Glycosylphosphatidylinositol anchor-dependent stimulation pathway required for generation of baculovirus-derived recombinant scrapie prion protein

Journal of Virology

Volumn 85, Issue 6, 2011, Pages 2582-2588

  Imamura, Morikazu ^a   Kato, Nobuko ^a   Yoshioka, Miyako ^a   Okada, Hiroyuki ^a   Iwamaru, Yoshifumi ^a   Shimizu, Yoshihisa ^a   Mohri, Shirou ^a   Yokoyama, Takashi ^a   Murayama, Yuichi ^a  

^a NATIONAL INSTITUTE OF ANIMAL HEALTH   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; PRION PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BACULOVIRUS; CONTROLLED STUDY; DNA FRAGMENTATION; GENE AMPLIFICATION; GLYCOSYLATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN MODIFICATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; SCRAPIE; TISSUE HOMOGENATE;

ANIMALS; BACULOVIRIDAE; GENETIC VECTORS; GLYCOSYLPHOSPHATIDYLINOSITOLS; MICE; PRIONS; RECOMBINANT PROTEINS; SCRAPIE;

MUS; SCRAPIE PRION;

EID: 79952372174     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.02098-10     Document Type: Article

References (37)

1. Abid, K., R. Morales, and C. Soto. 2010. Cellular factors implicated in prion replication. FEBS Lett. 584:2409-2414.
2. Atarashi, R., et al. 2007. Ultrasensitive detection of scrapie prion protein using seeded conversion of recombinant prion protein. Nat. Methods 4:645-650. (Pubitemid 47202476)
3. Borchelt, D. R., M. Rogers, N. Stahl, G. Telling, and S. B. Prusiner. 1993. Release of the cellular prion protein from cultured cells after loss of its glycoinositol phospholipid anchor. Glycobiology 3:319-329.
4. Castilla, J., P. Saa, C. Hetz, and C. Soto. 2005. In vitro generation of infectious scrapie prions. Cell 121:195-206.
5. Castilla, J., P. Saa, and C. Soto. 2005. Detection of prions in blood. Nat. Med. 11:982-985.
6. Chesebro, B., et al. 2005. Anchorless prion protein results in infectious amyloid disease without clinical scrapie. Science 308:1435-1439. (Pubitemid 40791292)
7. Collinge, J. 2001. Prion diseases of humans and animals: their causes and molecular basis. Annu. Rev. Neurosci. 24:519-550.
8. Cordeiro, Y., et al. 2001. DNA converts cellular prion protein into the beta-sheet conformation and inhibits prion peptide aggregation. J. Biol. Chem. 276:49400-49409.
9. Davies, A., and B. P. Morgan. 1993. Expression of the glycosylphosphatidylinositol-linked complement-inhibiting protein CD59 antigen in insect cells using a baculovirus vector. Biochem. J. 295:889-896.
10. DebBurman, S. K., G. J. Raymond, B. Caughey, and S. Lindquist. 1997. Chaperone-supervised conversion of prion protein to its protease-resistant form. Proc. Natl. Acad. Sci. U. S. A. 94:13938-13943.
11. Deleault, N. R., B. T. Harris, J. R. Rees, and S. Supattapone. 2007. Formation of native prions from minimal components in vitro. Proc. Natl. Acad. Sci. U. S. A. 104:9741-9746. (Pubitemid 47175337)
12. Fraser, H., and A. G. Dickinson. 1968. The sequential development of the brain lesion of scrapie in three strains of mice. J. Comp. Pathol. 78:301-311.
13. Gonzalez-Romero, D., M. A. Barria, P. Leon, R. Morales, and C. Soto. 2008. Detection of infectious prions in urine. FEBS Lett. 582:3161-3166.
14. Grunewald, S., W. Haase, H. Reilander, and H. Michel. 1996. Glycosylation, palmitoylation, and localization of the human D2S receptor in baculovirus-infected insect cells. Biochemistry 35:15149-15161. (Pubitemid 26408846)
15. Hayashi, H., et al. 2004. Effect of tissue deterioration on postmortem BSE diagnosis by immunobiochemical detection of an abnormal isoform of prion protein. J. Vet. Med. Sci. 66:515-520.
16. Hsu, T. A., et al. 1997. Differential N-glycan patterns of secreted and intracellular IgG produced in Trichoplusia ni cells. J. Biol. Chem. 272:9062-9070.
17. Kazlauskaite, J., N. Sanghera, I. Sylvester, C. Venien-Bryan, and T. J. Pinheiro. 2003. Structural changes of the prion protein in lipid membranes leading to aggregation and fibrillization. Biochemistry 42:3295-3304.
18. Kim, C. L., et al. 2004. Cell-surface retention of PrPC by anti-PrP antibody prevents protease-resistant PrP formation. J. Gen. Virol. 85:3473-3482.
19. Kim, J. I., et al. 2010. Mammalian prions generated from bacterially expressed prion protein in the absence of any mammalian cofactors. J. Biol. Chem. 285:14083-14087.
20. Kim, J. I., K. Surewicz, P. Gambetti, and W. K. Surewicz. 2009. The role of glycophosphatidylinositol anchor in the amplification of the scrapie isoform of prion protein in vitro. FEBS Lett. 583:3671-3675.
21. Lehmann, S., and D. A. Harris. 1997. Blockade of glycosylation promotes acquisition of scrapie-like properties by the prion protein in cultured cells. J. Biol. Chem. 272:21479-21487.
22. Leucht, C., et al. 2003. The 37 kDa/67 kDa laminin receptor is required for PrP(Sc) propagation in scrapie-infected neuronal cells. EMBO Rep. 4:290-295. (Pubitemid 36511726)
23. McNally, K. L., A. E. Ward, and S. A. Priola. 2009. Cells expressing anchorless prion protein are resistant to scrapie infection. J. Virol. 83:4469-4475.
24. Murayama, Y., et al. 2007. Urinary excretion and blood level of prions in scrapie-infected hamsters. J. Gen. Virol. 88:2890-2898.
25. Murphy, V. F., W. C. Rowan, M. J. Page, and A. A. Holder. 1990. Expression of hybrid malaria antigens in insect cells and their engineering for correct folding and secretion. Parasitology 100:177-183.
26. Nagaoka, K., et al. 2010. Sensitive detection of scrapie prion protein in soil. Biochem. Biophys. Res. Commun. 397:626-630.
27. Paulick, M. G., and C. R. Bertozzi. 2008. The glycosylphosphatidylinositol anchor: a complex membrane-anchoring structure for proteins. Biochemistry 47:6991-7000.
28. Priola, S. A., and V. A. Lawson. 2001. Glycosylation influences cross-species formation of protease-resistant prion protein. EMBO J. 20:6692-6699.
29. Prusiner, S. B. 1998. Prions. Proc. Natl. Acad. Sci. U. S. A. 95:13363-13383.
30. Richardson, M. A., D. R. Smith, D. H. Kemp, and R. L. Tellam. 1993. Native and baculovirus-expressed forms of the immuno-protective protein BM86 from Boophilus microplus are anchored to the cell membrane by a glycosylphosphatidyl inositol linkage. Insect Mol. Biol. 1:139-147.
31. Saborio, G. P., B. Permanne, and C. Soto. 2001. Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding. Nature 411:810-813. (Pubitemid 32588105)
32. Shinagawa, M., et al. 1985. Characterization of scrapie agent isolated from sheep in Japan. Microbiol. Immunol. 29:543-551.
33. Thorne, L., and L. A. Terry. 2008. In vitro amplification of PrPSc derived from the brain and blood of sheep infected with scrapie. J. Gen. Virol. 89:3177-3184.
34. Wagner, R., et al. 1996. Elongation of the N-glycans of fowl plague virus hemagglutinin expressed in Spodoptera frugiperda (Sf9) cells by coexpression of human beta 1,2-N-acetylglucosaminyltransferase I. Glycobiology 6:165-175. (Pubitemid 26139060)
35. Wang, F., X. Wang, C. G. Yuan, and J. Ma. 2010. Generating a prion with bacterially expressed recombinant prion protein. Science 327:1132-1135.
36. Wong, C., et al. 2001. Sulfated glycans and elevated temperature stimulate PrP(Sc)-dependent cell-free formation of protease-resistant prion protein. EMBO J. 20:377-386. (Pubitemid 32126974)
37. Yokoyama, T., et al. 2001. In vivo conversion of cellular prion protein to pathogenic isoforms, as monitored by conformation-specific antibodies. J. Biol. Chem. 276:11265-11271.