Involvement of conserved asparagine and arginine residues from the N-terminal region in the catalytic mechanism of rat liver and Trypanosoma cruzi tyrosine aminotransferases

Protein Science

Volumn 12, Issue 5, 2003, Pages 1039-1050

  Sobrado, Verónica R ^a   Montemartini Kalisz, Marisa ^b,c   Kalisz, Henryk M ^b,c   De La Fuente, María Candelaria ^a   Hecht, Hans Jürgen ^b   Nowicki, Cristina ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^c Biology Department   (Italy)

Author keywords

Aromatic aminotransferases; Heterologous expression; Rat liver tyrosine aminotransferase; Site directed mutagenesis; Trypanosoma cruzi

Indexed keywords

ARGININE; ASPARAGINE; TYROSINE AMINOTRANSFERASE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; CATALYSIS; ENZYME ACTIVE SITE; ENZYME MECHANISM; LIVER; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; TRYPANOSOMA CRUZI;

AMINO ACID SEQUENCE; ANIMALS; ARGININE; ASPARAGINE; BINDING SITES; CATALYSIS; CONSERVED SEQUENCE; KINETICS; LIVER; MUTAGENESIS, SITE-DIRECTED; PROTOZOAN PROTEINS; RATS; SEQUENCE ALIGNMENT; SPECTRUM ANALYSIS; SUBSTRATE SPECIFICITY; TRYPANOSOMA CRUZI; TYROSINE TRANSAMINASE;

BACTERIA (MICROORGANISMS); PROTOZOA; TRYPANOSOMA; TRYPANOSOMA CRUZI;

EID: 0242432379     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.0229403     Document Type: Article

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