Computer-aided process design of affinity membrane adsorbers: A case study on antibodies capturing

Chemical Papers

Volumn 62, Issue 5, 2008, Pages 458-463

  Van Beijeren, Peter ^a   Kreis, Peter ^a   Hoffmann, Achim ^a   Mutter, Martina ^b   Sommerfeld, Sven ^b   Bäcker, Werner ^b   Górak, Andrzej ^a  

^a TU DORTMUND UNIVERSITY   (Germany)

^b BAYER AG   (Germany)

Author keywords

Affinity separation; Elution; Membrane chromatography; Monoclonal antibodies; Protein A

Indexed keywords

EID: 49649111918     PISSN: 03666352     EISSN: 13369075     Source Type: Journal    
DOI: 10.2478/s11696-008-0057-4     Document Type: Article

References (15)

1. B. H. Arve A. I. Liapis 1988 Modeling and analysis of elution stage of biospecific adsorption in finite bath Biotechnology and Bioengineering 31 240 249
2. S. Brandt R. A. Goffe S. B. Kessler J. L. O'Connor S. E. Zale 1988 Membrane-based affinity technology for commercial scale purifications Bio/Technology 6 779 782
3. L. Castilho F. Birger Anspach W. Deckwer 2002 Comparison of affinity membranes for the purification of immunoglobulins Journal of Membrane Science 207 253 264
4. W. Demmer D. Nussbaumer 1999 Large scale membrane adsorbers Journal of Chromatography A 852 73 81
5. S. Ghose B. Hubbard S. Cramer 2007 Binding capacity differences for antibodies and Fc-fusion proteins on protein A chromatographic materials Biotechnology and Bioengineering 96 768 779
6. R. Hahn R. Schlegel A. Jungbauer 2003 Comparison of protein A affinity sorbents Journal of Chromatography B 790 35 51
7. R. Hahn P. Bauerhansl K. Shimahara C. Wizniewski A. Tscheliessnig A. Jungbauer 2005 Comparison of protein A affinity sorbents: II. Mass transfer properties Journal of Chromatography A 1093 98 110
8. H. Liu J. Fried 1994 Breakthrough of lysozyme through an affinity membrane of cellulose-Cibacron blue AIChE Journal 40 40 49
9. R. Montesinos-Cisneros J. Ortega R. Guzman A. Tejeda-Mansir 2006 Breakthrough performance of linear-DNA on ion-exchange membrane columns Bioprocess and Biosystems Engineering 29 91 98
10. S. Suen M. R. Etzel 1992 A mathematical analysis of affinity membrane bioseparations Chemical Engineering Science 47 1355 1364
11. S. Suen M. R. Etzel 1994 Sorption kinetics and break-through curves for pepsin and chymosin using pepstatin A affinity membranes Journal of Chromatography A 686 179 192
12. A. Tejeda J. Ortega I. Magana R. Guzman 1999 Optimal design of affinity membrane chromatographic columns Journal of Chromatography A 80 293 300
13. H. C. Thomas 1944 Heterogeneous ion exchange in a flowing system Journal of the American Chemical Society 66 1664 1666
14. H. C. Thomas 1948 Chromatography: a problem in kinetics Annals of the New York Academy of Sciences 49 161 182
15. van Beijeren, P., Kreis, P., Mutter, M., Sommerfeld, S., Bäcker, W., & Górak, A. (2007). Computer aided process design of affinity membrane adsorbers. Presented at the 1st European Process Intensification Conference, September 19-20, Copenhagen, Denmark.