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Volumn 1218, Issue 13, 2011, Pages 1677-1690
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A validated model for the simulation of protein purification through affinity membrane chromatography
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Author keywords
Affinity chromatography; Mathematical model; Membrane chromatography; Membrane column model; Protein purification
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Indexed keywords
ADSORPTION EQUILIBRIA;
AFFINITY MEMBRANES;
AXIAL DISPERSIONS;
BINDING KINETICS;
BINDING REACTION KINETICS;
CHROMATOGRAPHIC PURIFICATION;
COMPLEX MIXTURE;
EXPERIMENTAL DATA;
EXPERIMENTAL MEASUREMENTS;
MASS TRANSFER RESISTANCES;
MEMBRANE AFFINITY;
MEMBRANE CHROMATOGRAPHY;
MODEL CALCULATIONS;
MODEL PARAMETERS;
MODEL SIMULATION;
MODEL TESTING;
PARAMETER VALUES;
PHYSICAL MEANINGS;
POROUS MEMBRANES;
PROTEIN PURIFICATION;
THREE STAGES;
TRANSPORT PHENOMENA;
WASHING STEPS;
ADSORPTION;
AFFINITY CHROMATOGRAPHY;
COLUMN CHROMATOGRAPHY;
COMPUTER SIMULATION;
MEMBRANES;
PROTEINS;
PURIFICATION;
REACTION RATES;
WASHING;
MATHEMATICAL MODELS;
IMMUNOGLOBULIN G;
LYSOZYME;
ADSORPTION;
AFFINITY CHROMATOGRAPHY;
ALGORITHM;
ARTICLE;
COMPUTER SIMULATION;
CONTINUOUS STIRRED TANK REACTOR;
DYNAMICS;
FLOW RATE;
KINETICS;
MATHEMATICAL ANALYSIS;
MATHEMATICAL MODEL;
PLUG FLOW REACTOR;
POROSITY;
PRIORITY JOURNAL;
PROTEIN ANALYSIS;
PROTEIN PURIFICATION;
SEPARATION TECHNIQUE;
ADSORPTION;
CHROMATOGRAPHY, AFFINITY;
COMPUTER SIMULATION;
HUMANS;
IMMUNOGLOBULIN G;
KINETICS;
MEMBRANES, ARTIFICIAL;
MODELS, CHEMICAL;
PROTEIN BINDING;
PROTEINS;
REPRODUCIBILITY OF RESULTS;
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EID: 79952363589
PISSN: 00219673
EISSN: None
Source Type: Journal
DOI: 10.1016/j.chroma.2010.11.056 Document Type: Article |
Times cited : (47)
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References (72)
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