Protein tyrosine phosphatase SHP-2 is positively involved in platelet-derived growth factor-signaling in vascular neointima formation via the reactive oxygen species-related pathway

Journal of Pharmacological Sciences

Volumn 115, Issue 2, 2011, Pages 164-175

  Won, Kyung Jong ^a   Lee, Hwan Myung ^b   Lee, Chang Kwon ^a   Lin, Hai Yue ^a   Na, Haerang ^a   Lim, Ki Won ^a   Roh, Hui Yul ^a   Sim, Seobo ^a   Song, Hyuk ^a   Choi, Wahn Soo ^a   Lee, Seung Hyun ^a   Kim, Bokyung ^a  

^a Konkuk University School of Medicine   (South Korea)

^b Hoseo University   (South Korea)

Author keywords

Migration; Platelet derived growth factor (PDGF) BB; Reactive oxygen species (ROS); SHP 2; Vascular remodeling

Indexed keywords

8 HYDROXY 7 (6 SULFONAPHTHALEN 2 YL)DIAZENYL QUINOLINE 5 SULFONIC ACID; BETA ACTIN; ENZYME INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR BB; PROTEIN KINASE SYK; PROTEIN TYROSINE PHOSPHATASE SHP 2; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA MEDIA; ARTICLE; CAROTID ARTERY; CELL MIGRATION; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; IMMUNOBLOTTING; MALE; NEOINTIMA; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SIGNAL TRANSDUCTION;

EID: 79952326349     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.10250FP     Document Type: Article

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