Synthesis of 2,2-disubstituted azaindolines by intramolecular cyclization in acidic media

Synlett

Volumn , Issue 5, 2011, Pages 684-688

  Métro, Thomas Xavier ^a   Fayet, Christine ^a   Arnaud, Florian ^a   Rameix, Nathalie ^a   Fraisse, Pierre ^a   Janody, Simon ^a   Sevrin, Mireille ^a   George, Pascal ^a   Vogel, Rachel ^a  

^a SANOFI   (France)

Author keywords

azaindolines; cyclization; nucleophilic addition; pyridines; spiro compounds

Indexed keywords

2,2 DISUBSTITUTED AZAINDOLINE DERIVATIVE; ALCOHOL; ALKENE; AMINOPYRIDINE; INDOLE DERIVATIVE; UNCLASSIFIED DRUG;

ACIDITY; ARTICLE; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; CYCLIZATION; INTRAMOLECULAR CYCLIZATION; MOLECULAR INTERACTION; NUCLEOPHILICITY; SUBSTITUTION REACTION; SYNTHESIS;

EID: 79952444479     PISSN: 09365214     EISSN: 14372096     Source Type: Journal    
DOI: 10.1055/s-0030-1259678     Document Type: Article

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