Tyrosine aminotransferase: Biochemical and structural properties and molecular dynamics simulations

Protein and Cell

Volumn 1, Issue 11, 2010, Pages 1023-1032

  Mehere, Prajwalini ^a   Han, Qian ^a   Lemkul, Justin A ^a   Vavricka, Christopher J ^a,b   Robinson, Howard ^c   Bevan, David R ^a   Li, Jianyong ^a  

^a VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

^b INSTITUTE OF MICROBIOLOGY   (China)

^c BROOKHAVEN NATIONAL LABORATORY   (United States)

Author keywords

crystal structure; substrate specificity; tyrosine; tyrosine aminotransferase; tyrosinemia

Indexed keywords

2 OXOACID; 2 OXOGLUTARIC ACID; 2 OXOHEXANOIC ACID; 4 HYDROXYPHENYLPYRUVIC ACID; GLUTAMIC ACID; PHENYLALANINE; PHENYLPYRUVIC ACID; TYROSINE AMINOTRANSFERASE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BACTERIAL CELL; BIOCHEMICAL COMPOSITION; CHEMICAL BOND; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; DNA LIBRARY; ENZYME ACTIVE SITE; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME REACTIVATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; HUMAN VERSUS NONHUMAN DATA; MOLECULAR CLONING; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PH MEASUREMENT; PRIORITY JOURNAL; PROTEIN PURIFICATION; STRUCTURE ANALYSIS; TRANSAMINATION; TRYPANOSOMA CRUZI; ANIMAL; CHEMISTRY; HUMAN; X RAY CRYSTALLOGRAPHY;

ESCHERICHIA COLI; TRYPANOSOMA CRUZI;

ANIMALS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; HUMANS; MICE; MOLECULAR DYNAMICS SIMULATION; TYROSINE TRANSAMINASE;

EID: 79952608066     PISSN: 1674800X     EISSN: 16748018     Source Type: Journal    
DOI: 10.1007/s13238-010-0128-5     Document Type: Article

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