. Determination of active ingredients of Spatholobus Suberectus Dunn and its medicinal preparations by capillary electrophoresis with electrochemical detection. Journal of Liquid Chromatography and Related Technologies 30, 59-71. (Pubitemid 46005184)
50. Tian, Y., Yang, Z.F., Li, Y., Qiao, Y., Yang, J., Jia, Y.Y., Wen, A.D., 2010. Pharmacokinetic comparisons of hydroxysafflower yellow A in normal and blood stasis syndrome rats. Journal of Ethnopharmacology 129, 1-4.
51. Varon, D., Spectre, G., 2009. Antiplatelet agents. American Society of Hematology Education Program 2009, 267-272.
52. Vorchheimer, D.A., Becker, R., 2006. Platelets in Atherothrombosis. Mayo Clinic Proceedings. Mayo Clinic 81, 59-68. (Pubitemid 43054319)
53. Wang, W., Wang, J., Zhao, D., Liu, H., Zhou, W., Chen, K., 1991. Comparison of Spatholobus suberectus Dunn, Euonymus alatus (Thunb.) Sieb. and Eupolyphaga sinensis Walker on regulation of plasma lipid. Zhongguo Zhong Yao Za Zhi 16, 299-301, 320.