Proteomic characterization and functional analysis of outer membrane vesicles of Francisella novicida suggests possible role in virulence and use as a vaccine

Journal of Proteome Research

Volumn 10, Issue 3, 2011, Pages 954-967

  Pierson, Tony ^a   Matrakas, Demetrios ^a   Taylor, Yuka U ^a   Manyam, Ganiraju ^b   Morozov, Victor N ^a,c   Zhou, Weidong ^a   Van Hoek, Monique L ^a,c  

^a GEORGE MASON UNIVERSITY   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c INSTITUTE OF THEORETICAL AND EXPERIMENTAL BIOPHYSICS   (Russian Federation)

Author keywords

Francisella; membrane; OMV; tularemia; vaccine; vesicle; virulence

Indexed keywords

ACID PHOSPHATASE; BACTERIAL VACCINE; PROTEOME;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATOMIC FORCE MICROSCOPY; BACTERIAL VIRULENCE; BACTERIUM ISOLATE; BIOCHEMISTRY; CELL CULTURE; CELL VACUOLE; CONTROLLED STUDY; CYTOTOXICITY; FRANCISELLA; FRANCISELLA NOVICIDA; FRANCISELLA PHILOMIRAGIA; FRANCISELLA TULARENSIS; HEMOLYSIS; HOST CELL; HOST PARASITE INTERACTION; IMMUNITY; LIQUID CHROMATOGRAPHY; MACROPHAGE; MASS SPECTROMETRY; MOUSE; NONHUMAN; OUTER MEMBRANE VESICLE; PATHOGENICITY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEOMICS; TRANSMISSION ELECTRON MICROSCOPY; VACCINATION;

ANIMALS; BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL VACCINES; CELL LINE; CELL MEMBRANE; COMPUTATIONAL BIOLOGY; FRANCISELLA; HUMANS; MICE; MICE, INBRED BALB C; PROTEOME;

FRANCISELLA; FRANCISELLA PHILOMIRAGIA; FRANCISELLA TULARENSIS; FRANCISELLA TULARENSIS SUBSP. NOVICIDA; MURINAE; MUS; NEISSERIA MENINGITIDIS; OAT MOSAIC VIRUS;

EID: 79952418804     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr1009756     Document Type: Article

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