Urinary N-methylhistamine in asthmatic children receiving azelastine hydrochloride

Annals of Allergy, Asthma and Immunology

Volumn 78, Issue 5, 1997, Pages 492-496

  Takei, Syuji ^a,d   Shimago, Atsushi ^a   Iwashita, Mayumi ^a   Kumamoto, Toshinori ^b   Kamuro, Kazuhiro ^c   Miyata, Koichiro ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b Department of Obstetrics and Gynecology   (Japan)

^c Department of Pediatrics   (Japan)

^d NONE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOPHYLLINE; AZELASTINE; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; BRONCHODILATING AGENT; EXPECTORANT AGENT; N METHYLHISTAMINE;

ARTICLE; ASTHMA; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DAILY LIFE ACTIVITY; FEMALE; HUMAN; INHALATIONAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RADIOIMMUNOASSAY; SLEEP; URINARY EXCRETION;

EID: 0030923842     PISSN: 10811206     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1081-1206(10)63237-1     Document Type: Article

References (16)

1. Bainton DF. The cells of inflammation: a general view. In: Weissmann G, eds. The cell biology of inflammation. Amsterdam: New York and Oxford Elesevier/North-Holland Biochemical Press, 1980:18-25.
2. Holgate S, Robinson C, Church M, Howarth P. The release and role of inflammatory mediators in asthma. Clin Immunol Rev 1985;4:241-88.
3. Zechel HJ, Brock N, Lenke D, Achterrath-Tuckermann U. Pharmacological and toxicological properties of azelastine, a novel antiallergic agent. Arzneimittel-Forsch 1981;31: 1184-93.
4. Katayama S, Akimoto N, Shionoya H, et al. Anti-allergic effect of azelastine hydrochloride on immediate type hypersensitivity reactions in vivo and in vitro. Arzneim-Forsch/Drug Res 1981; 31:1196-203.
5. Chand N, Harrison JE, Rooney SM, Sofia RD. Inhibition of passive cutaneous anaphylaxis (PCA) by azelastine: dissociation of its antiallergic activities from antihistaminic and antiserotonin properties. Int J Immunopharmacol 1985;7:833-8.
6. Chand N, Pillar J, Diamantis W, et al. Inhibition of calcium ionophore (A23187)-stimulated histamine release from rat peritoneal mast cells by azelastine: implications for its mode of action. Eur J Pharmacol 1983;96: 227-33.
7. Fields DAS, Pillar J, Diamantis W, et al. Inhibition by azelastine of nonallergic histamine release from rat peritoneal mast cells. J Allergy Clin Immunol 1984;73:400-3.
8. Chand N, Pillar J, Diamantis W, Sofia RD. Inhibition of allergic histamine release by azelastine and selected antiallergic drugs from rabbit leukocytes. Int Arch Allergy Appl Immunol 1985;77: 451-5.
9. Chand N, Pillar J, Nolan K. et al. Inhibition of allergic and nonallergic leukotriene C4 formation and histamine secretion by azelastine: implication for its mechanism of action. Int Arch Allergy Immunol 1989;90:67-70.
10. McBride P, Bradley D, Kaliner M. Evaluation of a radioimmunoassay for histamine measurement in biological fluids. J Allergy Clin Immunol 1988; 82:638-46.
11. Wood-Baker R, Finnerty JP, Holgate ST. Plasma and urinary histamine in allergen-induced early and late phase asthmatic responses. Eur Respir J 1993;6:1138-44.
12. van Aalderen WMC, Postma DS, Koeter GH, Knol K. Nocturnal airflow obstruction, histamine, and the autonomic central nervous system in children with allergic asthma. Thorax 1994;46:366-71.
13. Mikawa H, Baba M. Diagnosis and treatment of bronchial asthma in children. In: Makino S. ed. The guideline for treatment of allergic disorders, Tokyo, Life Science Medica, 1993: 40-60.
14. Zimmermann A, Urbanek R, Kuhr J, Stephan V. Urinary N-methylhistamine excretion following exogenous histamine administration and allergy/exercise-induced bronchoconstriction. Monatsschr-Kinderheilkd 1992;140: 51-6.
15. Akagi M, Mio M, Tasaka K, Kiniwa S. Mechanism of histamine release inhibition induced by azelastine. Pharmacometrics 1983;26:191-8.
16. Matsumura M, Matsumoto Y, Takahashi H, et al. Inhibitory effects of azelastine on leukotrienes B4, C4 and D4 release and production from asthmatic eosinophils. Kokyu 1990;9: 206-12.