Hox gene Ultrabithorax regulates distinct sets of target genes at successive stages of Drosophila haltere morphogenesis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 7, 2011, Pages 2855-2860

  Pavlopoulos, Anastasios ^a   Akam, Michael ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Appendage specialization; Homeotic genes; Serial homology

Indexed keywords

TRANSCRIPTION FACTOR;

ARTICLE; CELL FUNCTION; DROSOPHILA; GENE EXPRESSION; HOX GENE; METAMORPHOSIS; MICROARRAY ANALYSIS; MORPHOGENESIS; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; ULTRABITHORAX GENE;

ANIMALS; CLUSTER ANALYSIS; DROSOPHILA; DROSOPHILA PROTEINS; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE REGULATORY NETWORKS; HOMEODOMAIN PROTEINS; IN SITU HYBRIDIZATION; LIFE CYCLE STAGES; MICROARRAY ANALYSIS; MORPHOGENESIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION FACTORS; WING;

ANIMALIA; DROSOPHILA MELANOGASTER;

EID: 79952593430     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1015077108     Document Type: Article

References (34)

1. McGinnis W, Krumlauf R (1992) Homeobox genes and axial patterning. Cell 68: 283-302.
2. Carroll SB, Grenier JK, Weatherbee SD (2005) From DNA to Diversity: Molecular Genetics and the Evolution of Animal Design (Blackwell, Oxford), 2nd Ed.
3. Graba Y, Aragnol D, Pradel J (1997) Drosophila Hox complex downstream targets and the function of homeotic genes. Bioessays 19:379-388. (Pubitemid 27218507)
4. Hombría JC, Lovegrove B (2003) Beyond homeosis - HOX function in morphogenesis and organogenesis. Differentiation 71:461-476.
5. Pearson JC, Lemons D, McGinnis W (2005) Modulating Hox gene functions during animal body patterning. Nat Rev Genet 6:893-904.
6. Hueber SD, Lohmann I (2008) Shaping segments: Hox gene function in the genomic age. Bioessays 30:965-979.
7. Foronda D, de Navas LF, Garaulet DL, Sánchez-Herrero E (2009) Function and specificity of Hox genes. Int J Dev Biol 53:1404-1419.
8. Mann RS, Lelli KM, Joshi R (2009) Hox specificity unique roles for cofactors and collaborators. Curr Top Dev Biol 88:63-101.
9. Lewis EB (1978) A gene complex controlling segmentation in Drosophila. Nature 276: 565-570.
10. White RA, Wilcox M (1985) Distribution of Ultrabithorax proteins in Drosophila. EMBO J 4:2035-2043.
11. Kelsh R, Weinzierl RO, White RA, Akam M (1994) Homeotic gene expression in the locust Schistocerca: An antibody that detects conserved epitopes in Ultrabithorax and abdominal-A proteins. Dev Genet 15:19-31. (Pubitemid 24079542)
12. Warren RW, Nagy L, Selegue J, Gates J, Carroll S (1994) Evolution of homeotic gene regulation and function in flies and butterflies. Nature 372:458-461.
13. Hughes CL, Kaufman TC (2002) Hox genes and the evolution of the arthropod body plan. Evol Dev 4:459-499. (Pubitemid 35442214)
14. CrickmoreMA, Mann RS (2006) Hox control of organ size by regulation of morphogen production and mobility. Science 313:63-68.
15. Roch F, Akam M (2000) Ultrabithorax and the control of cell morphology in Drosophila halteres. Development 127:97-107. (Pubitemid 30064392)
16. Carroll SB, Weatherbee SD, Langeland JA (1995) Homeotic genes and the regulation and evolution of insect wing number. Nature 375:58-61.
17. Weatherbee SD, Halder G, Kim J, Hudson A, Carroll S (1998) Ultrabithorax regulates genes at several levels of the wing-patterning hierarchy to shape the development of the Drosophila haltere. Genes Dev 12:1474-1482. (Pubitemid 28243632)
18. Weatherbee SD, et al. (1999) Ultrabithorax function in butterfly wings and the evolution of insect wing patterns. Curr Biol 9:109-115.
19. Galant R, Walsh CM, Carroll SB (2002) Hox repression of a target gene: Extradenticlein-dependent, additive action through multiple monomer binding sites. Development 129:3115-3126. (Pubitemid 34874286)
20. Prasad M, Bajpai R, Shashidhara LS (2003) Regulation of Wingless and Vestigial expression in wing and haltere discs of Drosophila. Development 130:1537-1547. (Pubitemid 36527515)
21. Hersh BM, Carroll SB (2005) Direct regulation of knot gene expression by Ultrabithorax and the evolution of cis-regulatory elements in Drosophila. Development 132: 1567-1577. (Pubitemid 40575858)
22. Pallavi SK, Kannan R, Shashidhara LS (2006) Negative regulation of Egfr/Ras pathway by Ultrabithorax during haltere development in Drosophila. Dev Biol 296:340-352. (Pubitemid 44189343)
23. de Navas LF, Garaulet DL, Sánchez-Herrero E (2006) The ultrabithorax Hox gene of Drosophila controls haltere size by regulating the Dpp pathway. Development 133: 4495-4506. (Pubitemid 46017824)
24. Crickmore MA, Mann RS (2007) Hox control of morphogen mobility and organ development through regulation of glypican expression. Development 134:327-334.
25. Makhijani K, Kalyani C, Srividya T, Shashidhara LS (2007) Modulation of Decapentaplegic gradient during haltere specification in Drosophila. Dev Biol 302:243-255. (Pubitemid 46096939)
26. Mohit P, et al. (2006) Modulation of AP and DV signaling pathways by the homeotic gene Ultrabithorax during haltere development in Drosophila. Dev Biol 291:356-367.
27. Hersh BM, et al. (2007) The UBX-regulated network in the haltere imaginal disc of D. melanogaster. Dev Biol 302:717-727. (Pubitemid 46216281)
28. McGuire SE, Le PT, Osborn AJ, Matsumoto K, Davis RL (2003) Spatiotemporal rescue of memory dysfunction in Drosophila. Science 302:1765-1768. (Pubitemid 37505740)
29. Tour E, Hittinger CT, McGinnis W (2005) Evolutionarily conserved domains required for activation and repression functions of the Drosophila Hox protein Ultrabithorax. Development 132:5271-5281. (Pubitemid 43020181)
30. Lovegrove B, et al. (2006) Coordinated control of cell adhesion, polarity, and cytoskeleton underlies Hox-induced organogenesis in Drosophila. Curr Biol 16: 2206-2216. (Pubitemid 44739277)
31. Butler MJ, et al. (2003) Discovery of genes with highly restricted expression patterns in the Drosophila wing disc using DNA oligonucleotide microarrays. Development 130: 659-670. (Pubitemid 36240576)
32. Molnar C, López-Varea A, Hernández R, de Celis JF (2006) A gain-of-function screen identifying genes required for vein formation in the Drosophila melanogaster wing. Genetics 174:1635-1659. (Pubitemid 44808329)
33. Walsh CM, Carroll SB (2007) Collaboration between Smads and a Hox protein in target gene repression. Development 134:3585-3592. (Pubitemid 350104369)
34. Peterson BK, et al. (2009) Big genomes facilitate the comparative identification of regulatory elements. PLoS ONE 4:e4688.