Neuroprotective effects of CIC-3 chloride channel in glutamate-induced retinal ganglion cell RGC-5 apoptosis

Neural Regeneration Research

Volumn 6, Issue 6, 2011, Pages 450-456

  Yu, Li ^a   Han, Ning ^a   Jiang, Ligang ^b   Zheng, Yajuan ^a   Liu, Lifeng ^c  

^a THE SECOND HOSPITAL OF JILIN UNIVERSITY   (China)

^b Affiliated Jilin Hospital of Jilin University   (China)

^c BEIHUA UNIVERSITY   (China)

Author keywords

Apoptosis; CIC 3; Neuroprotection; Retinal ganglion cells; Smads; Transforming growth factor

Indexed keywords

CHLORIDE CHANNEL; CHLORIDE CHANNEL 3; GLUTAMIC ACID; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA2; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL SURVIVAL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; NEUROPROTECTION; PROTEIN EXPRESSION; RETINA GANGLION CELL; SIGNAL TRANSDUCTION; SURVIVAL RATE;

EID: 79952470082     PISSN: 16735374     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Varma R, Peeples P, Walt JG, et al. Disease progression and the need for neuroprotection in glaucoma management. Am J Manage Care. 2008; 14(1 Suppl):S15-19.
2. Nickells RW. Ganglion cell death in glaucoma: from mice to men. Vet Ohthalmol. 2007; Suppl 1:88-94.
3. Levin LA. Neuroprotection and regeneration in glaucoma. Ophthalmol Clin North Am. 2005; 18(4):585-596.
4. Fan W, Agarwal N, Kumar MD, et al. Retinal ganglion cell death and neuroprotection: Involvement of the CaMKIIα gene. Brain Res Mol Brain Res. 2005; 139(2):306-316.
5. Kumar DM, Perez E, Cai Z Y, et al. Role of nonfeminizing estrogen analogues in neuroprotection of rat retinal ganglion cells against glutamate-induced cytotoxicity. Free Radic Biol Med. 2005; 38(9):1152-1163.
6. Sucher NJ, Lipton SA, Dreyer EB. Molecular basis of glutamate toxicity in retinal ganglion cells. Vision Res. 1997; 37(24): 3483-3493.
7. Cheng G, Shao Z, Chaudhari B. Involvement of chloride channels in TGF-beta1-induced apoptosis of human bronchial epithelial cells. Physiol Lung Cell Mol Physiol. 2007; 293(5):L1339-1347.
8. Heldin CH, Landström M, Moustakas A. Mechanism of TGF-beta signaling to growth arrest,apoptosis,and epithelial-mesenchymal transition. Curr Opin Cell Biol. 2009; 1(2):166-176.
9. Tang YB, Liu YJ, Zhou JG, et al. Silence of ClC-3 chloride channel inhibits cell proliferation and the cell cycle via G/S phase arrest in rat basilar arterial smooth muscle cells. Cell Prolif. 2008; 41(15): 775-785.
10. Schmieder S, Lindenthal S, Ehrenfeld J. Tissue-specific N-glycosylation of the ClC-3 chloride channel. Biochem Biophys Res Commun. 2001; 286(3):635-640.
11. Duan D, Winterm C, Cowley S, et al. Molecular identification of a volume-regulated chloride channel. Nature. 1997; 390(6658): 417-421.
12. Szabo I, Lepple-Wienhues A, Kaba KN, et al. Tyrosine kinase-dependent activation of a chloride channel in CD2952induced apoptosis in T lymphocytes. Proc Natl Acad Sci U S A. 1998; 95(11):6169-6174.
13. Souktani R, Ghaleh B, Tissier R, et al. Inhibitors of swelling-activated chloride channels increase infarct size and apoptosis in rabbit myocardium. Fundam Clin Pharmacol. 2003; 17(5):555-561.
14. Wei L, Xiao AY, Jin C, et al. Effects of chloride and potassium channel blockers on apoptotic cell shrinkage and apoptosis in cortical neurons. Pflugers Arch. 2004; 448(3):325-334.
15. Lemonnier L, Lazarenko R, Shuba Y, et al. Alterations in the regulatory volume decrease (RVD) and swelling-activated Cl-current associated with neuroendocrine defferentiation of prostate cancer epithelial cells. Endocr Relat Cancer. 2005; 12(2): 335-349.
16. Lemonnier L, Shuba Y, Crepin A, et al. Bcl-2-dependent modulation of swelling-activated Cl current and CLC-3 expression in human prostate cancer epithelial cells. Cancer Res. 2004; 64(14):4841-4848.
17. Dai YP, Bongalon S, Hatton WJ, et al. ClC-3 chloride channel is upregulated by hypertrophy and inflammation in rat and canine pulmonary artery. Br J Pharmacol. 2005; 145(1):5-14.
18. Jiao JD, Xu CQ, Yue P, et al. Volume-sensitive outwardly rectifying chloride channels are involved in oxidative stress-induced apoptosis of mesangial cells. Biochem Biophys Res Commun. 2006; 340(1):277-285.
19. Claud EC, Lu J, Wang XQ, et al. Platelet-activating factor-induced chloride channel activation is associated with intracellular acidosis and apoptosis of intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2008; 294(5):G1191-1200.
20. Wang G, Long J, Matsuura I, et al. The Smad3 linker region contains a transcriptional activation domain. Bioehem J. 2005; 386(Pt 1):29-34.
21. Zhang Y, Chang C, Gehling DJ, et al. Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase. Proc Natl Acad Sci U S A. 2001; 98(3):974-979.
22. Euler-Taimor G, Heger J. The complex pattern of SMAD signaling in the cardiovascular system. Cardiovasc Res. 2006; 69(1):15-25.
23. Shih WL, Liao MH, Lin PY, et al. PI 3-kinase/Akt and STAT3 are required for the prevention of TGF-β-induced Hep3B cell apoptosis by autocrine motility factor/phosphoglucose isomerase. Cancer Lett. 2010; 290(2):223-237.
24. Gramley F, Lorenzen J, Koellensperger E, et al. Atrial fibrosis and atrial fibrillation: the role of the TGF-β1 signaling pathway. Int J Cardiol. 2010; 143(3):405-413.
25. Ki KD, Tong S Y, Huh CY, et al. Expression and mutational analysis of TGF-β/Smads signaling in human cervical cancers. J Gynecol Oncol. 2009; 20(2):117-121.
26. Tian M, Neil JR, Schiemann W P. Transforming growth factor-β and the hallmarks of cancer. Cell Signal. 2010.
27. Jobling AI, Wan R, Gentle A, et al. Retinal and choroidal TGF-beta in the tree shrew model of myopia: isoform expression, activation and effects on function. Exp Eye Res. 2009; 88(3):458-466.
28. Tripathi RC, Li J, Borisuth NS, et al. Trabecular cells of the eye express messenger RNA for transforming growth factor-beta 1 and secrete this cytokine. Invest Ophthalmol Vis Sci. 1993; 34(8):2562-2569.
29. Ymamoto N, Itonaga K, Marunouchi T, et al. Concentration of trasforming growth factor beta2 in aqueous humor. Opthalmic Res. 2005; 37(1):29-33.
30. Enz R, Ross BJ, Cutting GR. Expression of the voltage-gated chloride channel ClC-2 in rod bipolar cells of the rat retina. J Neurosci.1999; 19(22):9841-9847.