메뉴 건너뛰기




Volumn 70, Issue 4, 2011, Pages 695-699

The cannabinoid WIN55,212-2 abrogates dermal fibrosis in scleroderma bleomycin model

Author keywords

[No Author keywords available]

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; ALPHA SMOOTH MUSCLE ACTIN; BLEOMYCIN; CONNECTIVE TISSUE GROWTH FACTOR; HYDROXYPROLINE; PLATELET DERIVED GROWTH FACTOR BB; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 79952363189     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/ard.2010.137539     Document Type: Article
Times cited : (50)

References (19)
  • 1
    • 33847348491 scopus 로고    scopus 로고
    • Systemic sclerosis: A prototypic multisystem fibrotic disorder
    • DOI 10.1172/JCI31139
    • Varga J, Abraham D. Systemic sclerosis :a prototypic multisystem fibrotic disorder. J Clin Invest 2007;117:557-67. (Pubitemid 46348510)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.3 , pp. 557-567
    • Varga, J.1    Abraham, D.2
  • 2
    • 33847392947 scopus 로고    scopus 로고
    • New developments in fibroblast and myofibroblast biology: Implications for fibrosis and scleroderma
    • DOI 10.1007/s11926-007-0008-z
    • Abraham DJ, Eckes B, Rajkumar V, et al. New developments in fibroblast and myofibroblast biology: implications for fibrosis and scleroderma. Curr Rheumatol Rep 2007;9:136-43. (Pubitemid 46932720)
    • (2007) Current Rheumatology Reports , vol.9 , Issue.2 , pp. 136-143
    • Abraham, D.J.1    Eckes, B.2    Rajkumar, V.3    Krieg, T.4
  • 3
    • 0036448477 scopus 로고    scopus 로고
    • The role of TGF-beta signaling in the pathogenesis of fibrosis in scleroderma
    • Ihn H. The role of TGF-beta signaling in the pathogenesis of fibrosis in scleroderma. Arch Immunol Ther Exp (Warsz) 2002;50:325-31. (Pubitemid 35434568)
    • (2002) Archivum Immunologiae et Therapiae Experimentalis , vol.50 , Issue.5 , pp. 325-331
    • Ihn, H.1
  • 4
    • 2142646426 scopus 로고    scopus 로고
    • TGF-beta signaling and the fibrotic response
    • Leask A, Abraham DJ. TGF-beta signaling and the fibrotic response. FASEB J 2004;18:816-27.
    • (2004) FASEB J , vol.18 , pp. 816-827
    • Leask, A.1    Abraham, D.J.2
  • 5
    • 75649096395 scopus 로고    scopus 로고
    • Mechanisms of skin fibrosis in systemic sclerosis
    • Jinnin M. Mechanisms of skin fibrosis in systemic sclerosis. J Dermatol 2010;37:11-25.
    • (2010) J Dermatol , vol.37 , pp. 11-25
    • Jinnin, M.1
  • 6
    • 0031911356 scopus 로고    scopus 로고
    • SMADs: Mediators and regulators of TGF-beta signaling
    • Kretzschmar M, Massagué J. SMADs: mediators and regulators of TGF-beta signaling. Curr Opin Genet Dev 1998;8:103-11
    • (1998) Curr Opin Genet Dev , vol.8 , pp. 103-111
    • Kretzschmar, M.1    Massagué, J.2
  • 7
    • 0038004796 scopus 로고    scopus 로고
    • Expression and regulation of intracellular SMAD signaling in scleroderma skin fibroblasts
    • Mori Y, Chen SJ, Varga J. Expression and regulation of intracellular SMAD signaling in scleroderma skin fibroblasts. Arthritis Rheum 2003;48:1964-78.
    • (2003) Arthritis Rheum , vol.48 , pp. 1964-1978
    • Mori, Y.1    Chen, S.J.2    Varga, J.3
  • 8
    • 39149111573 scopus 로고    scopus 로고
    • The endocannabinoid system as a novel target for the treatment of liver fibrosis
    • Teixeira-Clerc F, Julien B, Grenard P, et al. T he endocannabinoid system as a novel target for the treatment of liver fibrosis. Pathol Biol 2008;56:36-8.
    • (2008) Pathol Biol , vol.56 , pp. 36-38
    • Teixeira-Clerc, F.1    Julien, B.2    Grenard, P.3
  • 9
    • 28944453205 scopus 로고    scopus 로고
    • Cannabinoid signalling
    • Demuth D G, Molleman A. Cannabinoid signalling. Life Sci 2006;78:549-63.
    • (2006) Life Sci , vol.78 , pp. 549-563
    • Demuth, D.G.1    Molleman, A.2
  • 10
    • 63449105700 scopus 로고    scopus 로고
    • Role of cannabinoids in chronic liver diseases
    • Parfieniuk A, Flisiak R. Role of cannabinoids in chronic liver diseases. World J Gastroenterol 2008;14:6109-14.
    • (2008) World J Gastroenterol , vol.14 , pp. 6109-6114
    • Parfieniuk, A.1    Flisiak, R.2
  • 11
    • 47049123545 scopus 로고    scopus 로고
    • Cannabinoids reduce markers of inflammation and fibrosis in pancreatic stellate cells
    • Michalski CW, Maier M, Erkan M, et al. Cannabinoids reduce markers of inflammation and fibrosis in pancreatic stellate cells. PLoS ONE 2008;3:e1701.
    • (2008) PLoS ONE , vol.3
    • Michalski, C.W.1    Maier, M.2    Erkan, M.3
  • 12
    • 65249092549 scopus 로고    scopus 로고
    • The cannabinoid receptor CB2 exerts antifibrotic effects in experimental dermal fibrosis
    • Akhmetshina A, Dees C, Busch N, et al. The cannabinoid receptor CB2 exerts antifibrotic effects in experimental dermal fibrosis. Arthritis Rheum 2009;60:1129-36.
    • (2009) Arthritis Rheum , vol.60 , pp. 1129-1136
    • Akhmetshina, A.1    Dees, C.2    Busch, N.3
  • 13
    • 77954574870 scopus 로고    scopus 로고
    • Targeting the cannabinoid pathway limits the development of fibrosis and autoimmunity in a mouse model of systemic sclerosis
    • Servettaz A, Kavian N, Nicco C, et al. Targeting the cannabinoid pathway limits the development of fibrosis and autoimmunity in a mouse model of systemic sclerosis. Am J Pathol 2010;177:187-96.
    • (2010) Am J Pathol , vol.177 , pp. 187-196
    • Servettaz, A.1    Kavian, N.2    Nicco, C.3
  • 14
    • 70349785531 scopus 로고    scopus 로고
    • Cannabinoids inhibit fibrogenesis in diffuse systemic sclerosis fibroblasts
    • Garcia-Gonzalez E, Selvi E, Balistreri E, et al. Cannabinoids inhibit fibrogenesis in diffuse systemic sclerosis fibroblasts. Rheumatology (Oxford) 2009;48:1050-6.
    • (2009) Rheumatology (Oxford) , vol.48 , pp. 1050-1056
    • Garcia-Gonzalez, E.1    Selvi, E.2    Balistreri, E.3
  • 15
    • 0014154262 scopus 로고
    • Comparison of poly-L-proline I and II as inhibitors of protocollagen hydroxylase
    • Kivirikko K I, Ganser V, Engel J, et al. Comparison of poly-L-proline I and II as inhibitors of protocollagen hydroxylase. Hoppe-Seyler's Z Physiol Chem 1967;348:1341-4.
    • (1967) Hoppe-Seyler's Z Physiol Chem , vol.348 , pp. 1341-1344
    • Kivirikko, K.I.1    Ganser, V.2    Engel, J.3
  • 16
    • 65849108890 scopus 로고    scopus 로고
    • Role of PDGF in fibrotic diseases and systemic sclerosis
    • Trojanowska M. Role of PDGF in fibrotic diseases and systemic sclerosis. Rheumatology (Oxford) 2008;47 (Suppl 5):v2-4.
    • (2008) Rheumatology (Oxford) , vol.47 , Issue.SUPPL. 5
    • Trojanowska, M.1
  • 17
    • 31344473454 scopus 로고    scopus 로고
    • The bleomycin-induced scleroderma model:What have we learned for scleroderma pathogenesis?
    • Yamamoto T. The bleomycin-induced scleroderma model:what have we learned for scleroderma pathogenesis? Arch Dermatol Res 2006;297:333-44.
    • (2006) Arch Dermatol Res , vol.297 , pp. 333-344
    • Yamamoto, T.1
  • 18
    • 75649110070 scopus 로고    scopus 로고
    • Animal model of systemic sclerosis
    • Yamamoto T. Animal model of systemic sclerosis. J Dermatol 2010;37:26-41.
    • (2010) J Dermatol , vol.37 , pp. 26-41
    • Yamamoto, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.