Distinct inflammatory stimuli induce different patterns of myelin phagocytosis and degradation in recruited macrophages

Experimental Neurology

Volumn 167, Issue 2, 2001, Pages 401-409

  Slobodov, Uri ^a   Reichert, Fanny ^a   Mirski, Roni ^a   Rotshenker, Shlomo ^a  

^a HEBREW UNIVERSITY   (Israel)

Author keywords

CR3 MAC 1; EAE; Macrophage; Microglia; Myelin; Nerve injury; Nerve regeneration; Phagocytosis

Indexed keywords

MYELIN BASIC PROTEIN; PEPTONE; THIOGLYCOLIC ACID DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DEMYELINATING DISEASE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MACROPHAGE ACTIVATION; MICROGLIA; MOUSE; MYELIN SHEATH; NONHUMAN; PATHOPHYSIOLOGY; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; STIMULUS RESPONSE;

EID: 0035134433     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.2000.7559     Document Type: Article

References (22)

1. Central neuron-glial and glial-glial interactions following axon injury
2. F4/80, a monoclonal antibody directed specifically against the mouse macrophage
3. The cytokine network of wallerian degeneration: IL-10 and GMCSF
4. Anti-macrophage CR3 antibody blocks myelin phagocytosis by macrophages in vitro
5. Monoclonal antibodies that recognize distinct epitopes of the macrophage type three complement receptor differ in their ability to inhibit binding of Leishmania promastigotes harvested at different phases of their growth cycle
6. The I domain is a major recognition site on the leukocyte integrin Mac-1 (CD11b/CD18) for four distinct adhesion ligands
7. Membrane molecules as differentiation antigens of murine macrophages
8. Myelin formation, structure, and metabolism
9. Receptor-mediated phagocytosis of myelin by macrophages and microglia: Effect of opsonization and receptor blocking agents
10. Myelination in rat brain: Changes in myelin composition during brain maturation
11. Deficient activation of microglia during optic nerve degeneration
12. Galectin-3/MAC-2 in experimental allergic encephalomyelitis
13. Peripheral nerve injury induces Schwann cells to express two macrophage phenotypes: Phagocytosis and the galactose-specific lectin MAC-2
14. Resident microglia and hematogenous macrophages as phagocytes in adoptively transferred experimental autoimmune encephalomyelitis: An investigation using rat radiation bone marrow chimeras
15. Monoclonal antibody to the murine type 3 complement receptor inhibits adhesion of myelomonocytic cells in vitro and inflammatory cell recruitment in vivo
16. Phagocytosis of myelin by microglia in vitro
17. Phagocytosis of myelin in demyelinative disease: A review
18. Macrophage and microglial responses to cytokines in vitro: Phagocytic activity, proteolytic enzyme release, and free radical production
19. The role of microglia and macrophages in the pathophysiology of the CNS
20. Antigens associated with the activation of murine mononuclear phagocytes in vivo: Differential expression of lymphocyte function-associated antigen in the several stages of development
21. Macrophage phagocytosis of myelin in vitro determined by flow cytometry: Phagocytosis is mediated by CR3 and induces production of tumor necrosis factor-alpha and nitric oxide
22. Animal models