From tumor immunology to cancer immunotherapy: Miles to go

Journal of Cancer Research and Therapeutics

Volumn 6, Issue 4, 2010, Pages 427-431

  Tiwari, Manjul ^a  

^a SHARDA UNIVERSITY   (India)

Author keywords

DNA microarray; immune mediated tumors; microarray; tumor immunology

Indexed keywords

CANCER VACCINE; DENDRITIC CELL VACCINE; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 4; TUMOR VACCINE;

ANTIGEN PRESENTING CELL; ANTIGEN RECOGNITION; CANCER CELL; CANCER IMMUNOTHERAPY; CELL KILLING; COMPARATIVE GENOMIC HYBRIDIZATION; CYTOLOGY; CYTOTOXICITY; DENDRITIC CELL; DIFFERENTIAL DISPLAY; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENOME; HIGH THROUGHPUT SCREENING; HUMAN; IMMUNE RESPONSE; IMMUNE SYSTEM; INFORMATION; LYMPHOCYTE; LYMPHOCYTE SUBPOPULATION; MICROARRAY ANALYSIS; NEOPLASM; NONHUMAN; PROTEIN PROCESSING; RADIATION DOSE; REVIEW; TUMOR IMMUNITY; TUMOR IMMUNOLOGY; TUMOR MICROENVIRONMENT; TUMOR SUPPRESSOR GENE;

DENDRITIC CELLS; GENOME, HUMAN; HUMANS; NEOPLASMS;

EID: 79952416703     PISSN: 09731482     EISSN: 19984138     Source Type: Journal    
DOI: 10.4103/0973-1482.77071     Document Type: Review

References (51)

1. Pardoll DM. Spinning molecular immunology into successful immunotherapy. Nat Rev Immunol 2002;2:227-38. (Pubitemid 37323223)
2. Mocellin S, Mandruzzato S, Bronte V. Part I: Vaccines for solid tumours. Lancet Oncol 2004;5:681-9. (Pubitemid 40267853)
3. Mocellin S, Semenzato G, Mandruzzato S. Part II: Vaccines for haematological malignant disorders. Lancet Oncol 2004;5:727-37. (Pubitemid 39646782)
4. Rosenberg SA. Progress in human tumour immunology and immunotherapy. Nature 2001;411:380-4. (Pubitemid 32467048)
5. Pinkel D, Segraves R, Sudar D. High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays. Nat Genet 1998;20:207-11. (Pubitemid 28455458)
6. Broude NE. Differential display in the time of microarrays. Expert Rev Mol Diagn 2002;2:209-16. (Pubitemid 34662812)
7. Velculescu VE, Zhang L, Vogelstein B. Serial analysis of gene expression. Science 1995;270:484-7.
8. Brown PO, Botstein D. Exploring the new world of the genome with DNA microarrays. Nat Genet 1999;21:33-7. (Pubitemid 29031489)
9. Goldenfeld N, Kadanoff L P. Simple lessons from complexity. Science 1999;284:87-9. (Pubitemid 29282050)
10. Staudt LM, Brown PO. Genomic views of the immune system. Annu Rev Immunol 2000;18:829-59. (Pubitemid 30365399)
11. Ricciardi-Castagnoli P, Granucci F. Opinion: Interpretation of the complexity of innate immune responses by functional genomics. Nat Rev Immunol 2002;2:881-9.
12. Keil D, Luebke RW, Pruett SB. Quantifying the relationship between multiple immunological parameters and host resistance: Probing the limits of reductionism. J Immunol 2001;167:4543-52. (Pubitemid 32954333)
13. Mocellin S, Provenzano M, Rossi CR. DNA array-based gene profiling: From surgical specimen to the molecular portrait of cancer. Ann Surg 2005;241:16-26. (Pubitemid 40040989)
14. Kallioniemi O P, Wagner U, Kononen J. Tissue microarray technology for high-throughput molecular profiling of cancer. Hum Mol Genet 2001;10:657-62. (Pubitemid 32331572)
15. Le Naour F. Contribution of proteomics to tumor immunology. Proteomics 2001;1:1295-302.
16. Marincola FM, JafFee EM, Hicklin DJ. Escape of human solid tumors from T-cell recognition: Molecular mechanisms and functional significance. Adv Immunol 2000;74:181-273.
17. Toulouse A, Loubeau M, Morin J. RAR beta involvement in enhancement of lung tumor cell immunogenicity revealed by array analysis. FASEB J 2000;14:1224-32. (Pubitemid 30350404)
18. Mocellin S, Rossi CR, Nitti D. Cancer vaccine development: On the way to break immune tolerance to malignant cells. Exp Cell Res 2004;299:267-78. (Pubitemid 39179795)
19. Garnett CT, Palena C, Chakraborty M. Sublethal irradiation of human tumor cells modulates phenotype resulting in enhanced killing by cytotoxic T lymphocytes. Cancer Res 2004;64:7985-94. (Pubitemid 39446933)
20. Renkvist N, Castelli C, Robbins P F. A listing of human tumor antigens recognized by T cells. Cancer Immunol Immunother 2001;50:3-15. (Pubitemid 32250041)
21. Van der Bruggen P, Traversari C, Chomez P. A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma. Science 1991;254:1643-7. (Pubitemid 21917508)
22. Cox AL, Skipper J, Chen Y. Identification of a peptide recognized by five melanoma-specific human cytotoxic T cell lines. Science 1994;264:716-9. (Pubitemid 24185883)
23. Maecker B, von Bergwelt-Baildon, Anderson KS. Linking genomics to immunotherapy by reverse immunology-'immunomics' in the new millennium. Curr Mol Med 2001;1:609-19. (Pubitemid 33772039)
24. Young AN, Amin MB, Moreno CS. Expression profiling of renal epithelial neoplasms: A method for tumor classification and discovery of diagnostic molecular markers. Am J Pathol 2001;158:1639-51. (Pubitemid 32422929)
25. Takahashi M, Rhodes DR, Furge KA. Gene expression profiling of clear cell renal cell carcinoma: Gene identification and prognostic classification. Proc Nat l Acad Sci USA 2001;98:9754-9. (Pubitemid 32769376)
26. Boer JM, Huber WK, Sultmann H. Identification and classification of differentially expressed genes in renal cell carcinoma by expression profiling on a global human 31, 500-element cDNA array. Genome Res 2001;11:1861-70. (Pubitemid 33100427)
27. Shi YY, Wang HC, Yin YH. Identification and analysis of tumourassociated antigens in hepatocellular carcinoma. Br J Cancer 2005;92:929-34.
28. Yoshitake Y, Nakatsura T, Monji M. Proliferation potential-related protein, an ideal esophageal cancer antigen for immunotherapy, identified using complementary DNA microarray analysis. Clin Cancer Res 2004;10:6437-48. (Pubitemid 39346538)
29. Mathiassen S, Lauemoller SL, Ruhwald M. Tumor-associated antigens identified by mRNA expression profiling induce protective anti-tumor immunity. Eur J Immunol 2001;31:1239-46.
30. Wang T, Fan L, Watanabe Y. L552S, an alternatively spliced isoform of XAGE-1, is over-expressed in lung adenocarcinoma. Oncogene 2001;20:7699-709. (Pubitemid 33121943)
31. Weinschenk T, Gouttefangeas C, Schirle M. Integrated functional genomics approach for the design of patient-individual antitumor vaccines. Cancer Res 2002;62:5818-27. (Pubitemid 35204741)
32. Banchereau J, Briere F, Caux C. Immunobiology of dendritic cells. Annu Rev Immunol 2000;18:767-811. (Pubitemid 30365397)
33. Lanzavecchia A, Sallusto F. Regulation of T cell immunity by dendritic cells. Cell 2001;106:263-6. (Pubitemid 32772609)
34. Chen Z, Gordon JR, Zhang X. Analysis of the gene expression profiles of immature versus mature bone marrow-derived dendritic cells using DNA arrays. Biochem Biophys Res Commun 2002;290:66-72. (Pubitemid 34694465)
35. Suciu-Foca Cortesini N, Piazza F, Ho E. Distinct mRNA microarray profiles of tolerogenic dendritic cells. Hum Immunol 2001;62:1065-72. (Pubitemid 32971383)
36. Chen Z, Dehm S, Bonham K. DNA array and biological characterization of the impact of the maturation status of mouse dendritic cells on their phenotype and antitumor vaccination efficacy. Cell Immunol 2001;214:60-71. (Pubitemid 34280757)
37. Figdor CG, De Vries IJ, Lesterhuis WJ. Dendritic cell immunotherapy: Mapping the way. Nat Med 2004;10:475-80. (Pubitemid 38667904)
38. Ju XS, Hacker C, Madruga J. Towards determining the differentiation program of antigen-presenting dendritic cells by transcriptional profiling. Eur J Cell Biol 2003;82:75-86. (Pubitemid 36285043)
39. Huang H, Li F, Gordon JR. Synergistic enhancement of antitumor immunity with adoptively transferred tumor-specific CD4+ and CD8+ T cells and intratumoral lymphotactin transgene expression. Cancer Res 2002;62:2043-51. (Pubitemid 34408450)
40. Zhang X, Chen Z, Huang H. DNA microarray analysis of the gene expression profiles of naive versus activated tumor-specific T cells. Life Sci 2002;71:3005-17. (Pubitemid 35217877)
41. Carrabba MG, Castelli C, Maeurer MJ. Suboptimal activation of CD8 (+) T cells by melanoma-derived altered peptide ligands: Role of Melan-A/MART-1 optimized analogues. Cancer Res 2003;63:1560-7. (Pubitemid 36373644)
42. Verdeil G, Puthier D, Nguyen C. Gene profiling approach to establish the molecular bases for partial versus full activation of naive CD8 T lymphocytes. Ann NY Acad Sci 2002;975:68-76. (Pubitemid 36126952)
43. Keilholz U, Weber J, Finke JH. Immunologic monitoring of cancer vaccine therapy: Results of a workshop sponsored by the Society for Biological Therapy. J Immunother 2002;25:97-138. (Pubitemid 34260764)
44. Wang E, Marincola FM. A natural history of melanoma: Serial gene expression analysis. Immunol Today 2000;21:619-23. (Pubitemid 32044018)
45. Wang E, Miller LD, Ohnmacht GA. Prospective molecular profiling of melanoma metastases suggests classifiers of immune responsiveness. Cancer Res 2002;62:3581-6. (Pubitemid 34728828)
46. Mocellin S, Panelli MC, Wang E. The dual role of IL-10. Trends Immunol 2003;24:36-43. (Pubitemid 35462111)
47. Mocellin S, Panelli M, Wang E. IL-10 stimulatory effects on human NK cells explored by gene profile analysis. Genes Immun 2004;5:621-30. (Pubitemid 40045300)
48. Kelly JM, Darcy PK, Markby JL. Induction of tumor-specific T cell memory by NK cell-mediated tumor rejection. Nat Immunol 2002;3:83-90. (Pubitemid 34065622)
49. Mocellin S, Rossi C, Nitti D. Dissecting tumor responsiveness to immunotherapy: The experience of peptide-based melanoma vaccines. Biochim Biophys Acta Rev Cancer 2003;1653:61-71. (Pubitemid 37487648)
50. Rosenberg SA, Yang JC, Schwartzentruber DJ. Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma. Nat Med 1998;4:321-7. (Pubitemid 28144091)
51. Panelli MC, Wang E, Phan G, Puhlmann M, Miller L, Ohnmacht GA, et al. Gene-expression profiling of the response of peripheral blood mononuclear cells and melanoma metastases to systemic IL-2 administration. Genome Biol 2002;3: Reserach0035.