Hexahydro-β-acids induce apoptosis through mitochondrial pathway, GADD153 expression, and caspase activation in human leukemia cells

Food and Chemical Toxicology

Volumn 49, Issue 4, 2011, Pages 1033-1042

  Liu, Cheng Bin ^a,b   Chen, Li Hua ^a,b   Cheng, An Chin ^c   Chen, Wei Jen ^d   Tsai, Mei Ling ^a   Liu, Yumei ^e   Ho, Chi Tang ^f   Pan, Min Hsiung ^a  

^a NATIONAL KAOHSIUNG UNIVERSITY OF APPLIED SCIENCES   (Taiwan)

^b KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^c CHANG JUNG CHRISTIAN UNIVERSITY   (Taiwan)

^d CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^e XINJIANG UNIVERSITY   (China)

^f RUTGERS UNIVERSITY   (United States)

Author keywords

acids; Apoptosis; Caspase 9; Cytochrome c; Hexahydro acids; Mitochondrial pathway

Indexed keywords

ADLUPULONE; BETA ACID; BETA ACTIN; CASPASE 9; COLUPULON; CYTOCHROME C; DNA; FAS ANTIGEN; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HEXAHYDRO BETA ACID; HEXAHYDRO N LUPULONE; HEXAHYDROADLUPULONE; HEXAHYDROCOLUPULONE; N LUPULONE; PLANT MEDICINAL PRODUCT; PROCASPASE 8; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN BID; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL STRAIN HL 60; CELL STRUCTURE; CHROMATIN CONDENSATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; DNA FRAGMENTATION; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME RELEASE; GENE ACTIVATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; OXIDATION; PROMYELOCYTIC LEUKEMIA; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; SINGLE STRANDED DNA BREAK; UPREGULATION;

ACIDS; APOPTOSIS; CASPASES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA DAMAGE; ENZYME ACTIVATION; HL-60 CELLS; HUMANS; LEUKEMIA; MITOCHONDRIA; TRANSCRIPTION FACTOR CHOP;

EID: 79952441943     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2011.01.016     Document Type: Article

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