-
1
-
-
51349092937
-
Tumor stroma as a target in cancer
-
Ahmed F., Steele J.C., Herbert J.M., Steven N.M., Bicknell R. Tumor stroma as a target in cancer. Curr. Cancer Drug Targets 2008, 8:447-453.
-
(2008)
Curr. Cancer Drug Targets
, vol.8
, pp. 447-453
-
-
Ahmed, F.1
Steele, J.C.2
Herbert, J.M.3
Steven, N.M.4
Bicknell, R.5
-
2
-
-
0034648765
-
Angiogenesis in cancer and other diseases
-
Carmeliet P., Jain R.K. Angiogenesis in cancer and other diseases. Nature 2000, 407:249-257.
-
(2000)
Nature
, vol.407
, pp. 249-257
-
-
Carmeliet, P.1
Jain, R.K.2
-
3
-
-
0032950870
-
Anti-vascular approaches to solid tumour therapy: evaluation of combretastatin A4 phosphate
-
Chaplin D.J., Pettit G.R., Hill S.A. Anti-vascular approaches to solid tumour therapy: evaluation of combretastatin A4 phosphate. Anticancer Res. 1999, 19:189-195.
-
(1999)
Anticancer Res.
, vol.19
, pp. 189-195
-
-
Chaplin, D.J.1
Pettit, G.R.2
Hill, S.A.3
-
4
-
-
0025337015
-
Invasive blood pressure measurements in restrained but non-anaesthetized mice
-
Christensen K.L., Horsman M.R., Overgaard J. Invasive blood pressure measurements in restrained but non-anaesthetized mice. In Vivo 1990, 4:13-16.
-
(1990)
In Vivo
, vol.4
, pp. 13-16
-
-
Christensen, K.L.1
Horsman, M.R.2
Overgaard, J.3
-
5
-
-
34249852766
-
Unrestrained erythroblast development in Nix-/- mice reveals a mechanism for apoptotic modulation of erythropoiesis
-
Diwan A., Koesters A.G., Odley A.M., Pushkaran S., Baines C.P., Spike B.T., Daria D., Jegga A.G., Geiger H., Aronow B.J., Molkentin J.D., Macleod K.F., Kalfa T.A., Dorn G.W. Unrestrained erythroblast development in Nix-/- mice reveals a mechanism for apoptotic modulation of erythropoiesis. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:6794-6799.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 6794-6799
-
-
Diwan, A.1
Koesters, A.G.2
Odley, A.M.3
Pushkaran, S.4
Baines, C.P.5
Spike, B.T.6
Daria, D.7
Jegga, A.G.8
Geiger, H.9
Aronow, B.J.10
Molkentin, J.D.11
Macleod, K.F.12
Kalfa, T.A.13
Dorn, G.W.14
-
6
-
-
0025862097
-
Hydralazine-induced changes in tissue perfusion and radiation response in a C3H mammary carcinoma and mouse normal tissues
-
Fisker R.V., Horsman M.R., Overgaard J. Hydralazine-induced changes in tissue perfusion and radiation response in a C3H mammary carcinoma and mouse normal tissues. Acta Oncol. 1991, 30:641-647.
-
(1991)
Acta Oncol.
, vol.30
, pp. 641-647
-
-
Fisker, R.V.1
Horsman, M.R.2
Overgaard, J.3
-
7
-
-
33748869678
-
Pathophysiologic effects of vascular-targeting agents and the implications for combination with conventional therapies
-
Horsman M.R., Siemann D.W. Pathophysiologic effects of vascular-targeting agents and the implications for combination with conventional therapies. Cancer Res. 2006, 66:11520-11539.
-
(2006)
Cancer Res.
, vol.66
, pp. 11520-11539
-
-
Horsman, M.R.1
Siemann, D.W.2
-
8
-
-
0024531650
-
Hydralazine-induced enhancement of hyperthermic damage in a C3H mammary carcinoma in vivo
-
Horsman M.R., Christensen K.L., Overgaard J. Hydralazine-induced enhancement of hyperthermic damage in a C3H mammary carcinoma in vivo. Int. J. Hyperthermia 1989, 5:123-136.
-
(1989)
Int. J. Hyperthermia
, vol.5
, pp. 123-136
-
-
Horsman, M.R.1
Christensen, K.L.2
Overgaard, J.3
-
9
-
-
0026600356
-
Relationship between the hydralazine-induced changes in murine tumor blood supply and mouse blood pressure
-
Horsman M.R., Christensen K.L., Overgaard J. Relationship between the hydralazine-induced changes in murine tumor blood supply and mouse blood pressure. Int. J. Radiat. Oncol. Biol. Phys. 1992, 22:455-458.
-
(1992)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.22
, pp. 455-458
-
-
Horsman, M.R.1
Christensen, K.L.2
Overgaard, J.3
-
10
-
-
0030042371
-
Splenic contraction, catecholamine release, and blood volume redistribution during diving in the Weddell seal
-
Hurford W.E., Hochachka P.W., Schneider R.C., Guyton G.P., Stanek K.S., Zapol D.G., Liggins G.C., Zapol W.M. Splenic contraction, catecholamine release, and blood volume redistribution during diving in the Weddell seal. J. Appl. Physiol. 1996, 80:298-306.
-
(1996)
J. Appl. Physiol.
, vol.80
, pp. 298-306
-
-
Hurford, W.E.1
Hochachka, P.W.2
Schneider, R.C.3
Guyton, G.P.4
Stanek, K.S.5
Zapol, D.G.6
Liggins, G.C.7
Zapol, W.M.8
-
11
-
-
70449109160
-
Pharmacological inhibition of the hypertensive response to combretastatin A-4 phosphate in rats
-
Ke Q., Bodyak N., Rigor D.L., Hurst N.W., Chaplin D.J., Kang P.M. Pharmacological inhibition of the hypertensive response to combretastatin A-4 phosphate in rats. Vascul. Pharmacol. 2009, 51:337-343.
-
(2009)
Vascul. Pharmacol.
, vol.51
, pp. 337-343
-
-
Ke, Q.1
Bodyak, N.2
Rigor, D.L.3
Hurst, N.W.4
Chaplin, D.J.5
Kang, P.M.6
-
12
-
-
0036780251
-
Clinical translation of angiogenesis inhibitors
-
Kerbel R., Folkman J. Clinical translation of angiogenesis inhibitors. Nat. Rev. Cancer 2002, 2:727-739.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 727-739
-
-
Kerbel, R.1
Folkman, J.2
-
13
-
-
0035889331
-
Combretastatin A-4 disodium phosphate: a vascular targeting agent that improves that improves the anti-tumor effects of hyperthermia, radiation, and mild thermoradiotherapy
-
Murata R., Overgaard J., Horsman M.R. Combretastatin A-4 disodium phosphate: a vascular targeting agent that improves that improves the anti-tumor effects of hyperthermia, radiation, and mild thermoradiotherapy. Int. J. Radiat. Oncol. Biol. Phys. 2001, 51:1018-1024.
-
(2001)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.51
, pp. 1018-1024
-
-
Murata, R.1
Overgaard, J.2
Horsman, M.R.3
-
14
-
-
0034759198
-
Improved tumor response by combining radiation and the vascular-damaging drug 5, 6-dimethylxanthenone-4-acetic acid
-
Murata R., Siemann D.W., Overgaard J., Horsman M.R. Improved tumor response by combining radiation and the vascular-damaging drug 5, 6-dimethylxanthenone-4-acetic acid. Radiat. Res. 2001, 156:503-509.
-
(2001)
Radiat. Res.
, vol.156
, pp. 503-509
-
-
Murata, R.1
Siemann, D.W.2
Overgaard, J.3
Horsman, M.R.4
-
15
-
-
0034962379
-
Interaction between combretastatin A-4 disodium phosphate and radiation in murine tumors
-
Murata R., Siemann D.W., Overgaard J., Horsman M.R. Interaction between combretastatin A-4 disodium phosphate and radiation in murine tumors. Radiother. Oncol. 2001, 60:155-161.
-
(2001)
Radiother. Oncol.
, vol.60
, pp. 155-161
-
-
Murata, R.1
Siemann, D.W.2
Overgaard, J.3
Horsman, M.R.4
-
16
-
-
39049125026
-
Preclinical studies to predict efficacy of vascular changes induced by combretastatin A-4 disodium phosphate in patients
-
Nielsen T., Murata R., Maxwell R.J., Stodkilde-Jorgensen H., Ostergaard L., Horsman M.R. Preclinical studies to predict efficacy of vascular changes induced by combretastatin A-4 disodium phosphate in patients. Int. J. Radiat. Oncol. Biol. Phys. 2008, 70:859-866.
-
(2008)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.70
, pp. 859-866
-
-
Nielsen, T.1
Murata, R.2
Maxwell, R.J.3
Stodkilde-Jorgensen, H.4
Ostergaard, L.5
Horsman, M.R.6
-
17
-
-
0019208702
-
Simultaneous and sequential hyperthermia and radiation treatment of an experimental tumor and its surrounding normal tissue in vivo
-
Overgaard J. Simultaneous and sequential hyperthermia and radiation treatment of an experimental tumor and its surrounding normal tissue in vivo. Int. J. Radiat. Oncol. Biol. Phys. 1980, 6:1507-1517.
-
(1980)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.6
, pp. 1507-1517
-
-
Overgaard, J.1
-
18
-
-
84995018742
-
Circulatory effects of splenectomy in the horse. I. Effect on red-cell distribution and variability of haematocrit in the peripheral blood
-
Persson S.G., Ekman L., Lydin G., Tufvesson G. Circulatory effects of splenectomy in the horse. I. Effect on red-cell distribution and variability of haematocrit in the peripheral blood. Zentralbl. Veterinarmed. A. 1973, 20:441-455.
-
(1973)
Zentralbl. Veterinarmed. A.
, vol.20
, pp. 441-455
-
-
Persson, S.G.1
Ekman, L.2
Lydin, G.3
Tufvesson, G.4
-
19
-
-
84995007691
-
Circulatory effects of splenectomy in the horse. II. Effect on plasma volume and total and circulating red-cell volume
-
Persson S.G., Ekman L., Lydin G., Tufvesson G. Circulatory effects of splenectomy in the horse. II. Effect on plasma volume and total and circulating red-cell volume. Zentralbl. Veterinarmed. A. 1973, 20:456-468.
-
(1973)
Zentralbl. Veterinarmed. A.
, vol.20
, pp. 456-468
-
-
Persson, S.G.1
Ekman, L.2
Lydin, G.3
Tufvesson, G.4
-
20
-
-
0036779867
-
The vascular response of tumor and normal tissues in the rat to the vascular targeting agent, combretastatin A-4-phosphate, at clinically relevant doses
-
Prise V.E., Honess D.J., Stratford M.R., Wilson J., Tozer G.M. The vascular response of tumor and normal tissues in the rat to the vascular targeting agent, combretastatin A-4-phosphate, at clinically relevant doses. Int. J. Oncol. 2002, 21:717-726.
-
(2002)
Int. J. Oncol.
, vol.21
, pp. 717-726
-
-
Prise, V.E.1
Honess, D.J.2
Stratford, M.R.3
Wilson, J.4
Tozer, G.M.5
-
21
-
-
58549090876
-
Hypoxia augments apnea-induced increase in hemoglobin concentration and hematocrit
-
Richardson M.X., de Bruijn R., Schagatay E. Hypoxia augments apnea-induced increase in hemoglobin concentration and hematocrit. Eur. J. Appl. Physiol. 2009, 105:63-68.
-
(2009)
Eur. J. Appl. Physiol.
, vol.105
, pp. 63-68
-
-
Richardson, M.X.1
de Bruijn, R.2
Schagatay, E.3
-
22
-
-
0042386700
-
Phase I clinical trial of weekly combretastatin A4 phosphate: clinical and pharmacokinetic results
-
Rustin G.J., Galbraith S.M., Anderson H., Stratford M., Folkes L.K., Sena L., Gumbrell L., Price P.M. Phase I clinical trial of weekly combretastatin A4 phosphate: clinical and pharmacokinetic results. J. Clin. Oncol. 2003, 21:2815-2822.
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 2815-2822
-
-
Rustin, G.J.1
Galbraith, S.M.2
Anderson, H.3
Stratford, M.4
Folkes, L.K.5
Sena, L.6
Gumbrell, L.7
Price, P.M.8
-
23
-
-
57749202046
-
Vascular targeted therapies in oncology
-
Siemann D.W., Horsman M.R. Vascular targeted therapies in oncology. Cell Tissue Res. 2009, 335:241-248.
-
(2009)
Cell Tissue Res.
, vol.335
, pp. 241-248
-
-
Siemann, D.W.1
Horsman, M.R.2
-
24
-
-
0036569804
-
Enhancement of radiation therapy by the novel vascular targeting agent ZD6126
-
Siemann D.W., Rojiani A.M. Enhancement of radiation therapy by the novel vascular targeting agent ZD6126. Int. J. Radiat. Oncol. Biol. Phys. 2002, 53:164-171.
-
(2002)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.53
, pp. 164-171
-
-
Siemann, D.W.1
Rojiani, A.M.2
-
25
-
-
2642571660
-
Vascular-targeting therapies for treatment of malignant disease
-
Siemann D.W., Chaplin D.J., Horsman M.R. Vascular-targeting therapies for treatment of malignant disease. Cancer 2004, 100:2491-2499.
-
(2004)
Cancer
, vol.100
, pp. 2491-2499
-
-
Siemann, D.W.1
Chaplin, D.J.2
Horsman, M.R.3
-
26
-
-
12244292196
-
Differentiation and definition of vascular-targeted therapies
-
Siemann D.W., Bibby M.C., Dark G.G., Dicker A.P., Eskens F.A., Horsman M.R., Marme D., Lorusso P.M. Differentiation and definition of vascular-targeted therapies. Clin. Cancer Res. 2005, 11:416-420.
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 416-420
-
-
Siemann, D.W.1
Bibby, M.C.2
Dark, G.G.3
Dicker, A.P.4
Eskens, F.A.5
Horsman, M.R.6
Marme, D.7
Lorusso, P.M.8
-
27
-
-
65549090459
-
A review and update of the current status of the vasculature-disabling agent combretastatin-A4 phosphate (CA4P)
-
Siemann D.W., Chaplin D.J., Walicke P.A. A review and update of the current status of the vasculature-disabling agent combretastatin-A4 phosphate (CA4P). Expert Opin. Investig. Drugs 2009, 18:189-197.
-
(2009)
Expert Opin. Investig. Drugs
, vol.18
, pp. 189-197
-
-
Siemann, D.W.1
Chaplin, D.J.2
Walicke, P.A.3
-
28
-
-
0033119771
-
Combretastatin A-4 phosphate as a tumor vascular-targeting agent: early effects in tumors and normal tissues
-
Tozer G.M., Prise V.E., Wilson J., Locke R.J., Vojnovic B., Stratford M.R., Dennis M.F., Chaplin D.J. Combretastatin A-4 phosphate as a tumor vascular-targeting agent: early effects in tumors and normal tissues. Cancer Res. 1999, 59:1626-1634.
-
(1999)
Cancer Res.
, vol.59
, pp. 1626-1634
-
-
Tozer, G.M.1
Prise, V.E.2
Wilson, J.3
Locke, R.J.4
Vojnovic, B.5
Stratford, M.R.6
Dennis, M.F.7
Chaplin, D.J.8
-
29
-
-
0035417875
-
Mechanisms associated with tumor vascular shut-down induced by combretastatin A-4 phosphate: intravital microscopy and measurement of vascular permeability
-
Tozer G.M., Prise V.E., Wilson J., Cemazar M., Shan S., Dewhirst M.W., Barber P.R., Vojnovic B., Chaplin D.J. Mechanisms associated with tumor vascular shut-down induced by combretastatin A-4 phosphate: intravital microscopy and measurement of vascular permeability. Cancer Res. 2001, 61:6413-6422.
-
(2001)
Cancer Res.
, vol.61
, pp. 6413-6422
-
-
Tozer, G.M.1
Prise, V.E.2
Wilson, J.3
Cemazar, M.4
Shan, S.5
Dewhirst, M.W.6
Barber, P.R.7
Vojnovic, B.8
Chaplin, D.J.9
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