Spinal 5-HT7 receptor activation induces long-lasting phrenic motor facilitation

Journal of Physiology

Volumn 589, Issue 6, 2011, Pages 1397-1407

  Hoffman, M S ^a   Mitchell, G S ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AS 19; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SEROTONIN 7 RECEPTOR; SEROTONIN AGONIST; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENZYME INHIBITION; FACILITATION; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHRENIC NERVE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; SIGNAL TRANSDUCTION;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; LONG-TERM POTENTIATION; MALE; MOTOR NEURONS; PHRENIC NERVE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, TRKB; RECEPTORS, SEROTONIN; SEROTONIN ANTAGONISTS; SEROTONIN RECEPTOR AGONISTS;

EID: 79952612101     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2010.201657     Document Type: Article

References (53)

1. Abbracchio MP & Cattabeni F (1999). Brain adenosine receptors as targets for therapeutic intervention in neurodegenerative diseases. Ann N Y Acad Sci 890, 79-92.
2. Baker-Herman TL, Fuller DD, Bavis RW, Zabka AG, Golder FJ, Doperalski NJ, Johnson RA, Watters JJ & Mitchell GS (2004). BDNF is necessary and sufficient for spinal respiratory plasticity following intermittent hypoxia. Nat Neurosci 7, 48-55.
3. Baker-Herman TL & Mitchell GS (2002). Phrenic long-term facilitation requires spinal serotonin receptor activation and protein synthesis. J Neurosci 22, 6239-6246.
4. Bass JL, Corwin M, Gozal D, Moore C, Nishida H, Parker S, Schonwald A, Wilker RE, Stehle S & Kinane TB (2004). The effect of chronic or intermittent hypoxia on cognition in childhood: a review of the evidence. Pediatrics 114, 805-816.
5. Berghuis P, Dobszay MB, Wang X, Spano S, Ledda F, Sousa KM, Schulte G, Ernfors P, Mackie K, Paratcha G, Hurd YL & Harkany T (2005). Endocannabinoids regulate interneuron migration and morphogenesis by transactivating the TrkB receptor. Proc Natl Acad Sci U S A 102, 19115-19120.
6. Chao MV (2003). Neurotrophins and their receptors: a convergence point for many signalling pathways. Nat Rev Neurosci 4, 299-309.
7. Dale-Nagle EA & Mitchell GS (2008). Intrathecal administration of vascular endothelial growth factor (VEGF) elicits phrenic motor facilitation. FASEB J 22, 1232.6 (abstract).
8. Davis HP & Squire LR (1984). Protein synthesis and memory: a review. Psychol Bull 96, 518-559.
9. Doly S, Fischer J, Brisorgueil MJ, Verge D & Conrath M (2005). Pre- and postsynaptic localization of the 5-HT7 receptor in rat dorsal spinal cord: immunocytochemical evidence. J Comp Neurol 490, 256-269.
10. Drummond GB (2009). Reporting ethical matters in The Journal of Physiology: standards and advice. J Physiol 587, 713-719.
11. Eldridge FL (1976). Quantification of electrical activity in the phrenic nerve in the study of ventilatory control. Chest 70(1 Suppl), 154-157.
12. 7 receptors activate the mitogen activated protein kinase extracellular signal related kinase in cultured rat hippocampal neurons. Neuroscience 102, 361-367.
13. Feldman JL, Mitchell GS & Nattie EE (2003). Breathing: rhythmicity, plasticity, chemosensitivity. Annu Rev Neurosci 26, 239-266.
14. Fuller DD, Zabka AG, Baker TL & Mitchell GS (2001). Phrenic long-term facilitation requires 5-HT receptor activation during but not following episodic hypoxia. J Appl Physiol 90, 2000-2006.
15. Golder FJ (2008). Receptor tyrosine kinases and respiratory motor plasticity. Respir Physiol Neurobiol 164, 242-251.
16. Golder FJ & Mitchell GS (2005). Spinal synaptic enhancement with acute intermittent hypoxia improves respiratory function after chronic cervical spinal cord injury. J Neurosci 25, 2925-2932.
17. Golder FJ, Ranganathan L, Satriotomo I, Hoffman M, Lovett-Barr MR, Watters JJ, Baker-Herman TL & Mitchell GS (2008). Spinal adenosine A2a receptor activation elicits long-lasting phrenic motor facilitation. J Neurosci 28, 2033-2042.
18. Goshgarian HG & Rafols JA (1981). The phrenic nucleus of the albino rat: a correlative HRP and Golgi study. J Comp Neurol 201, 441-456.
19. Gottschalk WA, Jiang H, Tartaglia N, Feng L, Figurov A & Lu B (1999). Signaling mechanisms mediating BDNF modulation of synaptic plasticity in the hippocampus. Learn Mem 6, 243-256.
20. Gozal D, Daniel JM & Dohanich GP (2001). Behavioral and anatomical correlates of chronic episodic hypoxia during sleep in the rat. J Neurosci 21, 2442-2450.
21. 2A receptor inhibition enhances phrenic long term facilitation following acute intermittent hypoxia. J Physiol 588, 255-266.
22. Horwood JM, Dufour F, Laroche S & Davis S (2006). Signalling mechanisms mediated by the phosphoinositide 3-kinase/Akt cascade in synaptic plasticity and memory in the rat. Eur J Neurosci 23, 3375-3384.
23. Kelleher RJ 3rd, Govindarajan A, Jung HY, Kang H & Tonegawa S (2004). Translational control by MAPK signaling in long-term synaptic plasticity and memory. Cell 116, 467-479.
24. Kishino A & Nakayama C (2003). Enhancement of BDNF and activated-ERK immunoreactivity in spinal motor neurons after peripheral administration of BDNF. Brain Res 964, 56-66.
25. Landry ES, Lapointe NP, Rouillard C, Levesque D, Hedlund PB & Guertin PA (2006). Contribution of spinal 5-HT1A and 5-HT7 receptors to locomotor-like movement induced by 8-OH-DPAT in spinal cord-transected mice. Eur J Neurosci 24, 535-546.
26. Lee FS & Chao MV (2001). Activation of Trk neurotrophin receptors in the absence of neurotrophins. Proc Natl Acad Sci U S A 98, 3555-3560.
27. Lee FS, Rajagopal R, Kim AH, Chang PC & Chao MV (2002a). Activation of Trk neurotrophin receptor signaling by pituitary adenylate cyclase-activating polypeptides. J Biol Chem 277, 9096-9102.
28. Lee FS, Rajagopal R & Chao MV (2002b). Distinctive features of Trk neurotrophin receptor transactivation by G protein-coupled receptors. Cytokine Growth Factor Rev 13, 11-17.
29. Lin SL, Johnson-Farley NN, Lubinsky DR & Cowen DS (2003). Coupling of neuronal 5-HT7 receptors to activation of extracellular-regulated kinase through a protein kinase A-independent pathway that can utilize Epac. J Neurochem 87, 1076-1085.
30. Lindsay AD & Feldman JL (1993). Modulation of respiratory activity of neonatal rat phrenic motoneurones by serotonin. J Physiol 461, 213-233.
31. Liu J, Akay T, Hedlund PB, Pearson KG & Jordan LM (2009). Spinal 5-HT7 receptors are critical for alternating activity during locomotion: in vitro neonatal and in vivo adult studies using 5-HT7 receptor knockout mice. J Neurophysiol 102, 337-348.
32. Macfarlane PM & Mitchell GS (2007). Respiratory long-term facilitation following intermittent hypoxia requires reactive oxygen species formation. Neuroscience 102, 337-348.
33. Mahamed S & Mitchell GS (2007). Is there a link between intermittent hypoxia-induced respiratory plasticity and obstructive sleep apnoea? Exp Physiol 92, 27-37.
34. Martin KC, Barad M & Kandel ER (2000). Local protein synthesis and its role in synapse-specific plasticity. Curr Opin Neurobiol 10, 587-592.
35. McGuire M, Zhang Y, White DP & Ling L (2004). Serotonin receptor subtypes required for ventilatory long-term facilitation and its enhancement after chronic intermittent hypoxia in awake rats. Am J Physiol Regul Integr Comp Physiol 286, R334-341.
36. Minghetti L, Greco A, Potenza RL, Pezzola A, Blum D, Bantubungi K & Popoli P (2007). Effects of the adenosine A2A receptor antagonist SCH 58621 on cyclooxygenase-2 expression, glial activation, and brain-derived neurotrophic factor availability in a rat model of striatal neurodegeneration. J Neuropathol Exp Neurol 66, 363-371.
37. Mitchell GS (2007). Respiratory plasticity following intermittent hypoxia: a guide for novel therapeutic approaches to ventilatory control disorders. In Genetic Basis for Respiratory Control Disorders, 1st edn, ed. Gaultier C, pp. 291-306. Springer, New York
38. Mitchell GS, Baker TL, Nanda SA, Fuller DD, Zabka AG, Hodgeman BA, Bavis RW, Mack KJ & Olson EB Jr (2001). Invited review: Intermittent hypoxia and respiratory plasticity. J Appl Physiol 90, 2466-2475.
39. Mitchell GS & Johnson SM (2003). Neuroplasticity in respiratory motor control. J Appl Physiol 94, 358-374.
40. Mojsilovic-Petrovic J, Jeong GB, Crocker A, Arneja A, David S, Russell DS & Kalb RG (2006). Protecting motor neurons from toxic insult by antagonism of adenosine A2a and Trk receptors. J Neurosci 26, 9250-9263.
41. Pedata F, Corsi C, Melani A, Bordoni F & Latini S (2001). Adenosine extracellular brain concentrations and role of A2A receptors in ischemia. Ann N Y Acad Sci 939, 74-84.
42. Perez-Garcia GS & Meneses A (2005). Effects of the potential 5-HT7 receptor agonist AS 19 in an autoshaping learning task. Behav Brain Res 163, 136-140.
43. Poduslo JF & Curran GL (1996). Permeability at the blood-brain and blood-nerve barriers of the neurotrophic factors: NGF, CNTF, NT-3, BDNF. Brain Res Mol Brain Res 36, 280-286.
44. Rajagopal R, Chen Z-Y, Lee FS & Chao MV (2004). Transactivation of Trk neurotrophin receptors by G-protein-coupled receptor ligands occurs on intracellular membranes. J Neurosci 24, 6650-6658.
45. Robinson DR, Wu YM & Lin SF (2000). The protein tyrosine kinase family of the human genome. Oncogene 19, 5548-5557.
46. Sajikumar S, Navakkode S & Frey JU (2005). Protein synthesis-dependent long-term functional plasticity: methods and techniques. Curr Opin Neurobiol 15, 607-613.
47. Sheng M & Hyoung Lee S (2003). AMPA receptor trafficking and synaptic plasticity: major unanswered questions. Neurosci Res 46, 127-134.
48. Tapley P, Lamballe F & Barbacid M (1992). K252a is a selective inhibitor of the tyrosine protein kinase activity of the trk family of oncogenes and neurotrophin receptors. Oncogene 7, 371-381.
49. Watson FL, Porcionatto MA, Bhattacharyya A, Stiles CD & Segal RA (1999). TrkA glycosylation regulates receptor localization and activity. J Neurobiol 39, 323-336.
50. Wiese S, Jablonka S, Holtmann B, Orel N, Rajagopal R, Chao MV & Sendtner M (2007). Adenosine receptor A2A-R contributes to motoneuron survival by transactivating the tyrosine kinase receptor TrkB. Proc Natl Acad Sci U S A 104, 17210-17215.
51. Wilkerson JE & Mitchell GS (2009). Daily intermittent hypoxia augments spinal BDNF levels, ERK phosphorylation and respiratory long-term facilitation. Exp Neurol 217, 116-123.
52. + channels in hippocampus involves a mitogen-activated protein kinase pathway. J Neurosci 22, 4860-4868.
53. Zhang Y, McGuire M, White DP & Ling L (2004). Serotonin receptor subtypes involved in vagus nerve stimulation-induced phrenic long-term facilitation in rats. Neurosci Lett 363, 108-111.