Myelin down-regulates myelin phagocytosis by microglia and macrophages through interactions between CD47 on myelin and SIRPα (signal regulatory protein-α) on phagocytes

Journal of Neuroinflammation

Volumn 8, Issue , 2011, Pages

  Gitik, Miri ^a   Liraz Zaltsman, Sigal ^a   Oldenborg, Per Arne ^b   Reichert, Fanny ^a   Rotshenker, Shlomo ^a  

^a HEBREW UNIVERSITY   (Israel)

^b UMEÅ UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CD47 ANTIGEN; GLYCOPROTEIN; MYELIN; SHORT HAIRPIN RNA; SIGNAL REGULATORY PROTEIN ALPHA; UNCLASSIFIED DRUG; IMMUNOGLOBULIN RECEPTOR; PTPNS1 PROTEIN, MOUSE; SIRPALPHA PROTEIN, RAT;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CULTURE MEDIUM; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOFLUORESCENCE MICROSCOPY; LENTIVIRUS INFECTION; MACROPHAGE; MICROGLIA; MOUSE; NEWBORN; NONHUMAN; OLIGODENDROGLIA; PHAGOCYTE; PHAGOCYTOSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INTERACTION; RAT; SCHWANN CELL; ANIMAL; BAGG ALBINO MOUSE; CELL CULTURE; CYTOLOGY; FIBROBLAST; GENETICS; METABOLISM; MOUSE MUTANT; MYELIN SHEATH; NERVE DEGENERATION; NERVE FIBER; PATHOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIGENS, CD47; AXONS; CELLS, CULTURED; DOWN-REGULATION; FIBROBLASTS; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; MICROGLIA; MYELIN SHEATH; NERVE DEGENERATION; PHAGOCYTOSIS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, IMMUNOLOGIC; SCHWANN CELLS; WALLERIAN DEGENERATION;

EID: 79952545687     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-8-24     Document Type: Article

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