Multiphoton microscopy of engineered dermal substitutes: Assessment of 3-D collagen matrix remodeling induced by fibroblast contraction

Journal of Biomedical Optics

Volumn 15, Issue 5, 2010, Pages

  Pena, Ana Maria ^a   Fagot, Dominique ^a   Olive, Christian ^a   Michelet, Jean François ^a   Galey, Jean Baptiste ^a   Leroy, Frédéric ^a   Beaurepaire, Emmanuel ^b,c   Martin, Jean Louis ^b,c   Colonna, Anne ^a   Schanne Klein, Marie Claire ^b,c  

^a L ORÉAL RECHERCHE   (France)

^b LABORATOIRE D OPTIQUE ET BIOSCIENCES   (France)

^c INSERM   (France)

Author keywords

Collagen; Dermal substitutes; Fibroblasts; Multiphoton microscopy; Second harmonic generation; Three dimensional imaging

Indexed keywords

ANTI-AGING; COLLAGEN FIBRILS; COLLAGEN MATRICES; DERMAL FIBROBLASTS; DERMAL SUBSTITUTES; DERMAL TISSUES; EXTRACELLULAR MATRICES; FIBRILLAR COLLAGENS; IN-CONTROL; IN-SITU; INHIBITORY EFFECT; MECHANICAL FORCE; MULTI-PHOTON MICROSCOPY; THREE DIMENSIONAL IMAGING; TWO-PHOTON EXCITED FLUORESCENCE;

CELL CULTURE; CHROMOPHORES; ENZYME INHIBITION; FIBROBLASTS; HARMONIC GENERATION; THREE DIMENSIONAL; TISSUE;

COLLAGEN;

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; AMIDE; ENZYME INHIBITOR; FIBRILLAR COLLAGEN; PYRIDINE DERIVATIVE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA PROTEIN, HUMAN;

ARTICLE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; EXTRACELLULAR MATRIX; FIBROBLAST; HUMAN; IN VITRO STUDY; LIGHT RELATED PHENOMENA; METABOLISM; METHODOLOGY; MULTIPHOTON MICROSCOPY; SKIN; THREE DIMENSIONAL IMAGING; TISSUE ENGINEERING; ULTRASTRUCTURE;

AMIDES; ENZYME INHIBITORS; EXTRACELLULAR MATRIX; FIBRILLAR COLLAGENS; FIBROBLASTS; HUMANS; IMAGING, THREE-DIMENSIONAL; MICROSCOPY, FLUORESCENCE, MULTIPHOTON; OPTICAL PHENOMENA; PYRIDINES; RHOA GTP-BINDING PROTEIN; SKIN; TISSUE ENGINEERING;

EID: 79952522066     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.3503411     Document Type: Article

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