-
1
-
-
34447282985
-
Characteristics of lentiviral vectors harboring the proximal promoter of the vav proto-oncogene: A weak and efficient promoter for gene therapy
-
DOI 10.1038/sj.mt.6300213, PII 6300213
-
Almarza, E., Rio, P., Meza, N.W., et al. (2007). Characteristics of lentiviral vectors harboring the proximal promoter of the vav proto-oncogene: A weak and efficient promoter for gene therapy. Mol. Ther. 15, 1487-1494. (Pubitemid 47099306)
-
(2007)
Molecular Therapy
, vol.15
, Issue.8
, pp. 1487-1494
-
-
Almarza, E.1
Rio, P.2
Meza, N.W.3
Aldea, M.4
Agirre, X.5
Guenechea, G.6
Segovia, J.C.7
Bueren, J.A.8
-
2
-
-
79952670909
-
Of SCID-X1 using an enhancerless Vav promoter
-
Almarza, E., Zhang, F., Santilli, G., et al. (2011). Correction of SCID-X1 using an enhancerless Vav promoter. Hum. Gene Ther. 22, 263-270.
-
(2011)
Hum. Gene Ther.
, vol.22
, pp. 263-270
-
-
Almarza, E.1
Zhang, F.2
Santilli, G.3
-
3
-
-
33646564701
-
Endogenous microRNA regulation suppresses transgene expression in hematopoietic lineages and enables stable gene transfer
-
Brown, B.D., Venneri, M.A., Zingale, A., et al. (2006). Endogenous microRNA regulation suppresses transgene expression in hematopoietic lineages and enables stable gene transfer. Nat. Med. 12, 585-591.
-
(2006)
Nat. Med.
, vol.12
, pp. 585-591
-
-
Brown, B.D.1
Venneri, M.A.2
Zingale, A.3
-
4
-
-
67149105856
-
Murine leuke-mias with retroviral insertions at LMO2 are predictive of the leukemias induced in SCID-X1 patients following retroviral gene therapy
-
Dave, U.P., Akagi, K., Tripathi, R., et al. (2009). Murine leuke-mias with retroviral insertions at LMO2 are predictive of the leukemias induced in SCID-X1 patients following retroviral gene therapy. PLoS Genet. 5, e1000491.
-
(2009)
PLoS Genet.
, vol.5
-
-
Dave, U.P.1
Akagi, K.2
Tripathi, R.3
-
5
-
-
0344872674
-
Chimeric transcriptional control units for improved liver-specific transgene expression
-
DOI 10.1016/j.gene.2003.08.010
-
Gehrke, S., Jerome, V., and Muller, R. (2003). Chimeric tran-scriptional control units for improved liver-specific transgene expression. Gene 322, 137-143. (Pubitemid 37485990)
-
(2003)
Gene
, vol.322
, Issue.1-2
, pp. 137-143
-
-
Gehrke, S.1
Jerome, V.2
Muller, R.3
-
6
-
-
77952009127
-
Lymphomagenesis in SCID-X1 mice following lentivirus-mediated phenotype correction independent of insertional mutagenesis and gc overexpression
-
Ginn, S.L., Liao, S.H., Dane, A.P., et al. (2010). Lymphomagenesis in SCID-X1 mice following lentivirus-mediated phenotype correction independent of insertional mutagenesis and gc overexpression. Mol. Ther. 18, 965-976.
-
(2010)
Mol. Ther.
, vol.18
, pp. 965-976
-
-
Ginn, S.L.1
Liao, S.H.2
Dane, A.P.3
-
7
-
-
31444433490
-
Synthetic promoter libraries - Tuning of gene expression
-
DOI 10.1016/j.tibtech.2005.12.003, PII S0167779905003264
-
Hammer, K., Mijakovic, I., and Jensen, P.R. (2006). Synthetic promoter libraries-tuning of gene expression. Trends Bio-technol. 24, 53-55. (Pubitemid 43151974)
-
(2006)
Trends in Biotechnology
, vol.24
, Issue.2
, pp. 53-55
-
-
Hammer, K.1
Mijakovic, I.2
Jensen, P.R.3
-
8
-
-
79952678001
-
Lentiviral gene transfer regenerates hematopoietic stem cells in a mouse model for Mpl-deficient aplastic anemia
-
in press
-
Heckl, D., Wicke, D.C., Brugman, M.H., et al. (2011). Lentiviral gene transfer regenerates hematopoietic stem cells in a mouse model for Mpl-deficient aplastic anemia. Blood (in press
-
(2011)
Blood
-
-
Heckl, D.1
Wicke, D.C.2
Brugman, M.H.3
-
9
-
-
0026264296
-
Gene targeting and gene trap screens using embryonic stem cells: New approaches to mammalian development
-
Joyner, A.L. (1991). Gene targeting and gene trap screens using embryonic stem cells: New approaches to mammalian development. Bioessays 13, 649-656. (Pubitemid 21892587)
-
(1991)
BioEssays
, vol.13
, Issue.12
, pp. 649-656
-
-
Joyner, A.L.1
-
10
-
-
70449127230
-
Insertional transformation of hematopoietic cells by self-inactivating len-tiviral and gammaretroviral vectors
-
Modlich, U., Navarro, S., Zychlinski, D., et al. (2009). Insertional transformation of hematopoietic cells by self-inactivating len-tiviral and gammaretroviral vectors. Mol. Ther. 17, 1919-1928.
-
(2009)
Mol. Ther.
, vol.17
, pp. 1919-1928
-
-
Modlich, U.1
Navarro, S.2
Zychlinski, D.3
-
11
-
-
58149469932
-
phox expression and reconstitution of superoxide production in X-CGD cells
-
phox expression and reconstitution of superoxide production in X-CGD cells. Gene Ther. 16, 111-118.
-
(2009)
Gene Ther.
, vol.16
, pp. 111-118
-
-
Moreno-Carranza, B.1
Gentsch, M.2
Stein, S.3
-
12
-
-
33947395708
-
Ectopic retroviral expression of LMO2, but not IL2Rγ, blocks human T-cell development from CD34+ cells: Implications for leukemogenesis in gene therapy
-
DOI 10.1038/sj.leu.2404563, PII 2404563
-
\+ cells: Implications for leukemogenesis in gene therapy. Leukemia 21, 754-763. (Pubitemid 46444560)
-
(2007)
Leukemia
, vol.21
, Issue.4
, pp. 754-763
-
-
Pike-Overzet, K.1
De Ridder, D.2
Weerkamp, F.3
Baert, M.R.M.4
Verstegen, M.M.A.5
Brugman, M.H.6
Howe, S.J.7
Reinders, M.J.T.8
Thrasher, A.J.9
Wagemaker, G.10
Van Dongen, J.J.M.11
Staal, F.J.T.12
-
13
-
-
34249298695
-
Improving transcriptional termination of self-inactivating gamma-retroviral and lentiviral vectors
-
DOI 10.1038/sj.mt.6300152, PII 6300152
-
Schambach, A., Galla, M., Maetzig, T., et al. (2007). Improving transcriptional termination of self-inactivating gamma-retroviral and lentiviral vectors. Mol. Ther. 15, 1167-1173. (Pubitemid 46813620)
-
(2007)
Molecular Therapy
, vol.15
, Issue.6
, pp. 1167-1173
-
-
Schambach, A.1
Galla, M.2
Maetzig, T.3
Loew, R.4
Baum, C.5
-
14
-
-
67349162619
-
A novel model of SCID-X1 reconstitution reveals predisposition to retrovirus-induced lymphoma but no evidence of gc gene oncogenicity
-
Scobie, L., Hector, R.D., Grant, L., et al. (2009). A novel model of SCID-X1 reconstitution reveals predisposition to retrovirus-induced lymphoma but no evidence of gc gene oncogenicity. Mol. Ther. 17, 1031-1038.
-
(2009)
Mol. Ther.
, vol.17
, pp. 1031-1038
-
-
Scobie, L.1
Hector, R.D.2
Grant, L.3
-
15
-
-
67649826220
-
From DNA sequence to tran-scriptional behaviour: A quantitative approach
-
Segal, E., and Widom, J. (2009). From DNA sequence to tran-scriptional behaviour: A quantitative approach. Nat. Rev. Genet. 10, 443-456.
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 443-456
-
-
Segal, E.1
Widom, J.2
-
16
-
-
39849110286
-
Self-inactivating gammaretroviral vectors for gene therapy of x-linked severe combined immunodeficiency
-
DOI 10.1038/sj.mt.6300393, PII 6300393
-
Thornhill, S.I., Schambach, A., Howe, S.J., et al. (2008). Self-inactivating gammaretroviral vectors for gene therapy of X-linked severe combined immunodeficiency. Mol. Ther. 16, 590-598. (Pubitemid 351315000)
-
(2008)
Molecular Therapy
, vol.16
, Issue.3
, pp. 590-598
-
-
Thornhill, S.I.1
Schambach, A.2
Howe, S.J.3
Ulaganathan, M.4
Grassman, E.5
Williams, D.6
Schiedlmeier, B.7
Sebire, N.J.8
Gaspar, H.B.9
Kinnon, C.10
Baum, C.11
Thrasher, A.J.12
-
17
-
-
33646361846
-
Gene therapy: Therapeutic gene causing lymphoma
-
Woods, N.B., Bottero, V., Schmidt, M., et al. (2006). Gene therapy: Therapeutic gene causing lymphoma. Nature 440, 1123.
-
(2006)
Nature
, vol.440
, pp. 1123
-
-
Woods, N.B.1
Bottero, V.2
Schmidt, M.3
-
18
-
-
34548843603
-
Lentiviral vectors containing an enhancer-less ubiquitously acting chromatin opening element (UCOE) provide highly reproducible and stable transgene expression in hematopoietic cells
-
DOI 10.1182/blood-2006-12-060814
-
Zhang, F., Thornhill, S.I., Howe, S.J., et al. (2007). Lentiviral vectors containing an enhancer-less ubiquitously acting chromatin opening element (UCOE) provide highly reproducible and stable transgene expression in hematopoietic cells. Blood 110, 1448-1457. (Pubitemid 47443959)
-
(2007)
Blood
, vol.110
, Issue.5
, pp. 1448-1457
-
-
Zhang, F.1
Thornhill, S.I.2
Howe, S.J.3
Ulaganathan, M.4
Schambach, A.5
Sinclair, J.6
Kinnon, C.7
Gaspar, H.B.8
Antoniou, M.9
Thrasher, A.J.10
-
19
-
-
77956502744
-
A self-inactivating lentiviral vector for SCID-X1 gene therapy that does not activate LMO2 expression in human t cells
-
Zhou, S., Mody, D., Deravin, S.S., et al. (2010). A self-inactivating lentiviral vector for SCID-X1 gene therapy that does not activate LMO2 expression in human t cells. Blood 116, 900-908.
-
(2010)
Blood
, vol.116
, pp. 900-908
-
-
Zhou, S.1
Mody, D.2
Deravin, S.S.3
-
20
-
-
0032978712
-
Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors
-
Zufferey, R., Donello, J.E., Trono, D., and Hope, Z.J. (1999). Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by ret-roviral vectors. J. Virol. 73, 2886-2892. (Pubitemid 29135675)
-
(1999)
Journal of Virology
, vol.73
, Issue.4
, pp. 2886-2892
-
-
Zufferey, R.1
Donello, J.E.2
Trono, D.3
Hope, T.J.4
|