Leukocyte-mediated cell dissemination and metastasis: Findings from multiple types of human tumors

Journal of Cellular Biochemistry

Volumn 112, Issue 4, 2011, Pages 1154-1167

  Man, Yan Gao ^a   Mason, Jeffrey ^a   Harley, Russell ^a   Kim, Yeon Ho ^b   Zhu, Kangmin ^c   Gardner, William A ^a  

^a ARMED FORCES INSTITUTE OF PATHOLOGY   (United States)

^b WALTER REED ARMY MEDICAL CENTER   (United States)

^c Uniformed Services University of the Health Sciences   (United States)

Author keywords

Intercellular junctions; Leukocytes; Lymphocytes; Surface adhesion molecules; Tumor invasion; Tumor metastasis; Tumor stem cell

Indexed keywords

BETA CATENIN; HERMES ANTIGEN; UVOMORULIN;

ARTICLE; BREAST CANCER; CANCER INVASION; CELL JUNCTION; CELL MEMBRANE; CELL MOTION; CELL PROLIFERATION; CELL STRUCTURE; FEMALE; HUMAN; HUMAN CELL; LEUKOCYTE; LEUKOCYTE AGGREGATION; LEUKOCYTE MIGRATION; LUNG CANCER; MALE; METASTASIS; PRIORITY JOURNAL; PROSTATE CANCER; TUMOR CELL; UTERINE CERVIX CANCER;

ANTIGENS, CD34; BREAST NEOPLASMS; COLLAGEN TYPE IV; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; KERATINS; KI-67 ANTIGEN; LEUKOCYTES; MALE; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; PROSTATIC NEOPLASMS; TUMOR SUPPRESSOR PROTEIN P53; UTERINE CERVICAL NEOPLASMS;

EID: 79952570813     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.23035     Document Type: Article

References (40)

1. Bari R, Zhang YH, Zhang F, Wang NX, Stipp CS, Zheng JJ, Zhang XA. 2009. Transmembrane interactions are needed for KAI1/CD82-mediated suppression of cancer invasion and metastasis. Am J Pathol 174:647-660.
2. Christofori G. 2006. New signals from the invasive front. Nature 441(7092):444-450. (Pubitemid 44050139)
3. De Baetselier P, Roos E, Brys L, Remets L, Feldman M. 1984. Generation of invasive and metastatic variants of a non-metastatic T-cell lymphoma by in vivo fusion with normal host cells. Int J Cancer 34(5):731-738. (Pubitemid 15207017)
4. DeNarddo DG, Johansson M, Coussens LM. 2008. Immune cells as mediators of solid tumor metastasis. Cancer Metastasis Rev 27(1):11-18.
5. Fidler IJ, Kripke M. 1977. Metastasis results from preexisting variant cells within a malignant tumor. Science 197:893-895. (Pubitemid 8168759)
6. Gannot G, Gannot I, Vered H, Buchner A, Keisaris Y. 2002. Increase in immune cell infiltration with progression of oral epithelium from hyperkeratosis to dysplasia and carcinoma. Br J Cancer 86:1444-1448. (Pubitemid 34548068)
7. Hu M, Yao J, Caroll DK, Weremowicz S, Chen H, Carrasco D, Richardson A, Violette S, Nikolskaya T, Nikolsky Y, Bauerlein EL, Hahn WC, Gelman RS, Allred C, Bissell MJ, Schnitt S, Polyak K. 2008. Regulation of in situ to invasive breast carcinoma transition. Cancer Cell 13:394-406. (Pubitemid 351609443)
8. Hunter KW, Crawford NP, Alsarraj J. 2008. Mechanisms of metastasis. Breast Cancer Res 10(Suppl 1):S2.
9. Li F, Tiede B, Massague J, Kang Y. 2007. Beyond tumorigenesis: Cancer stem cells in metastasis. Cell Res 17:3-14. (Pubitemid 46096419)
10. Lima LG, Chammas R, Monteiro RQ, Moreira ME, Barcinski MA. 2009. Tumor-derived microvesicles modulate the establishment of metastatic melanoma in a phosphatidylserine-dependent manner. Cancer Lett 283(2):168-175.
11. MacLennan GT, Eisenberg R, Fleshman RL, Taylor JM, Fu P, Resnick MI, Gupta S. 2006. The influence of chronic inflammation in prostatic carcinogenesis: A 5-year follow-up study. J Urol 176:1012-1016. (Pubitemid 44142579)
12. Man YG. 2007. Focal degeneration of aged or injured myoepithelial cells and the resultant auto-immunoreactions are trigger factors for breast tumor invasion. Med Hypotheses 69(6):1340-1357.
13. Man YG. 2010. Aberrant leukocyte infiltration: A direct trigger for breast tumor invasion and metastasis. Int J Biol Sci 6(2):129-132.
14. Man YG, Burgar A. 2003. An antigen unmasking protocol that satisfies both immunohistochemical and subsequent molecular biological assessments. Pathol Res Pract 199:815-825. (Pubitemid 38239875)
15. Man YG, Gardner WA. 2008. Focal degeneration of basal cells and the resultant auto-immunoreactions: A novel mechanism for prostate tumor progression and invasion. Med Hypotheses 70:387-408. (Pubitemid 350297590)
16. Man YG, Tai L, Barner R, Vang R, Saenger JS, Shekitka KM, Bratthauer GL, Wheeler DT, Liang CL, Vinh TN, Strauss BL. 2003. Cell clusters overlying focally disrupted mammary myoepithelial cell layers and adjacent cells within the same duct display different immuno-histochemical and genetic features: Implications for tumor progression and invasion. Breast Cancer Res 5:R231-R241.
17. Man YG, Zhang Y, Shen T, Vinh TN, Zeng X, Tauler J, Mulshine JL, Strauss BL. 2005. cDNA expression profiling identifies elevated expressions of tumor progression and invasion related genes in cell clusters of in situ breast tumors. Breast Cancer Res Treat 89:199-208. (Pubitemid 40249054)
18. Man YG, Shen T, Zhao YG, Sang QX. 2005. Focal prostate basal cell layer disruptions and leukocyte infiltration are correlated events: A potential mechanism for basal cell layer disruptions and tumor invasion. Cancer Detect Prev 29:161-169.
19. Man YG, Zhao CQ, Wang J. 2006. Breast tumor cell clusters and their budding derivatives show different immunohistochemical profiles during stromal invasion: Implications for hormonal and drug therapies. Cancer Ther 4:193-204.
20. Mathelin C, Annane K, Treisser A, Chenard MP, Tomasetto C, Bellocq JP, Rio MC. 2008. Pregnancy and post-partum breast cancer: A prospective study. Anticancer Res 28(4C):2447-2452.
21. Nakshatri H, Srour EF, Badve S. 2009. Breast cancer stem cells and intrinsic subtypes: Controversies rage on. Curr Stem Cell Res Ther 4(1):50-60.
22. Nguyen DX, Massagué J. 2007. Genetic determination of cancer metastasis. Nat Rev Cancer 8:341-352.
23. O'Brien JO, Lyons T, Bell KP, Monks J, Lucia S, Wilson RS, Hines L, Man YG, Borges V, Schedin P. 2010. Alternatively activated macrophages and collagen I remodeling characterize the post partum involuting mammary gland across species. Am J Pathol 176(3):1241-1255.
24. Pawelek JM, Chakraborty AK. 2008. The cancer cell-leukocyte fusion theory of metastasis. Adv Cancer Res 101:397-444.
25. Pawley JB. 2006. Foundations of confocal scanned imaging in light microscopy. In: Fawley JB, editor. Handbook of biological confocal microscopy. Shinya Inoue, Berlin: Springer. pp 1-19.
26. Pentheroudakis G, Briasoulis E, Pavlidis N. 2007. Cancer of unknown primary site: Missing primary or missing biology? Oncologist 12(4):418-425.
27. Phillips TM, Kim K, Vlashi E, McBride WH, Pajonk F. 2007. Effects of recombinant erythropoietin on breast cancer-initiating cells. Neoplasia 9(12):1122-1129. (Pubitemid 350255350)
28. Pollard JW. 2004. Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer 4(1):71-78. (Pubitemid 38082155)
29. Polyak K, Weinberg RA. 2009. Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits. Nat Rev Cancer 9(4):265-273.
30. Pratap J, Wixted JJ, Gaur T, Zaidi SK, Dobson J, Gokul KD, Hussain S, van Wijnen AJ, Stein JL, Stein GS, Lian JB. 2008. Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells. Cancer Res 68(19):7795-7802.
31. Pratap J, Imbalzano KM, Underwood JM, Cohet N, Gokul K, Akech J, van Wijnen AJ, Stein JL, Imbalzano AN, Nickerson JA, Lian JB, Stein GS. 2009. Ectopic runx2 expression in mammary epithelial cells disrupts formation of normal acini structure: Implications for breast cancer progression. Cancer Res 69(17):6807-6814.
32. Rodriguez AO, Chew H, Cress R, Cress R, Xing G, McElvy S, Danielsen B, Smith L. 2008. Evidence of poorer survival in pregnancy-associated breast cancer. Obstet Gynecol 112(1):71-78.
33. Smith CJ, Gardner WA, Jr. 1987. Inflammation-proliferation: Possible relationships in the prostate. Prog Clin Biol Res 239:317-325.
34. Talmadge JE, Wolman SR, Fidler IJ. 1982. Evidence for the clonal origin of spontaneous metastases. Science 217:361-363. (Pubitemid 12090734)
35. Tavassoli FA, Man YG. 1995. Morphofunctional features of intraductal hyperplasia, atypical hyperplasia, and various grades of intraductal carcinoma. Breast J 1(3):155-162.
36. Vignery A. 2006. Macrophage fusion: Are somatic and cancer cells possible partners? Trends Cell Biol 15(4):188-193.
37. Wyckoff J, Wang W, Lin EY, Wang Y, Pixley F, Stanley ER, Graf T, Pollard JW, Segall J, Condeelis J. 2004. A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors. Cancer Res 64(19):7022-7029. (Pubitemid 39331012)
38. Wyckoff JB, Wang Y, Lin EY, Li JF, Goswami S, Stanley ER, Segall JE, Pollard JW, Condeelis J. 2007. Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors. Cancer Res 67(6):2649-2656. (Pubitemid 46548952)
39. Wysoczynski M, Ratajczak MZ. 2009. Lung cancer secreted microvesicles: Underappreciated modulators of microenvironment in expanding tumors. Int J Cancer 125(7):1595-1603.
40. Yousefi M, Mattu R, Gao C, Mans YG. 2005. Mammary ducts with and without focal myoepithelial cell layer disruptions show a different frequency of white blood cell infiltration and growth pattern: Implications for tumor progression and invasion. Appl Immunohistochem Mol Morphol 13:30-37. (Pubitemid 40283800)